N
Nicolas Leulliot
Researcher at Paris Descartes University
Publications - 85
Citations - 3027
Nicolas Leulliot is an academic researcher from Paris Descartes University. The author has contributed to research in topics: Structural genomics & Protein structure. The author has an hindex of 32, co-authored 81 publications receiving 2747 citations. Previous affiliations of Nicolas Leulliot include University of Paris & Pierre-and-Marie-Curie University.
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Current topics in RNA-protein recognition: control of specificity and biological function through induced fit and conformational capture.
Nicolas Leulliot,Gabriele Varani +1 more
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Shared genetic predisposition in rheumatoid arthritis-interstitial lung disease and familial pulmonary fibrosis.
Pierre-Antoine Juge,Raphael Borie,Caroline Kannengiesser,Steven Gazal,Steven Gazal,Patrick Revy,Patrick Revy,Lidwine Wemeau-Stervinou,Marie-Pierre Debray,Sébastien Ottaviani,Sylvain Marchand-Adam,Sylvain Marchand-Adam,Nadia Nathan,Nadia Nathan,Gabriel Thabut,Gabriel Thabut,Christophe Richez,Christophe Richez,Hilario Nunes,Isabelle Callebaut,Isabelle Callebaut,Aurélien Justet,Nicolas Leulliot,Nicolas Leulliot,Amélie Bonnefond,Amélie Bonnefond,David Salgado,David Salgado,Pascal Richette,Pascal Richette,Jean-Pierre Desvignes,Jean-Pierre Desvignes,Huguette Lioté,Philippe Froguel,Philippe Froguel,Philippe Froguel,Yannick Allanore,Yannick Allanore,Olivier Sand,Olivier Sand,Claire Dromer,René-Marc Flipo,Annick Clement,Annick Clement,Christophe Béroud,Christophe Béroud,Jean Sibilia,Baptiste Coustet,Vincent Cottin,Marie-Christophe Boissier,Marie-Christophe Boissier,Benoit Wallaert,Thierry Schaeverbeke,Thierry Schaeverbeke,Florence Dastot-Le Moal,Aline Frazier,Christelle Ménard,Christelle Ménard,Martin Soubrier,Nathalie Saidenberg,Dominique Valeyre,Serge Amselem,Catherine Boileau,Catherine Boileau,Bruno Crestani,Bruno Crestani,Philippe Dieudé,Philippe Dieudé +67 more
TL;DR: The results support the contribution of FPF-linked genes to RA-ILD susceptibility, including TERT, RTEL1, PARN and SFTPC mutations to rheumatoid interstitial lung disease susceptibility.
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Prp43p contains a processive helicase structural architecture with a specific regulatory domain.
Hélène Walbott,Saïda Mouffok,Saïda Mouffok,Régine Capeyrou,Régine Capeyrou,Simon Lebaron,Simon Lebaron,Odile Humbert,Odile Humbert,Herman van Tilbeurgh,Yves Henry,Yves Henry,Nicolas Leulliot,Nicolas Leulliot +13 more
TL;DR: The structure of yeast Prp43p is reported, a DEAH/RHA helicase remarkable in that it functions in both splicing and ribosome biogenesis and the C‐terminal domain is proposed to be a central player in the regulation of helicase activity by binding both RNA and G‐patch domain proteins.
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Ground-State Properties of Nucleic Acid Constituents Studied by Density Functional Calculations. 3. Role of Sugar Puckering and Base Orientation on the Energetics and Geometry of 2‘-Deoxyribonucleosides and Ribonucleosides
TL;DR: In this article, the conformational energy and geometrical parameters of isolated 2'deoxyribonucleosides and ribon nucleosides were analyzed by means of density functional theory with the Becke−Lee−Yang−Parr exchange.
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Insertion of the Biogenesis Factor Rei1 Probes the Ribosomal Tunnel during 60S Maturation
Basil J. Greber,Stefan Gerhardy,Alexander Leitner,Marc Leibundgut,Michèle Salem,Daniel Boehringer,Nicolas Leulliot,Ruedi Aebersold,Ruedi Aebersold,Vikram Govind Panse,Nenad Ban +10 more
TL;DR: Cryo-electron microscopy (cryo-EM) structure of the yeast 60S subunit in complex with the biogenesis factors Rei1, Arx1, and Alb1 reveals a mechanism for ensuring the integrity of the ribosomal polypeptide exit tunnel.