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Paolo Pelosi

Researcher at University of Genoa

Publications -  975
Citations -  47463

Paolo Pelosi is an academic researcher from University of Genoa. The author has contributed to research in topics: Mechanical ventilation & Lung injury. The author has an hindex of 93, co-authored 852 publications receiving 37918 citations. Previous affiliations of Paolo Pelosi include University of Insubria & Heidelberg University.

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Brain–heart interaction after acute ischemic stroke

TL;DR: This review aims to highlight the pathophysiological mechanisms implicated in the interaction between the brain and the heart and their clinical consequences in AIS patients, as well as to provide specific recommendations for cardiovascular management after AIS.
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Lung parenchyma remodeling in acute respiratory distress syndrome.

TL;DR: Recent advances in the field of fibroproliferative ARDS/ALI are explored, with special emphasis on the physiological properties of the extracellular matrix, the mechanisms of remodeling, the impact of mechanical ventilation on lung fibrotic response, and therapeutic interventions in the remodeling process.
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Assessment of cardiac preload and left ventricular function under increasing levels of positive end-expiratory pressure

TL;DR: In the present study, ventilation with increasing levels of PEEP did not alter RV function, while LV function was impaired at the highest level of PEP, and unlike cardiac filling pressures, ITBV and RVEDV both provide valid estimates of cardiac preload even at high intrathoracic pressures.
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Pulmonary and extrapulmonary acute respiratory distress syndrome: myth or reality?

TL;DR: Heterogeneous acute respiratory distress syndrome patients are still considered to suffer from one syndrome, and are treated in the same way, although the range of different pathways that lead to pulmonary dysfunction makes it possible to better target clinical treatment.
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Ventilation in patients with intra-abdominal hypertension: what every critical care physician needs to know

TL;DR: This review will focus on how to deal with the respiratory derangements in critically ill patients with IAH and the optimal PEEP levels in these patients is still unknown.