A
Amélie Bonnefond
Researcher at Pasteur Institute
Publications - 192
Citations - 14828
Amélie Bonnefond is an academic researcher from Pasteur Institute. The author has contributed to research in topics: Type 2 diabetes & Medicine. The author has an hindex of 45, co-authored 148 publications receiving 12994 citations. Previous affiliations of Amélie Bonnefond include Pasteur Institute of Lille & University of Paris.
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Journal ArticleDOI
New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk
Josée Dupuis,Josée Dupuis,Claudia Langenberg,Inga Prokopenko,Richa Saxena,Richa Saxena,Nicole Soranzo,Nicole Soranzo,Anne U. Jackson,Eleanor Wheeler,Nicole L. Glazer,Nabila Bouatia-Naji,Anna L. Gloyn,Cecilia M. Lindgren,Reedik Mägi,Andrew P. Morris,Joshua C. Randall,Toby Johnson,Toby Johnson,Paul Elliott,Paul Elliott,Denis Rybin,Gudmar Thorleifsson,Valgerdur Steinthorsdottir,Peter Henneman,Harald Grallert,Abbas Dehghan,Jouke JanHottenga,Christopher S. Franklin,Pau Navarro,Kijoung Song,Anuj Goel,John R. B. Perry,Josephine M. Egan,Taina K. Lajunen,Niels Grarup,Thomas Sparsø,Alex S. F. Doney,Benjamin F. Voight,Benjamin F. Voight,Heather M. Stringham,Man Li,Stavroula Kanoni,Peter Shrader,Christine Cavalcanti-Proença,Meena Kumari,Lu Qi,Nicholas J. Timpson,Christian Gieger,Carina Zabena,Ghislain Rocheleau,Erik Ingelsson,Erik Ingelsson,Ping An,Jeffrey R. O'Connell,Jian'an Luan,Amanda F. Elliott,Amanda F. Elliott,Steven A. McCarroll,Steven A. McCarroll,Felicity Payne,Rosa Maria Roccasecca,François Pattou,Praveen Sethupathy,Kristin Ardlie,Yavuz Ariyurek,Beverley Balkau,Philip J. Barter,John Beilby,Yoav Ben-Shlomo,Rafn Benediktsson,Amanda J. Bennett,Sven Bergmann,Sven Bergmann,Murielle Bochud,Eric Boerwinkle,Amélie Bonnefond,Lori L. Bonnycastle,Knut Borch-Johnsen,Knut Borch-Johnsen,Yvonne Böttcher,Eric J. Brunner,Suzannah Bumpstead,Guillaume Charpentier,Yii Der IdaChen,Peter S. Chines,Robert Clarke,Lachlan J. McOin,Mark E. Cooper,Marilyn C. Cornelis,Gabe Crawford,Laura Crisponi,Ian N. M. Day,Eco J. C. de Geus,Jérôme Delplanque,Christian Dina,Michael R. Erdos,A C Fedson,Antje Fischer-Rosinsky,Nita G. Forouhi,Caroline S. Fox,Caroline S. Fox,Rune R. Frants,Maria GraziaFranzosi,Pilar Galan,Mark O. Goodarzi,J. Graessler,Christopher J. Groves,Scott M. Grundy,Rhian Gwilliam,Ulf Gyllensten,Samy Hadjadj,Göran Hallmans,Naomi Hammond,Xijing Han,Anna LiisaHartikainen,Neelam Hassanali,Caroline Hayward,Simon Heath,Serge Hercberg,Christian Herder,Andrew A. Hicks,David R. Hillman,Aroon D. Hingorani,Albert Hofman,Jennie Hui,Joseph Hung,Joseph Hung,Bo Isomaa,Paul Johnson,Torben Jørgensen,Antti Jula,Marika Kaakinen,Jaakko Kaprio,Jaakko Kaprio,Y. AnteroKesaniemi,Mika Kivimäki,Beatrice Knight,Seppo Koskinen,Peter Kovacs,Kirsten Ohm Kyvik,G. Mark Lathrop,Debbie A Lawlor,Olivier Le Bacquer,Cécile Lecoeur,Yun Li,Valeriya Lyssenko,Robert W. Mahley,Massimo Mangino,Alisa K. Manning,María TeresaMartínez-Larrad,Jarred B. McAteer,Jarred B. McAteer,Laura J. McCulloch,Ruth McPherson,Christa Meisinger,David Melzer,David Meyre,Braxton D. Mitchell,Mario A. Morken,Sutapa Mukherjee,Silvia