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Navraj S. Pannu
Researcher at Leiden University
Publications - 68
Citations - 37578
Navraj S. Pannu is an academic researcher from Leiden University. The author has contributed to research in topics: Likelihood function & Crystal structure. The author has an hindex of 25, co-authored 65 publications receiving 34400 citations. Previous affiliations of Navraj S. Pannu include University of Alberta & University of Cambridge.
Papers
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Journal ArticleDOI
Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination
Axel T. Brunger,Axel T. Brunger,Paul D. Adams,G M Clore,W. L. DeLano,Piet Gros,R.W. Grosse-Kunstleve,R.W. Grosse-Kunstleve,Jiansheng Jiang,J. Kuszewski,Michael Nilges,Navraj S. Pannu,Randy J. Read,Luke M. Rice,Thomas Simonson,Gregory L. Warren +15 more
TL;DR: The Crystallography & NMR System (CNS) as mentioned in this paper is a software suite for macromolecular structure determination by X-ray crystallography or solution nuclear magnetic resonance (NMR) spectroscopy.
Journal ArticleDOI
Overview of the CCP4 suite and current developments.
Martyn Winn,Charles Ballard,Kevin Cowtan,Eleanor J. Dodson,Paul Emsley,Phil Evans,Ronan M. Keegan,Eugene Krissinel,Andrew G. W. Leslie,Airlie J. McCoy,Stuart McNicholas,Garib N. Murshudov,Navraj S. Pannu,E. Potterton,Harold R. Powell,Randy J. Read,Alexei A. Vagin,Keith S. Wilson +17 more
TL;DR: An overview of the CCP4 software suite for macromolecular crystallography is given.
Journal ArticleDOI
REFMAC5 for the refinement of macromolecular crystal structures
Garib N. Murshudov,Pavol Skubák,Andrey Lebedev,Navraj S. Pannu,Roberto A. Steiner,Robert A. Nicholls,Winn,Fei Long,Alexei A. Vagin +8 more
TL;DR: The general principles behind the macromolecular crystal structure refinement program REFMAC5 are described.
Journal ArticleDOI
Shiga-like toxins are neutralized by tailored multivalent carbohydrate ligands
Pavel I. Kitov,Joanna M. Sadowska,George L. Mulvey,Glen D. Armstrong,Hong Ling,Navraj S. Pannu,Randy J. Read,Randy J. Read,David R. Bundle +8 more
TL;DR: The crystal structure of the B5 subunit of Escherichia coli O157:H7 Shiga-like toxin I in complex with an analogue of its carbohydrate receptor is used to design an oligovalent, water-soluble carbohydrate ligand (named STARFISH), with subnanomolar inhibitory activity.
Journal ArticleDOI
Improved Structure Refinement Through Maximum Likelihood
Navraj S. Pannu,Randy J. Read +1 more
TL;DR: In this article, the authors proposed a method based on maximum likelihood and two maximum-likelihood targets have been implemented in the program XPLOR to improve the accuracy and precision of the atomic coordinates.