P
Phil Evans
Researcher at Laboratory of Molecular Biology
Publications - 9
Citations - 11839
Phil Evans is an academic researcher from Laboratory of Molecular Biology. The author has contributed to research in topics: Small nuclear RNA & Binding domain. The author has an hindex of 6, co-authored 9 publications receiving 10173 citations.
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Journal ArticleDOI
Overview of the CCP4 suite and current developments.
Martyn Winn,Charles Ballard,Kevin Cowtan,Eleanor J. Dodson,Paul Emsley,Phil Evans,Ronan M. Keegan,Eugene Krissinel,Andrew G. W. Leslie,Airlie J. McCoy,Stuart McNicholas,Garib N. Murshudov,Navraj S. Pannu,E. Potterton,Harold R. Powell,Randy J. Read,Alexei A. Vagin,Keith S. Wilson +17 more
TL;DR: An overview of the CCP4 software suite for macromolecular crystallography is given.
Journal ArticleDOI
CCP4i2: the new graphical user interface to the CCP4 program suite.
Liz Potterton,Jon Agirre,Charles Ballard,Kevin Cowtan,Eleanor J. Dodson,Phil Evans,Huw T. Jenkins,Ronan M. Keegan,Eugene Krissinel,Kyle Stevenson,Andrey Lebedev,Stuart McNicholas,Robert A. Nicholls,Martin E.M. Noble,Navraj S. Pannu,Christian Roth,George M. Sheldrick,Pavol Skubák,Johan P. Turkenburg,Ville Uski,Frank von Delft,David G. Waterman,Keith S. Wilson,Martyn Winn,Marcin Wojdyr +24 more
TL;DR: CCP4i2 is a graphical user interface to the CCP4 (Collaborative Computational Project, Number 4) software suite and a Python language framework for software automation.
Journal ArticleDOI
The RNP domain: a sequence-specific RNA-binding domain involved in processing and transport of RNA.
TL;DR: The crystal structure of a complex between the U1A spliceosomal protein and its cognate RNA hairpin at 1.92 A resolution reveals the molecular basis of sequence-specific RNA recognition by the RNP domain.
Journal ArticleDOI
Decoding of Methylated Histone H3 Tail by the Pygo- Bcl9 Wnt Signaling Complex.
Marc Fiedler,María José Sánchez-Barrena,Maxim Nekrasov,Juliusz Mieszczanek,Vladimir Rybin,Jürg Müller,Phil Evans,Mariann Bienz +7 more
TL;DR: It is shown that human and Drosophila Pygo PHD fingers associate with their cognate HD1 domains from BCL9/Legless to bind specifically to the histone H3 tail methylated at lysine 4 (H3K4me).
Journal ArticleDOI
Resolving Some Old Problems in Protein Crystallography
TL;DR: Two methods improve the quality and ease of structural modeling by showing how to include diffraction data that are often thrown away, and averaging data from multiple crystals can give helpful information for solving the phase problem by using intrinsic sulfur atoms in the protein, circumventing the need to introduce heavier atoms.