Naitza,Narisu Narisu,Matt Neville,Ben A. Oostra,Marco Orrù,Ruth E. Pakyz,Colin N. Apalmer,Giuseppe Paolisso,Cristian Pattaro,Daniel S. Pearson,John F. Peden,Nancy L. Pedersen,Markus Perola,Markus Perola,Andreas Pfeiffer,Irene Pichler,Ozren Polasek,Danielle Posthuma,Simon C. Potter,Anneli Pouta,Michael A. Province,Bruce M. Psaty,Bruce M. Psaty,Wolfgang Rathmann,Nigel W. Rayner,Kenneth Rice,Samuli Ripatti,Samuli Ripatti,Fernando Rivadeneira,Michael Roden,Olov Rolandsson,Annelli Sandbæk,Manjinder S. Sandhu,Serena Sanna,Avan Aihie Sayer,Paul Scheet,Laura J. Scott,Udo Seedorf,Stephen J. Sharp,Beverley M. Shields,Gunnar Sigursson,Eric J.G. Sijbrands,Angela Silveira,Laila Simpson,Andrew B. Singleton,Nicholas L. Smith,Nicholas L. Smith,Ulla Sovio,Amy J. Swift,Holly E. Syddall,Ann ChristineSyvänen,Toshiko Tanaka,Toshiko Tanaka,Barbara Thorand,Jean Tichet,Anke Tönjes,Tiinamaija Tuomi,André G. Uitterlinden,Ko Willems van Dijk,Mandy van Hoek,Dhiraj Varma,Sophie Visvikis-Siest,Veronique Vitart,Nicole Vogelzangs,Gerard Waeber,Peter Wagner,Peter Wagner,Andrew Walley,G. BragiWalters,Kim L. Ward,Hugh Watkins,Michael N. Weedon,Sarah H. Wild,Gonneke Willemsen,Jaqueline C. MWitteman,John W. GYarnell,Eleftheria Zeggini,Eleftheria Zeggini,Diana Zelenika,Björn Zethelius,Björn Zethelius,Guangju Zhai,Jing Hua Zhao,M. Carola Zillikens,Ingrid B. Borecki,Ruth J. F. Loos,Pierre Meneton,Patrik K. E. Magnusson,David M. Nathan,Gordon H. Williams,Andrew T. Hattersley,Kaisa Silander,Kaisa Silander,Veikko Salomaa,George Davey Smith,Stefan R. Bornstein,Peter Schwarz,Joachim Spranger,Fredrik Karpe,Alan R. Shuldiner,Cyrus Cooper,George Dedoussis,Manuel Serrano-Ríos,Andrew D. Morris,Lars Lind,Lyle J. Palmer,Lyle J. Palmer,Frank B. Hu,Paul W. Franks,Shah Ebrahim,Michael Marmot,W. H. Linda Kao,James S. Pankow,Mike Sampson,Johanna Kuusisto,Markku Laakso,Torben Hansen,Torben Hansen,Oluf Pedersen,Oluf Pedersen,Oluf Pedersen,Peter P. Pramstaller,H.-Erich Wichmann,Thomas Illig,Igor Rudan,Igor Rudan,Alan F. Wright,Michael Stumvoll,Harry Campbell,James F. Wilson,Richard N. Bergman,Thomas A. Buchanan,Francis S. Collins,Karen L. Mohlke,Jaakko Tuomilehto,Jaakko Tuomilehto,Timo T. Valle,David Altshuler,David Altshuler,Jerome I. Rotter,David S. Siscovick,Brenda W.J.H. Penninx,Dorret I. Boomsma,Panos Deloukas,Tim D. Spector,Tim D. Spector,Timothy M. Frayling,Luigi Ferrucci,Augustine Kong,Unnur Thorsteinsdottir,Unnur Thorsteinsdottir,Kari Stefansson,Kari Stefansson,Cornelia M. van Duijn,Yurii S. Aulchenko,Antonio Cao,Angelo Scuteri,David Schlessinger,Manuela Uda,Aimo Ruokonen,Marjo Riitta-Järvelin,Marjo Riitta-Järvelin,Dawn M. Waterworth,Peter Vollenweider,Leena Peltonen,Vincent Mooser,Gonçalo R. Abecasis,Nicholas J. Wareham,Robert Sladek,Philippe Froguel,Philippe Froguel,Richard M. Watanabe,James B. Meigs,Leif Groop,Michael Boehnke,Mark I. McCarthy,Jose C. Florez,Jose C. Florez,Inês Barroso +339 more
TL;DR: It is demonstrated that genetic studies of glycemic traits can identify type 2 diabetes risk loci, as well as loci containing gene variants that are associated with a modest elevation in glucose levels but are not associated with overt diabetes.
