O
Otto C. Boerman
Researcher at Radboud University Nijmegen
Publications - 358
Citations - 17532
Otto C. Boerman is an academic researcher from Radboud University Nijmegen. The author has contributed to research in topics: Radioimmunotherapy & In vivo. The author has an hindex of 66, co-authored 355 publications receiving 15882 citations. Previous affiliations of Otto C. Boerman include Radboud University Nijmegen Medical Centre.
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Journal ArticleDOI
Strain Differences Determine the Suitability of Animal Models for Noninvasive In Vivo Beta Cell Mass Determination with Radiolabeled Exendin.
Stefanie Willekens,Lieke Joosten,Otto C. Boerman,Alexander Balhuizen,Decio L. Eizirik,Martin Gotthardt,Maarten Brom +6 more
TL;DR: Brown Norway rats showed beta-cell-specific tracer accumulation and favorable pancreas-to-background ratios for noninvasive BCM determination and are suggested as a more adequate model for humans.
Journal ArticleDOI
Receptor Binding Ligands to Image Infection
TL;DR: Radiolabeled antibiotics and antimicrobial peptides are promising candidates for an infection-specific radiopharmaceutical, however, at present many basic aspects need to be investigated to better understand the mechanisms of binding and accumulation of this class of radiophARMaceuticals to bacteria.
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CAIX-targeting radiotracers for hypoxia imaging in head and neck cancer models.
Fokko J. Huizing,Javad Garousi,Jasper Lok,Gerben M. Franssen,Bianca A.W. Hoeben,Fredrik Y. Frejd,Otto C. Boerman,Johan Bussink,Vladimir Tolmachev,Sandra Heskamp +9 more
TL;DR: It is shown that different CAIX-targeting radiotracers can discriminate a low CAix-expressing tumor from a high CAIX -expressing head and neck cancer xenografts model, and [111In]In-DTPA-girentuximab showed the most promising results.
Journal ArticleDOI
Preclinical imaging in bone tissue engineering.
Manuela Ventura,Otto C. Boerman,Chris L. de Korte,Mark Rijpkema,Arend Heerschap,Egbert Oosterwijk,John A. Jansen,X. Frank Walboomers +7 more
TL;DR: This review focuses on preclinical imaging tools, each with its respective strengths and weaknesses, used alone or in combination, which will dramatically contribute to improve the knowledge on bone healing regenerative processes.
Journal ArticleDOI
[18]F FDG PET/CT imaging to monitor the therapeutic effect of liposome-encapsulated prednisolone in experimental rheumatoid arthritis
Tessa van der Geest,Josbert M. Metselaar,Josbert M. Metselaar,Danny Gerrits,Peter L E M van Lent,Gert Storm,Peter Laverman,Otto C. Boerman +7 more
TL;DR: The data show that [(18)F]FDG PET/CT could be used to monitor the progression of AIA and confirmed rapid and profound anti-inflammatory effects of PLP-containing PEG-liposomes that were also observed macroscopically and microscopically.