Neil G. Paterson

TL;DR: Bulk alterations in the normal posterior sCleral collagen microstructure occur in human eyes with high myopia, which could reflect remodeling of the posterior sclera during axial lengthening and/or a mechanical adaption to tissue stresses induced by fluid pressure or eye movements that may be exacerbated in enlarged eyes.

TL;DR: An antibody, EY6A, is isolated from a late-stage COVID-19 patient and it neutralises Sars-CoV-2 and cross-reacts with SARS- CoV-1 and is shown to bind what is probably a major neutralising epitope, making it a candidate therapeutic for CO VID-19.

TL;DR: It is proposed that wsluc1–3 form a complex that crystallises inside the squid photophores, and that in the crystal one or more of the proteins catalyses the production of light using coelenterazine disulfate and ATP.

TL;DR: A short overview of the emerging use of collecting X-ray diffraction data directly from the crystallization experiment and a practical guide to the use of the method on the MX suite of beamlines at Diamond Light Source is given.

TL;DR: Functional validation using a novel NMR approach has demonstrated that the PruA and PruB enzymes are together sufficient to convert proline to glutamate, the first such demonstration for monofunctional proline-utilization enzymes.