Journal ArticleDOI
A genome-wide association search for type 2 diabetes genes in African Americans.
Nichole D. Palmer,Caitrin W. McDonough,Pamela J. Hicks,B H Roh,M R Wing,S S An,Jessica M. Hester,Jessica N. Cooke,Meredith A. Bostrom,Megan E. Rudock,Matthew E. Talbert,Joshua P. Lewis,Assiamira Ferrara,Lingyi Lu,Julie T. Ziegler,Michèle M. Sale,Jasmin Divers,Daniel Shriner,Adebowale Adeyemo,Charles N. Rotimi,Ng Mcy.,Carl D. Langefeld,Barry I. Freedman,Donald W. Bowden,Benjamin F. Voight,Laura J. Scott,Valgerdur Steinthorsdottir,Andrew P. Morris,Christian Dina,Ryan P. Welch,Eleftheria Zeggini,Cornelia Huth,Yurii S. Aulchenko,Gudmar Thorleifsson,Laura J. McCulloch,Teresa Ferreira,Harald Grallert,Najaf Amin,Guanming Wu,Cristen J. Willer,Soumya Raychaudhuri,Steven A. McCarroll,Claudia Langenberg,O M Hofmann,Josée Dupuis,Lu Qi,A V Segrè,M. van Hoek,Pau Navarro,Kristin G. Ardlie,Beverley Balkau,Rafn Benediktsson,Amanda J. Bennett,Roza Blagieva,Eric Boerwinkle,Lori L. Bonnycastle,Kristina Bengtsson Boström,Bert Bravenboer,Suzannah Bumpstead,N P Burtt,Guillaume Charpentier,Peter S. Chines,Marilyn C. Cornelis,David Couper,Gabriel Crawford,Doney Asf.,Kathryn Elliott,A L Elliott,Michael R. Erdos,Caroline S. Fox,Christopher S. Franklin,Martha Ganser,Christian Gieger,Niels Grarup,Todd Green,Simon J. Griffin,C J Groves,Candace Guiducci,Samy Hadjadj,N Hassanali,C. Herder,Bo Isomaa,Anne U. Jackson,Johnson Prv.,Torben Jørgensen,Kao Whl.,N Klopp,Augustine Kong,Peter Kraft,Johanna Kuusisto,Torsten Lauritzen,Man Li,Aloysius G Lieverse,Cecilia M. Lindgren,Valeriya Lyssenko,Meghan L. Marré,Thomas Meitinger,Kristian Midthjell,Mario A. Morken,Narisu Narisu,P. M. Nilsson,Katharine R. Owen,Felicity Payne,Perry Jrb.,Petersen A-K.,Carl G. P. Platou,Christine Proença,Inga Prokopenko,Wolfgang Rathmann,N W Rayner,Neil R. Robertson,Ghislain Rocheleau,Michael Roden,Mike Sampson,Richa Saxena,B M Shields,Peter Shrader,Gunnar Sigurdsson,Thomas Sparsø,Klaus Strassburger,Heather M. Stringham,Qi Sun,Amy J. Swift,Barbara Thorand,Jean Tichet,Tiinamaija Tuomi,R. M. van Dam,T.W. van Haeften,T van Herpt,J. V. van Vliet-Ostaptchouk,G B Walters,Michael N. Weedon,Cisca Wijmenga,Jacqueline C. M. Witteman,Richard N. Bergman,Stéphane Cauchi,Francis S. Collins,Anna L. Gloyn,Ulf Gyllensten,Torben Hansen,Winston Hide,Graham A. Hitman,Albert Hofman,David J. Hunter,Kristian Hveem,Markku Laakso,Karen L. Mohlke,Andrew D. Morris,Palmer Cna.,Peter P. Pramstaller,Igor Rudan,Eric J.G. Sijbrands,Lincoln D. Stein,Jaakko Tuomilehto,A.G. Uitterlinden,M Walker,Nicholas J. Wareham,Richard M. Watanabe,Gonçalo R. Abecasis,Bernhard O. Boehm,Harry Campbell,Mark J. Daly,Andrew T. Hattersley,Frank B. Hu,James B. Meigs,James S. Pankow,Oluf Pedersen,Wichmann H-E.,Inês Barroso,Jose C. Florez,Timothy M. Frayling,Leif Groop,R Sladek,Unnur Thorsteinsdottir,James F. Wilson,Thomas Illig,Philippe Froguel,C M van Duijn,Kari Stefansson,David Altshuler,Michael Boehnke,Mark I. McCarthy,Nicole Soranzo,Eleanor Wheeler,Nicole L. Glazer,Nabila Bouatia-Naji,Reedik Mägi,Joshua C. Randall,Toby Johnson,Paul Elliott,Denis Rybin,Peter Henneman,Abbas