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Nicola J Wiles
Researcher at University of Bristol
Publications - 152
Citations - 7760
Nicola J Wiles is an academic researcher from University of Bristol. The author has contributed to research in topics: Randomized controlled trial & Beck Depression Inventory. The author has an hindex of 48, co-authored 142 publications receiving 6699 citations. Previous affiliations of Nicola J Wiles include University of Manchester & University Hospitals Bristol NHS Foundation Trust.
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Mortality in early inflammatory polyarthritis: Cardiovascular mortality is increased in seropositive patients
TL;DR: Excess mortality in the early years of IP is confined to patients who are seropositive for RF, and while excess cardiovascular mortality has been described in patients with established RA, this is the first report of premature death from heart disease in theEarly Years of IP.
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Therapist-delivered internet psychotherapy for depression in primary care: a randomised controlled trial
David Kessler,Glyn Lewis,Surinder Kaur,Nicola J Wiles,Michael King,Scott Weich,Deborah Sharp,Ricardo Araya,Sandra Hollinghurst,Tim J Peters +9 more
TL;DR: CBT seems to be effective when delivered online in real time by a therapist, with benefits maintained over 8 months, with this method of delivery could broaden access to CBT.
Journal ArticleDOI
Cognitive behavioural therapy as an adjunct to pharmacotherapy for primary care based patients with treatment resistant depression: Results of the CoBalT randomised controlled trial
Nicola J Wiles,Laura Thomas,Anna Abel,Nicola Ridgway,Nicholas L Turner,John Campbell,Anne Garland,Sandra Hollinghurst,Bill Jerrom,David Kessler,Willem Kuyken,Jill Morrison,Katrina M Turner,Christopher Williams,Tim J Peters,Glyn Lewis +15 more
TL;DR: This study has provided robust evidence that CBT as an adjunct to usual care that includes antidepressants is an effective treatment, reducing depressive symptoms in this population of patients with treatment resistant depression.
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The impact of rheumatoid arthritis on employment status in the early years of disease: a UK community‐based study
TL;DR: Although the peak rates for work disability are in the early years, people with RA continue to leave the work force several years after onset, and the recent move to earlier, more aggressive treatment has had no effect on the rates of work disability.
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Self-reported psychotic symptoms in the general population: results from the longitudinal study of the British National Psychiatric Morbidity Survey
TL;DR: A small but not insignificant percentage of the population of Great Britain reported incident psychotic symptoms over 18 months, and the risk factors for psychotic symptoms showed some similarities withrisk factors for schizophrenia, but there were also some striking differences.