P
Pan Zhao
Researcher at Southern University of Science and Technology
Publications - 22
Citations - 403
Pan Zhao is an academic researcher from Southern University of Science and Technology. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 8, co-authored 16 publications receiving 190 citations. Previous affiliations of Pan Zhao include Jinan University.
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Journal ArticleDOI
Hypoxia-induced acetylation of PAK1 enhances autophagy and promotes brain tumorigenesis via phosphorylating ATG5
Xing Feng,Xing Feng,Heng Zhang,Lingbing Meng,Huiwen Song,Qingxin Zhou,Qingxin Zhou,Chao Qu,Pan Zhao,Pan Zhao,Qinghua Li,Chang Zou,Chang Zou,Xing Liu,Zhiyong Zhang,Zhiyong Zhang +15 more
TL;DR: It is reported that PAK1 (p21 [RAC1] activated kinase 1) is significantly upregulated and promotes GBM development and its regulator in the autophagy pathway might represent potential therapeutic targets for GBM treatment.
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γδ T cells in cancer immunotherapy.
TL;DR: Future direction for immunotherapy using γδ T cells should focus on overcoming the side effects of γ Δ T cells and exploring better antigens that help stimulating γ δ T cell expansion in vitro.
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Epitranscriptomics and epiproteomics in cancer drug resistance: therapeutic implications.
Huibin Song,Dongcheng Liu,Shaowei Dong,Leli Zeng,Leli Zeng,Zhuo-Xun Wu,Pan Zhao,Litu Zhang,Zhe-Sheng Chen,Chang Zou +9 more
TL;DR: The recent progress in overcoming cancer drug resistance is summarized in three novel aspects: mRNA modification, which includes alternative splicing, A-to-I modification and mRNA methylation, and posttranslational modification on molecules, which encompasses drug inactivation/efflux, drug target modifications, DNA damage repair, cell death resistance, EMT, and metastasis.
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Identification of a distinct luminal subgroup diagnosing and stratifying early stage prostate cancer by tissue-based single-cell RNA sequencing.
Xiaoshi Ma,Jinan Guo,Kaisheng Liu,Chen Lipeng,Dale Liu,Shaowei Dong,Jinquan Xia,Qiaoyun Long,Yongjian Yue,Pan Zhao,Fengyan Hu,Zhangang Xiao,Xinghua Pan,Kefeng Xiao,Zhiqiang Cheng,Zunfu Ke,Zhe-Sheng Chen,Chang Zou,Chang Zou +18 more
TL;DR: The findings provide a valuable resource for interpreting tumor heterogeneity in prostate cancer, and a novel candidate marker for prostate cancer management.
Journal ArticleDOI
Down-regulation of lncRNA Linc00152 suppressed cell viability, invasion, migration, and epithelial to mesenchymal transition, and reversed chemo-resistance in breast cancer cells.
TL;DR: The results suggested the oncogenic role of Linc00152 in the breast cancer progression and suggested it may provide a novel therapeutic target for the treatment of breast cancer.