Dehghan,Jouke-Jan Hottenga,Kijoung Song,Anuj Goel,Josephine M. Egan,Taina K. Lajunen,Alex S. F. Doney,Stavroula Kanoni,Christine Cavalcanti-Proença,Meena Kumari,Nicholas J. Timpson,Carina Zabena,Erik Ingelsson,Ping An,Jeffrey R. O'Connell,Jian'an Luan,Amanda F. Elliott,Rosa Maria Roccasecca,François Pattou,Praveen Sethupathy,Yavuz Ariyurek,Philip J. Barter,John Beilby,Yoav Ben-Shlomo,Sven Bergmann,Murielle Bochud,Amélie Bonnefond,Knut Borch-Johnsen,Yvonne Böttcher,Eric J. Brunner,Suzannah Bumpstead,Chen Y-Di.,Peter S. Chines,Robert Clarke,Coin Ljm.,Mark E. Cooper,Laura Crisponi,Day Inm.,de Geus Ejc.,Jérôme Delplanque,A C Fedson,Antje Fischer-Rosinsky,Nita G. Forouhi,R.R. Frants,MariaGrazia Franzosi,Pilar Galan,Mark O. Goodarzi,J. Graessler,Scott M. Grundy,R. Gwilliam,Göran Hallmans,Naomi Hammond,Xijing Han,Hartikainen A-L.,Caroline Hayward,Simon C. Heath,Serge Hercberg,Andrew A. Hicks,David R. Hillman,Aroon D. Hingorani,Jennie Hui,Joseph Hung,A. Jula,Marika Kaakinen,Jaakko Kaprio,Y A Kesaniemi,Mika Kivimäki,Beatrice Knight,Sini Koskinen,Peter Kovacs,Kirsten Ohm Kyvik,G M Lathrop,Debbie A Lawlor,O Le Bacquer,Cécile Lecoeur,Yun Li,Robert W. Mahley,Massimo Mangino,Alisa K. Manning,María Teresa Martínez-Larrad,Jarred B. McAteer,Ruth McPherson,Christine Meisinger,David Melzer,David Meyre,B. D. Mitchell,Sutapa Mukherjee,Silvia Naitza,Matt J. Neville,B.A. Oostra,Marco Orrù,Ruth E. Pakyz,Giuseppe Paolisso,C. Pattaro,D. Pearson,John F. Peden,Nancy L. Pedersen,M. Perola,Pfeiffer Afh.,Irene Pichler,Ozren Polašek,Danielle Posthuma,Simon C. Potter,Anneli Pouta,M. A. Province,Bruce M. Psaty,Kenneth Rice,Samuli Ripatti,F. Rivadeneira,Olov Rolandsson,A. Sandbaek,M. S. Sandhu,Serena Sanna,Avan Aihie Sayer,Paul Scheet,Udo Seedorf,Stephen J. Sharp,Beverley M. Shields,Sijbrands Ejg.,Angela Silveira,Laila Simpson,Andrew B. Singleton,Nicholas L. Smith,Ulla Sovio,A J Swift,H E Syddall,Syvänen A-C.,Toshiko Tanaka,Anke Tönjes,Andre G. Uitterlinden,K W van Dijk,Dhiraj Varma,Sophie Visvikis-Siest,Veronique Vitart,Nicole Vogelzangs,Gerard Waeber,P J Wagner,Andrew Walley,Kim L. Ward,Hugh Watkins,Sarah H. Wild,Gonneke Willemsen,Witteman Jcm.,Yarnell Jwg.,Diana Zelenika,Björn Zethelius,Guangju Zhai,Jing Hua Zhao,M. C. Zillikens,Ingrid B. Borecki,Loos Rjf.,Pierre Meneton,Magnusson Pke.,David M. Nathan,Gordon H. Williams,Kaisa Silander,Veikko Salomaa,George Davey Smith,Stefan R. Bornstein,Peter Schwarz,Jochen Spranger,F Karpe,Alan R. Shuldiner,Cyrus Cooper,George Dedoussis,Manuel Serrano-Ríos,Lars Lind,Lyle J. Palmer,Paul W. Franks,Shah Ebrahim,Michael Marmot,Alan F. Wright,Michael Stumvoll,Anders Hamsten,Thomas A. Buchanan,Timo T. Valle,Jerome I. Rotter,David S. Siscovick,Penninx Bwjh.,Dorret I. Boomsma,Panos Deloukas,Tim D. Spector,Luigi Ferrucci,Anyuan Cao,Angelo Scuteri,David Schlessinger,Manuela Uda,Aimo Ruokonen,Jarvelin M-R.,Dawn M. Waterworth,Peter Vollenweider,Leena Peltonen,Vincent Mooser +384 more
TL;DR: It is suggested that multiple loci underlie T2DM susceptibility in the African-American population and that these loci are distinct from those identified in other ethnic populations.
