P
Paolo Pelosi
Researcher at University of Genoa
Publications - 975
Citations - 47463
Paolo Pelosi is an academic researcher from University of Genoa. The author has contributed to research in topics: Mechanical ventilation & Lung injury. The author has an hindex of 93, co-authored 852 publications receiving 37918 citations. Previous affiliations of Paolo Pelosi include University of Insubria & Heidelberg University.
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Journal ArticleDOI
Effects of peep on lung injury, pulmonary function, systemic circulation and mortality in animals with uninjured lungs-a systematic review.
Anna Geke Algera,Luigi Pisani,Renato Carneiro de Freitas Chaves,Thiago Chaves Amorim,Thomas G. V. Cherpanath,Rogier M. Determann,Dave A. Dongelmans,Frederique Paulus,Pieter R. Tuinman,Paolo Pelosi,Marcelo Gama de Abreu,Marcus J. Schultz,Marcus J. Schultz,Ary Serpa Neto +13 more
TL;DR: It is uncertain whether PEEP, at any level, truly prevents lung injury, while most trials suggest potential harmful effects on the systemic circulation.
Journal ArticleDOI
Mortality after surgery in Europe – Authors' reply
Rupert M Pearse,Rui Moreno,Peter Bauer,Paolo Pelosi,Philipp G. H. Metnitz,Claudia Spies,Benoit Vallet,Jean Louis Vincent,Andreas Hoeft,Andrew Rhodes +9 more
TL;DR: Examination of Pearse and colleagues' data seems to refute their hypothesis—for example, Sweden has both a low mortality rate (1·8%) and a low rate of admission to critical care (3·2%).
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Effects of pentoxifylline on intestinal bacterial overgrowth, bacterial translocation and spontaneous bacterial peritonitis in cirrhotic rats with ascites.
Francesco Corradi,Claudia Brusasco,Javier Fernández,Jordi Vila,María José Ramírez,Tiago Sevá-Pereira,Guillermo Fernández-Varo,Ismail Ben Mosbah,Juan Acevedo,Anibal Silva,Patricia R. M. Rocco,Paolo Pelosi,Pere Ginès,Miquel Navasa +13 more
TL;DR: In cirrhotic rats with ascites, pentoxifylline as well as norfloxacin reduced intestinal bacterial overgrowth and bacterial translocation and prevented spontaneous bacterial peritonitis; (b) pentoxifyinglline, but not norfl oxacin, reduced oxidative stress in cecal mucosal.
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Effects of different tidal volumes in pulmonary and extrapulmonary lung injury with or without intraabdominal hypertension.
Cintia L. Santos,Lillian Moraes,Raquel S. Santos,Mariana G. Oliveira,Johnatas D. Silva,Tatiana Maron-Gutierrez,Debora S. Ornellas,Marcelo M. Morales,Vera Luiza Capelozzi,Nelson Jamel,Paolo Pelosi,Patricia R. M. Rocco,Cristiane S. N. B. Garcia +12 more
TL;DR: Intraabdominal hypertension increased inflammation and fibrogenesis in the lung independent of ALI etiology, and in extrapulmonary ALI associated with intraabdominals hypertension, higher tidal volume improved lung morphometry with lower inflammation in lung tissue.
Journal ArticleDOI
The Association of Intraoperative driving pressure with postoperative pulmonary complications in open versus closed abdominal surgery patients – a posthoc propensity score–weighted cohort analysis of the LAS VEGAS study
Guido Mazzinari,Ary Serpa Neto,Sabrine N.T. Hemmes,Göran Hedenstierna,Samir Jaber,Michael Hiesmayr,Markus W. Hollmann,Gary H. Mills,Marcos F. Vidal Melo,Rupert M Pearse,Christian Putensen,Werner Schmid,Paolo Severgnini,Hermann Wrigge,Oscar Diaz Cambronero,Lorenzo Ball,Marcelo Gama de Abreu,Paolo Pelosi,Marcus J. Schultz,Marcus J. Schultz +19 more
TL;DR: In this paper, the association of intraoperative driving pressure (ΔP) with postoperative pulmonary complications (PPCs) depends on the surgical approach during abdominal surgery and intraoperative adverse events.