O
Otto C. Boerman
Researcher at Radboud University Nijmegen
Publications - 358
Citations - 17532
Otto C. Boerman is an academic researcher from Radboud University Nijmegen. The author has contributed to research in topics: Radioimmunotherapy & In vivo. The author has an hindex of 66, co-authored 355 publications receiving 15882 citations. Previous affiliations of Otto C. Boerman include Radboud University Nijmegen Medical Centre.
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Journal ArticleDOI
Functionalization of multilayered DNA-coatings with bone morphogenetic protein 2
van den Jjjp Beucken,XF Walboomers,Otto C. Boerman,Mrj Matthijn Vos,Najm Nico Sommerdijk,Tohru Hayakawa,Tadao Fukushima,Yoshio Okahata,Rjm Roeland Nolte,Rjm Roeland Nolte,John A. Jansen +10 more
TL;DR: The results demonstrate the feasibility of multilayered DNA-coatings to be functionalized by embedding BMP-2 according to three different loading modalities: superficial (s), deep (d), and double-layer (dl).
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PET Radioimmunoscintigraphy of Renal Cell Cancer Using 89Zr-Labeled cG250 Monoclonal Antibody in Nude Rats
Adrienne H. Brouwers,Iris Verel,Julliëtte E.M. van Eerd,Gerard W. M. Visser,Martijn S. Steffens,Egbert Oosterwijk,Frans H.M. Corstens,Wim J.G. Oyen,Guus A.M.S. van Dongen,Otto C. Boerman +9 more
TL;DR: Scintigraphic tumor imaging using chimeric moAb G250 labeled with 89Zr (immuno-PET) or 111In (RIS), and [18F]FDG-(PET) was explored in rats with s.c. renal cell carcinoma (RCC) tumors, and relatively small tumors could be visualized, even without a dedicated PET camera for small animals.
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Caffeine Prevents Protection in Two Human Models of Ischemic Preconditioning
Niels P. Riksen,Zhigang Zhou,Wim J.G. Oyen,Rogier Jaspers,Bart P. Ramakers,Rene M.H.J. Brouwer,Otto C. Boerman,Neil Steinmetz,Paul Smits,Gerard A. Rongen +9 more
TL;DR: Caffeine abolishes IP in 2 human models at a dose equivalent to the drinking of 2 to 4 cups of coffee, and in vitro, IP improved post-ischemic functional recovery in the control group, but not in the caffeine group.
Journal Article
Absolute organ activity estimated by five different methods of background correction.
TL;DR: Even though quantitative SPECT is the most rigorous method for activity quantification in conditions of low organ-to-background activity concentration ratio, planar scintigraphy can be applied accurately if appropriate attention is paid to background correction.
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Radio-labeled receptor-binding peptides: A new class of radiopharmaceuticals
TL;DR: Radio-labeled receptor-binding peptides have emerged as an important class of radiopharmaceuticals, and peptides binding to these receptors can be used to visualize tumor lesions scintigraphically and for peptide-receptor radionuclide therapy.