Journal ArticleDOI
Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge
Richa Saxena,Richa Saxena,Claudia Langenberg,Toshiko Tanaka,Toshiko Tanaka,James S. Pankow,Peter Vollenweider,Valeriya Lyssenko,Nabila Bouatia-Naji,Josée Dupuis,Anne U. Jackson,W. H. Linda Kao,Man Li,Nicole L. Glazer,Alisa K. Manning,Jian Anluan,Heather M. Stringham,Inga Prokopenko,Toby Johnson,Niels Grarup,Trine Welløv Boesgaard,Cécile Lecoeur,Peter Shrader,Jeffrey R. O'Connell,Erik Ingelsson,Erik Ingelsson,David Couper,Kenneth Rice,Kijoung Song,Camilla H. Andreasen,Christian Dina,Anna Köttgen,Olivier Le Bacquer,François Pattou,Jalal Taneera,Valgerdur Steinthorsdottir,Denis Rybin,Kristin Ardlie,Mike Sampson,Lu Qi,Mandy van Hoek,Michael N. Weedon,Yurii S. Aulchenko,Benjamin F. Voight,Benjamin F. Voight,Harald Grallert,Beverley Balkau,Richard N. Bergman,Suzette J. Bielinski,Amélie Bonnefond,Lori L. Bonnycastle,Knut Borch-Johnsen,Yvonne Böttcher,Eric J. Brunner,Thomas A. Buchanan,Suzannah Bumpstead,Christine Cavalcanti-Proença,Guillaume Charpentier,Yii-Der Ida Chen,Peter S. Chines,Francis S. Collins,Marilyn C. Cornelis,Gabriel Crawford,Jérôme Delplanque,Alex S. F. Doney,Josephine M. Egan,Michael R. Erdos,Mathieu Firmann,Nita G. Forouhi,Caroline S. Fox,Caroline S. Fox,Mark O. Goodarzi,J. Graessler,Aroon D. Hingorani,Bo Isomaa,Torben Jørgensen,Mika Kivimäki,Peter Kovacs,Knut Krohn,Meena Kumari,Torsten Lauritzen,Claire Levy-Marchal,Vladimir Mayor,Jarred B. McAteer,Jarred B. McAteer,David Meyre,Braxton D. Mitchell,Karen L. Mohlke,Mario A. Morken,Narisu Narisu,Colin N. Apalmer,Ruth E. Pakyz,Laura Pascoe,Felicity Payne,Daniel S. Pearson,Wolfgang Rathmann,Annelli Sandbæk,Avan Aihie Sayer,Laura J. Scott,Stephen J. Sharp,Eric J.G. Sijbrands,Andrew B. Singleton,David S. Siscovick,Nicholas L. Smith,Nicholas L. Smith,Thomas Sparsø,Amy J. Swift,Holly E. Syddall,Gudmar Thorleifsson,Anke Tönjes,Anke Tönjes,Tiinamaija Tuomi,Jaakko Tuomilehto,Valle Tt,Gerard Waeber,Andrew Walley,Dawn M. Waterworth,Eleftheria Zeggini,Jing Hua Zhao,Thomas Illig,H.-Erich Wichmann,H.-Erich Wichmann,James F. Wilson,Cornelia M. van Duijn,Frank B. Hu,Frank B. Hu,Andrew D. Morris,Timothy M. Frayling,Timothy M. Frayling,Andrew T. Hattersley,Andrew T. Hattersley,Unnur Thorsteinsdottir,Unnur Thorsteinsdottir,Kari Stefansson,Kari Stefansson,Peter M. Nilsson,Ann-Christine Syvänen,Alan R. Shuldiner,Alan R. Shuldiner,Mark Walker,Stefan R. Bornstein,Peter Schwarz,Gordon H. Williams,David M. Nathan,Johanna Kuusisto,Markku Laakso,Cyrus Cooper,Michael Marmot,Luigi Ferrucci,Vincent Mooser,Michael Stumvoll,Ruth J. F. Loos,David Altshuler,David Altshuler,Bruce M. Psaty,Jerome I. Rotter,Eric Boerwinkle,Torben Hansen,Torben Hansen,Oluf Pedersen,Oluf Pedersen,Jose C. Florez,Jose C. Florez,Mark I. McCarthy,Mark I. McCarthy,Michael Boehnke,Inês Barroso,Robert Sladek,Philippe Froguel,Philippe Froguel,James B. Meigs,Leif Groop,Nicholas J. Wareham,Richard M. Watanabe +173 more
TL;DR: A meta-analysis of nine genome-wide association studies and a follow-up of 29 independent loci found three newly implicated loci to be associated with type 2 diabetes: GIPR, ADCY5 and VPS13C.
