O
Odilia Popanda
Researcher at German Cancer Research Center
Publications - 82
Citations - 3259
Odilia Popanda is an academic researcher from German Cancer Research Center. The author has contributed to research in topics: DNA repair & Breast cancer. The author has an hindex of 33, co-authored 81 publications receiving 3013 citations. Previous affiliations of Odilia Popanda include Epigenomics AG.
Papers
More filters
Journal ArticleDOI
Specific combinations of DNA repair gene variants and increased risk for non-small cell lung cancer
Odilia Popanda,Torsten Schattenberg,Chi Tai Phong,Dorota Butkiewicz,Angela Risch,Lutz Edler,Klaus Kayser,Hendrik Dienemann,Volker Schulz,Peter Drings,Helmut Bartsch,Peter Schmezer +11 more
TL;DR: Lung cancer risk is only moderately increased by single DNA repair gene variants investigated but it is considerably enhanced by specific combinations of variant alleles, especially in patients with SCC.
Journal ArticleDOI
Association between Polymorphisms in the DNA Repair Genes, XRCC1, APE1, and XPD and Acute Side Effects of Radiotherapy in Breast Cancer Patients
Jenny Chang-Claude,Odilia Popanda,Xiang-Lin Tan,Silke Kropp,Irmgard Helmbold,Dietrich von Fournier,Wulf Haase,Marie Luise Sautter-Bihl,Frederik Wenz,Peter Schmezer,Christine B. Ambrosone +10 more
TL;DR: The XRCC1 399Gln or APE1 148Glu alleles may be protective against the development of acute side effects after radiotherapy in patients with normal weight, as well as compared with homozygote carriers of the wild-type allele in both genes.
Journal ArticleDOI
Modulation of DNA polymerases alpha, delta and epsilon by lactate dehydrogenase and 3-phosphoglycerate kinase
TL;DR: The effects of phosphorylated lactate dehydrogenase and 3-phosphoglycerate kinase on UV-induced DNA repair, using permeabilized human fibroblasts and in vitro DNA synthesis catalyzed by purified DNA polymerases α, δ, and e from proliferating rat liver are studied.
Journal ArticleDOI
Personal characteristics, therapy modalities and individual DNA repair capacity as predictive factors of acute skin toxicity in an unselected cohort of breast cancer patients receiving radiotherapy.
Dorothee Twardella,Odilia Popanda,Irmgard Helmbold,Reinhard Ebbeler,Axel Benner,Dietrich von Fournier,Wulf Haase,Marie Luise Sautter-Bihl,Frederik Wenz,Peter Schmezer,Jenny Chang-Claude +10 more
TL;DR: Higher BMI is predictive of acute skin toxicity, however, individual repair parameters as determined by the alkaline comet assay are not informative enough.
Journal ArticleDOI
International Lung Cancer Consortium: Pooled Analysis of Sequence Variants in DNA Repair and Cell Cycle Pathways
Rayjean Hung,Rayjean Hung,David C. Christiani,Angela Risch,Odilia Popanda,Aage Haugen,Shan Zienolddiny,Simone Benhamou,Simone Benhamou,Christine Bouchardy,Qing Lan,Margaret R. Spitz,H.-Erich Wichmann,Loic LeMarchand,Paolo Vineis,Giuseppe Matullo,Chikako Kiyohara,Zuo-Feng Zhang,Benhnaz Pezeshki,Curtis C. Harris,Leah E. Mechanic,Adeline Seow,Daniel P.K. Ng,Neonila Szeszenia-Dabrowska,David Zaridze,Jolanta Lissowska,Peter Rudnai,Eleonora Fabianova,Dana Mates,Lenka Foretova,Vladimir Janout,Vladimir Bencko,Neil E. Caporaso,Chu Chen,Eric J. Duell,Gary E. Goodman,John K. Field,Richard S. Houlston,Yun Chul Hong,Maria Teresa Landi,Philip Lazarus,Joshua E. Muscat,John R. McLaughlin,Ann G. Schwartz,Hongbing Shen,Isabelle Stücker,Kazuo Tajima,Keitaro Matsuo,Michael J. Thun,Ping Yang,John K. Wiencke,Angeline S. Andrew,Stéphanie Monnier,Paolo Boffetta,Paul Brennan +54 more
TL;DR: A pooled analysis of genetic variants in DNA repair pathways found four variants to be weakly associated with lung cancer risk with borderline significance and future priorities of International Lung Cancer Consortium include coordinated genotyping and multistage validation for ongoing genome-wide association studies.