N
Nicolas Simon
Researcher at Aix-Marseille University
Publications - 165
Citations - 3097
Nicolas Simon is an academic researcher from Aix-Marseille University. The author has contributed to research in topics: Population & Pharmacokinetics. The author has an hindex of 31, co-authored 158 publications receiving 2612 citations. Previous affiliations of Nicolas Simon include University of the Mediterranean.
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Vancomycin: a review of population pharmacokinetic analyses.
TL;DR: It is suggested that external evaluation should be the first step in a pharmacokinetic analysis of vancomycin rather than describing a new model, and a sensitive liquid chromatography-tandem mass spectrometry method could be used and new covariates such as cardiac output or possible renal transporters could be tested.
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Off-Label Prescribing of Antipsychotics in Adults, Children and Elderly Individuals: A Systematic Review of Recent Prescription Trends.
Louise Carton,Olivier Cottencin,Maryse Lapeyre-Mestre,Pierre-Alexis Geoffroy,Jonathan Favre,Nicolas Simon,Régis Bordet,Benjamin Rolland +7 more
TL;DR: OLP is often used in cases of therapeutic dead-ends or for specific disorders with few or no currently approved medications, however, other OLP practices only reflect temporary prescription trends for mild symptoms, which may induce safety concerns.
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Vemurafenib for Refractory Multisystem Langerhans Cell Histiocytosis in Children: An International Observational Study
Jean Donadieu,Islam Amine Larabi,Mathilde Tardieu,Johannes Visser,Caroline Hutter,Elena Sieni,Nabil Kabbara,Mohamed Barkaoui,Jean Miron,François Chalard,Paul Milne,Julien Haroche,Fleur Cohen,Zofia Hélias-Rodzewicz,Nicolas Simon,Mathilde Jehanne,Alexandra Kolenova,Anne Pagnier,Nathalie Aladjidi,Pascale Schneider,Geneviève Plat,Anne Lutun,Anne Sonntagbauer,Thomas Lehrnbecher,Alina Ferster,Viktoria Efremova,Martina Ahlmann,Laurence Blanc,James Nicholson,Anne Lambilliote,Houda Boudiaf,Andrej Lissat,Karel Svojgr,Fanette Bernard,Sarah Elitzur,Michal Golan,Dmitriy Evseev,Michael Maschan,Ahmed Idbaih,Olga Slater,Milen Minkov,Valérie Taly,Matthew Collin,Jean-Claude Alvarez,Jean-François Emile,Sébastien Héritier +45 more
TL;DR: VMF seemed safe and effective in children with refractory BRAFV600E-positive LCH and none of the various empirical therapies used for maintenance could eradicate the BRAFv600E clone.
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Expression of the genetic variants of human alpha-1-acid glycoprotein in cancer.
TL;DR: The results show that AAG plasma concentrations are increased in these types of cancers and that changes in the expression of the genetic variants of AAG could also occur according to the type of cancer.
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Biologic rhythms and Parkinson's disease: a chronopharmacologic approach to considering fluctuations in function.
TL;DR: Diurnal variations of clinical, biologic, or experimental factors described with Parkinson's disease are reviewed to review diurnal changes of circadian rhythms in dopaminergic systems as well as possible daily fluctuations in kinetics of drug treatments.