Journal ArticleDOI
The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study
Thomas W. Winkler,Anne E. Justice,Mariaelisa Graff,Llilda Barata,Mary F. Feitosa,Su H. Chu,Jacek Czajkowski,Tõnu Esko,Tove Fall,Tuomas O. Kilpeläinen,Yingchang Lu,Reedik Mägi,Evelin Mihailov,Tune H. Pers,Sina Rüeger,Alexander Teumer,Georg Ehret,Teresa Ferreira,Nancy L. Heard-Costa,Juha Karjalainen,Vasiliki Lagou,Anubha Mahajan,Michael D. Neinast,Inga Prokopenko,Jeannette Simino,Tanya M. Teslovich,Rick Jansen,Harm-Jan Westra,Charles C. White,Devin Absher,Tarunveer S. Ahluwalia,Shafqat Ahmad,Eva Albrecht,Alexessander Couto Alves,Jennifer L. Bragg-Gresham,Anton J. M. de Craen,Joshua C. Bis,Amélie Bonnefond,Gabrielle Boucher,Gemma Cadby,Yu-Ching Cheng,Charleston W. K. Chiang,Graciela Delgado,Ayse Demirkan,Nicole Dueker,Niina Eklund,Gudny Eiriksdottir,Joel Eriksson,Bjarke Feenstra,Krista Fischer,Francesca Frau,Tessel E. Galesloot,Frank Geller,Anuj Goel,Mathias Gorski,Tanja B. Grammer,Stefan Gustafsson,Saskia Haitjema,Jouke-Jan Hottenga,Jennifer E. Huffman,Anne U. Jackson,Kevin B. Jacobs,Åsa Johansson,Marika Kaakinen,Marcus E. Kleber,Jari Lahti,Irene Mateo Leach,Benjamin Lehne,Youfang Liu,Ken Sin Lo,Mattias Lorentzon,Jian'an Luan,Pamela A. F. Madden,Massimo Mangino,Barbara McKnight,Carolina Medina-Gomez,Keri L. Monda,May E. Montasser,Gabriele Müller,Martina Müller-Nurasyid,Ilja M. Nolte,Kalliope Panoutsopoulou,Laura Pascoe,Lavinia Paternoster,Nigel W. Rayner,Frida Renström,Federica Rizzi,Lynda M. Rose,Kathy Ryan,Perttu Salo,Serena Sanna,Hubert Scharnagl,Jianxin Shi,Albert V. Smith,Lorraine Southam,Alena Stančáková,Valgerdur Steinthorsdottir,Rona J. Strawbridge,Yun Ju Sung,Ioanna Tachmazidou,Toshiko Tanaka,Gudmar Thorleifsson,Stella Trompet,Natalia Pervjakova,Jonathan Tyrer,Liesbeth Vandenput,Sander W. van der Laan,Nathalie van der Velde,Jessica van Setten,Jana V. van Vliet-Ostaptchouk,Niek Verweij,Efthymia Vlachopoulou,Lindsay L. Waite,Sophie R. Wang,Zhaoming Wang,Sarah H. Wild,Christina Willenborg,James F. Wilson,Andrew Wong,Jian Yang,Loic Yengo,Laura M. Yerges-Armstrong,Lei Yu,Weihua Zhang,Jing Hua Zhao,Ehm A. Andersson,Stephan J. L. Bakker,Damiano Baldassarre,Karina Banasik,Matteo Barcella,Cristina Barlassina,Claire Bellis,Paola Benaglio,John Blangero,Matthias Blüher,Fabrice Bonnet,Lori L. Bonnycastle,Heather A. Boyd,Marcel Bruinenberg,Aron S. Buchman,Harry Campbell,Yii-Der Ida Chen,Peter S. Chines,Simone Claudi-Boehm,John B. Cole,Francis S. Collins,Eco J. C. de Geus,Lisette C. P. G. M. de Groot,Maria Dimitriou,Jubao Duan,Stefan Enroth,Elodie Eury,Aliki-Eleni Farmaki,Nita G. Forouhi,Nele Friedrich,Pablo V. Gejman,Bruna Gigante,Nicola Glorioso,Alan S. Go,Omri Gottesman,Jürgen Gräßler,Harald Grallert,Niels Grarup,Yu Mei Gu,Linda Broer,Annelies C. Ham,Torben Hansen,Tamara B. Harris,Catharina A. Hartman,Maija Hassinen,Nicholas D. Hastie,Andrew T. Hattersley,Andrew