P. W. Teague

TL;DR: It is demonstrated that the distribution of genomic sequences between chromosomes has implications for nuclear structure and the findings are discussed in relation to a model of the human nucleus that is functionally compartmentalized.

TL;DR: It is argued that an even greater density of informative markers is required to test rigorously for association in this genomic region, because it could not detect linkage disequilibrium between all these markers in the control population.

TL;DR: Three consanguineous BBS families are homozygous for three adjacent chromosome 15 markers, consistent with identity by descent for this region, and a fourth group of families, estimated at 8%, are unlinked to all three of the above loci, showing that at least one other BBS locus remains to be found.

TL;DR: This single nucleotide polymorphism in the 3′ untranslated region of the hSert gene should provide a useful genetic marker in the evaluation of hSERT as a candidate gene influencing susceptibility to mood disorders.

TL;DR: In this article, the authors examined factors that might influence the occurrence of constitutional translocations in the population and identified chromosome size as the major determinant of translocation frequency, which probably reflects the large target size for double-strand breakage and repair presented by the largest chromosomes.