O
Olli Teronen
Researcher at University of Helsinki
Publications - 54
Citations - 2924
Olli Teronen is an academic researcher from University of Helsinki. The author has contributed to research in topics: Matrix metalloproteinase & Periodontitis. The author has an hindex of 32, co-authored 53 publications receiving 2824 citations. Previous affiliations of Olli Teronen include University of Tampere & Helsinki University Central Hospital.
Papers
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Journal ArticleDOI
Activation of Type IV Procollagenases by Human Tumor-associated Trypsin-2*
Timo Sorsa,Tuula Salo,Erkki Koivunen,Jaana Tyynelä,Yrjö T. Konttinen,Ulrich Bergmann,Ari Tuuttila,E Niemi,Olli Teronen,Pia Heikkilä,Harald Tschesche,Jari Leinonen,Sirpa Osman,Ulf-Håkan Stenman +13 more
TL;DR: The ability of human tumor cell-derived trypsin-2 to activate latent MMPs suggests a role for trypsIn-2 in initiating the proteinase cascade that mediates tumor invasion and metastasis formation.
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MMP inhibition and downregulation by bisphosphonates.
Olli Teronen,Pia Heikkilä,Yrjö T. Konttinen,Minna Laitinen,Tuula Salo,Roeland Hanemaaijer,Anneli Teronen,Päivi Maisi,Timo Sorsa +8 more
TL;DR: It is discovered that various matrix metalloproteinases (MMPs) are inhibited in vitro by several bisphosphonates, which has the potential to become one of the main MMP‐inhibitors for MMP-related human soft and hard tissue‐destructive diseases in the near future.
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Effects of tetracyclines on neutrophil, gingival, and salivary collagenases. A functional and western-blot assessment with special reference to their cellular sources in periodontal diseases.
Timo Sorsa,Y. Ding,Tuula Salo,Anneli Lauhio,Olli Teronen,Tuula Ingman,Haruo Ohtani,Noriaki Andoh,Satoshi Takeha,Yrjö T. Konttinen +9 more
TL;DR: The key role of PMN-MMPs in periodontitis is extended, and the activities of these PMN MMPs can be inhibited directly by therapeutic levels of DOXY, providing evidence for noncompetitive inhibition.
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The Effects of MMP Inhibitors on Human Salivary MMP Activity and Caries Progression in Rats
TL;DR: It is suggested that MMPs have an important role in dentin caries pathogenesis, and that CMT-3 and zoledronate inhibitors may prove to be useful in the prevention of caries progression.
Journal ArticleDOI
Expression and induction of collagenases (MMP-8 and -13) in plasma cells associated with bone-destructive lesions.
J Wahlgren,Päivi Maisi,Timo Sorsa,Meeri Sutinen,Taina Tervahartiala,Emma Pirilä,Olli Teronen,Jarkko Hietanen,Leo Tjäderhane,Tuula Salo +9 more
TL;DR: It is concluded that plasma cell MMP‐13 has a particularly important role in benign and malignant bone‐destructive lesions in chronic inflammation and neoplastic growth.