C. Heath,Anjali K. Henders,Dena G. Hernandez,Hans L. Hillege,Oddgeir L. Holmen,Kees Hovingh,Jennie Hui,Lise Lotte N. Husemoen,Nina Hutri-Kähönen,Pirro G. Hysi,Thomas Illig,Philip L. De Jager,Shapour Jalilzadeh,Torben Jørgensen,J. Wouter Jukema,Markus Juonala,Stavroula Kanoni,Maria Karaleftheri,Kay-Tee Khaw,Leena Kinnunen,Steven J. Kittner,Wolfgang Koenig,Ivana Kolcic,Peter Kovacs,Nikolaj T. Krarup,Wolfgang Kratzer,Janine Krüger,Diana Kuh,Meena Kumari,Theodosios Kyriakou,Claudia Langenberg,Lars Lannfelt,Chiara Lanzani,Vaneet Lotay,Lenore J. Launer,Karin Leander,Jaana Lindström,Allan Linneberg,Yan Ping Liu,Stéphane Lobbens,Robert Luben,Valeriya Lyssenko,Satu Männistö,Patrik K. E. Magnusson,Wendy L. McArdle,Cristina Menni,Sigrun Merger,Lili Milani,Grant W. Montgomery,Andrew P. Morris,Narisu Narisu,Mari Nelis,Ken K. Ong,Aarno Palotie,Louis Pérusse,Irene Pichler,Maria Grazia Pilia,Anneli Pouta,Myriam Rheinberger,Rasmus Ribel-Madsen,Marcus Richards,Kenneth Rice,Treva Rice,Carlo Rivolta,Veikko Salomaa,Alan R. Sanders,Mark A. Sarzynski,Salome Scholtens,Robert A. Scott,William R. Scott,Sylvain Sebert,Sebanti Sengupta,Bengt Sennblad,Thomas Seufferlein,Angela Silveira,P. Eline Slagboom,Jan Smit,Thomas Sparsø,Kathleen Stirrups,Ronald P. Stolk,Heather M. Stringham,Morris A. Swertz,Amy J. Swift,Ann-Christine Syvänen,Sian Tsung Tan,Barbara Thorand,Anke Tönjes,Angelo Tremblay,Emmanouil Tsafantakis,Peter J. van der Most,Uwe Völker,Marie-Claude Vohl,Judith M. Vonk,Melanie Waldenberger,Ryan W. Walker,Roman Wennauer,Elisabeth Widen,Gonneke Willemsen,Tom Wilsgaard,Alan F. Wright,M. Carola Zillikens,Suzanne C. van Dijk,Natasja M. van Schoor,Folkert W. Asselbergs,Paul I.W. de Bakker,Jacques S. Beckmann,John Beilby,David A. Bennett,Richard N. Bergman,Sven Bergmann,Carsten A. Böger,Bernhard O. Boehm,Eric Boerwinkle,Dorret I. Boomsma,Stefan R. Bornstein,Erwin P. Bottinger,Claude Bouchard,John C. Chambers,Stephen J. Chanock,Daniel I. Chasman,Francesco Cucca,Daniele Cusi,George Dedoussis,Jeanette Erdmann,Johan G. Eriksson,Denis A. Evans,Ulf de Faire,Martin Farrall,Luigi Ferrucci,Ian Ford,Lude Franke,Paul W. Franks,Philippe Froguel,Ron T. Gansevoort,Christian Gieger,Henrik Grönberg,Vilmundur Gudnason,Ulf Gyllensten,Per Hall,Anders Hamsten,Pim van der Harst,Caroline Hayward,Markku Heliövaara,Christian Hengstenberg,Andrew A. Hicks,Aroon D. Hingorani,Albert Hofman,Frank B. Hu,Heikki V. Huikuri,Kristian Hveem,Alan L. James,Joanne M. Jordan,Antti Jula,Mika Kähönen,Eero Kajantie,Sekar Kathiresan,Lambertus A. Kiemeney,Mika Kivimäki,Paul Knekt,Heikki A. Koistinen,Jaspal S. Kooner,Seppo Koskinen,Johanna Kuusisto,Winfried Maerz,Nicholas G. Martin,Markku Laakso,Timo A. Lakka,Terho Lehtimäki,Guillaume Lettre,Douglas F. Levinson,Lars Lind,Marja-Liisa Lokki,Pekka Mäntyselkä,Mads Melbye,Andres Metspalu,Braxton D. Mitchell,Frans L. Moll,Jeffrey C. Murray,Arthur W. Musk,Markku S. Nieminen,Inger