O
Otto C. Boerman
Researcher at Radboud University Nijmegen
Publications - 358
Citations - 17532
Otto C. Boerman is an academic researcher from Radboud University Nijmegen. The author has contributed to research in topics: Radioimmunotherapy & In vivo. The author has an hindex of 66, co-authored 355 publications receiving 15882 citations. Previous affiliations of Otto C. Boerman include Radboud University Nijmegen Medical Centre.
Papers
More filters
Journal ArticleDOI
Imaging of Human Epidermal Growth Factor Receptor Type 2 Expression with 18F-Labeled Affibody Molecule ZHER2:2395 in a Mouse Model for Ovarian Cancer
Sandra Heskamp,Peter Laverman,Daniel Rosik,Frederic Boschetti,Winette T. A. van der Graaf,Wim J.G. Oyen,Hanneke W. M. van Laarhoven,Vladimir Tolmachev,Otto C. Boerman +8 more
TL;DR: 18F-NOTA-ZHER2:2395 is a promising new imaging agent for HER2 expression in tumors, and further research is needed to determine whether this technique can be used for patient selection for Her2-targeted therapy.
Journal Article
Pretargeting of renal cell carcinoma: improved tumor targeting with a bivalent chelate.
Otto C. Boerman,Marion H. G. C. Kranenborg,Egbert Oosterwijk,Gary L. Griffiths,William J. McBride,Wim J.G. Oyen,Mirjam de Weijert,J.C. Oosterwijk-Wakka,Hans J. Hansen,Frans H.M. Corstens +9 more
TL;DR: Two studies indicate that the use of bivalent chelates can very effectively optimize two-step targeting of tumors with bsmAbs and indicate that this approach could optimize radioimmunotherapy.
Journal ArticleDOI
Early identification of antigen-specific immune responses in vivo by [18F]-labeled 3'-fluoro-3'-deoxy-thymidine ([18F]FLT) PET imaging.
Erik H.J.G. Aarntzen,Mangala Srinivas,Johannes H. W. de Wilt,Joannes F M Jacobs,W. Joost Lesterhuis,Albert D. Windhorst,Esther G.C. Troost,Johannes J. Bonenkamp,Michelle M. van Rossum,Willeke A. M. Blokx,Roel Mus,Otto C. Boerman,Cornelis J. A. Punt,Carl G. Figdor,Wim J.G. Oyen,I. Jolanda M. de Vries +15 more
TL;DR: [18F]FLT PET offers a sensitive tool to study the kinetics, localization, and involvement of lymphocyte subsets in response to vaccination and allows for early discrimination of responding from nonresponding patients in anti-cancer vaccination and aid physicians in individualized decisionmaking.
Journal ArticleDOI
Comparative immunohistochemical study of four monoclonal antibodies directed against ovarian carcinoma-associated antigens
TL;DR: The monoclonal antibodies OC 125, OV-TL 3, MOv 18, and Ov-TL 23, which are directed against distinct ovarian carcinoma-associated antigens, are assessed in the present study for their diagnostic value.
Journal ArticleDOI
Innovations in Radiotherapy Planning of Head and Neck Cancers: Role of PET
Esther G.C. Troost,Dominic A.X. Schinagl,Johan Bussink,Otto C. Boerman,Albert J. van der Kogel,Wim J.G. Oyen,Johannes H.A.M. Kaanders +6 more
TL;DR: The current role of PET and perspectives on its future use for selection and delineation of radiotherapy target volumes and for biologic characterization of this tumor entity are described.