Njølstad,Claes Ohlsson,Albertine J. Oldehinkel,Ben A. Oostra,Lyle J. Palmer,James S. Pankow,Gerard Pasterkamp,Nancy L. Pedersen,Oluf Pedersen,Brenda W.J.H. Penninx,Markus Perola,Annette Peters,Ozren Polasek,Peter P. Pramstaller,Bruce M. Psaty,Lu Qi,Thomas Quertermous,Olli T. Raitakari,Tuomo Rankinen,Rainer Rauramaa,Paul M. Ridker,John D. Rioux,Fernando Rivadeneira,Jerome I. Rotter,Igor Rudan,Hester M. den Ruijter,Juha Saltevo,Naveed Sattar,Heribert Schunkert,Peter Schwarz,Alan R. Shuldiner,Juha Sinisalo,Harold Snieder,Thorkild I. A. Sørensen,Tim D. Spector,Jan A. Staessen,Bandinelli Stefania,Unnur Thorsteinsdottir,Michael Stumvoll,Jean-Claude Tardif,Elena Tremoli,Jaakko Tuomilehto,André G. Uitterlinden,Matti Uusitupa,André L. M. Verbeek,Sita H. Vermeulen,Jorma Viikari,Veronique Vitart,Henry Völzke,Peter Vollenweider,Gérard Waeber,Mark Walker,Henri Wallaschofski,Nicholas J. Wareham,Hugh Watkins,Eleftheria Zeggini,Aravinda Chakravarti,Deborah J. Clegg,L. Adrienne Cupples,Penny Gordon-Larsen,Cashell E. Jaquish,Dabeeru C. Rao,Gonçalo R. Abecasis,Themistocles L. Assimes,Inês Barroso,Sonja I. Berndt,Michael Boehnke,Panos Deloukas,Caroline S. Fox,Leif Groop,David J. Hunter,Erik Ingelsson,Robert C. Kaplan,Mark I. McCarthy,Karen L. Mohlke,Jeffrey R. O'Connell,David Schlessinger,David P. Strachan,Kari Stefansson,Cornelia M. van Duijn,Joel N. Hirschhorn,Cecilia M. Lindgren,Iris M. Heid,Kari E. North,Ingrid B. Borecki,Zoltán Kutalik,Ruth J. F. Loos +438 more
TL;DR: In this paper, the authors performed meta-analyses of 114 studies with genome-wide chip and/or Metabochip data by the Genetic Investigation of Anthropometric Traits (GIANT) Consortium.
Journal ArticleDOI
Dysfunction of lipid sensor GPR120 leads to obesity in both mouse and human
Atsuhiko Ichimura,Akira Hirasawa,Odile Poulain-Godefroy,Odile Poulain-Godefroy,Amélie Bonnefond,Amélie Bonnefond,Takafumi Hara,Loic Yengo,Loic Yengo,Ikuo Kimura,Audrey Leloire,Audrey Leloire,Ning Liu,Keiko Iida,Hélène Choquet,Hélène Choquet,Philippe Besnard,Cécile Lecoeur,Cécile Lecoeur,Sidonie Vivequin,Sidonie Vivequin,Kumiko Ayukawa,Masato Takeuchi,Kentaro Ozawa,Maithé Tauber,Claudio Maffeis,Anita Morandi,Anita Morandi,Raffaella Buzzetti,Paul Elliott,Anneli Pouta,Marjo-Riitta Järvelin,Marjo-Riitta Järvelin,Antje Körner,Wieland Kiess,Marie Pigeyre,Roberto Caiazzo,Wim Van Hul,Luc Van Gaal,Fritz F. Horber,Beverley Balkau,Claire Levy-Marchal,Konstantinos Rouskas,Konstantinos Rouskas,Konstantinos Rouskas,Anastasia Kouvatsi,Johannes Hebebrand,Anke Hinney,André Scherag,François Pattou,David Meyre,David Meyre,David Meyre,Taka-aki Koshimizu,Isabelle Wolowczuk,Isabelle Wolowczuk,Gozoh Tsujimoto,Philippe Froguel,Philippe Froguel,Philippe Froguel +59 more
TL;DR: This study demonstrates that the lipid sensor GPR120 has a key role in sensing dietary fat and, therefore, in the control of energy balance in both humans and rodents.