P
Paolo Pelosi
Researcher at University of Genoa
Publications - 975
Citations - 47463
Paolo Pelosi is an academic researcher from University of Genoa. The author has contributed to research in topics: Mechanical ventilation & Lung injury. The author has an hindex of 93, co-authored 852 publications receiving 37918 citations. Previous affiliations of Paolo Pelosi include University of Insubria & Heidelberg University.
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Journal ArticleDOI
Stress ulcer prophylaxis with a proton pump inhibitor versus placebo in critically ill patients (SUP-ICU trial): study protocol for a randomised controlled trial
Mette Krag,Anders Perner,Jørn Wetterslev,Matt P. Wise,Mark Borthwick,Stepani Bendel,Paolo Pelosi,Frederik Keus,Anne Berit Guttormsen,Joerg C. Schefold,Morten Hylander Møller +10 more
TL;DR: The SUP-ICU trial will provide high-quality data on the benefits and harms of stress ulcer prophylaxis with a proton pump inhibitor in critically ill adult patients admitted in the ICU.
Journal ArticleDOI
The fragility of statistically significant findings in randomised controlled anaesthesiology trials: systematic review of the medical literature
Guido Mazzinari,Lorenzo Ball,A. Serpa Neto,Carlos L. Errando,Arjen M. Dondorp,Lieuwe D. J. Bos,M. Gama de Abreu,Paolo Pelosi,Marcus J. Schultz +8 more
TL;DR: The results of this systematic review suggest that statistically significant differences in randomised controlled anaesthesiology trials are regularly fragile, implying that the primary outcome status of patients lost to follow‐up could possibly have changed the reported effect.
Journal ArticleDOI
Elective Tracheostomy During Mechanical Ventilation in Patients Affected by COVID-19: Preliminary Case Series From Lombardy, Italy.
Mario Turri-Zanoni,Paolo Battaglia,Camilla Czaczkes,Paolo Pelosi,Paolo Castelnuovo,Luca Cabrini,Luca Cabrini +6 more
TL;DR: The preliminary experience supports the safety of tracheostomy, provided that appropriate protocols are strictly followed, and, prudentially, the postoperative care is still debated, and the protocol includes tracheal tube change not before 2 weeks after trachostomy.
Journal ArticleDOI
Systematic review and consensus definitions for the Standardised Endpoints in Perioperative Medicine initiative : clinical indicators
Guy Haller,Guy Haller,Sohail Bampoe,Tim Cook,Lee A. Fleisher,Michael P.W. Grocott,Mark I. Neuman,David A Story,Paul S. Myles,P. Myles,M. Grocott,B M Biccard,Jane M Blazeby,O. Boney,Matthew T. V. Chan,E. Diouf,Lee A. Fleisher,Cornelis J. Kalkman,A. Kurz,Ramani Moonesinghe,Duminda N. Wijeysundera,Tong J. Gan,Philip J Peyton,D. I. Sessler,Martin R. Tramèr,A. Cyna,G. S. De Oliveira,C. Wu,M.-B. Jensen,Henrik Kehlet,Mari Botti,G. Haller,T. Cook,Mark D. Neuman,D. Story,Russell L. Gruen,Sam Bampoe,Lisbeth Evered,David Scott,Brendan S. Silbert,D. van Dijk,Hilary P. Grocott,R. Eckenhoff,Lars S. Rasmussen,Lars Eriksson,Scott Beattie,Giovanni Landoni,Kate Leslie,Simon J. Howell,Peter Nagele,Toby Richards,Andre Lamy,Manoj M. Lalu,Rupert M Pearse,Monty G. Mythen,Jaume Canet,Ann Merete Møller,Tony Gin,M. Schultz,Paolo Pelosi,M. Gabreu,Emmanuel Futier,Ben Creagh-Brown,Tom E.F. Abbott,Andy Klein,Tomas Corcoran,D. Jamie Cooper,S. Dieleman,David R. McIlroy,Rinaldo Bellomo,Andrew D. Shaw,John R. Prowle,Keyvan Karkouti,J. Billings,David Mazer,M. Jayarajah,Michael P. Murphy,Justyna Bartoszko,R. Sneyd,Stephen Morris,Ronald B. George,Mark A Shulman,Meghan B. Lane-Fall,Ulrica Nilsson,N. Stevenson,Jamie Cooper,W. A. van Klei,Luca Cabrini,Timothy E. Miller,Nathan L. Pace,S. Jackson,Donal J. Buggy,Timothy G. Short,Bernhard Riedel,Vijaya Gottumukkala,Bilal Alkhaffaf,Mark D. Johnson +96 more
TL;DR: These clinical indicators can be confidently used as endpoints in clinical trials measuring quality, safety, and improvement in perioperative care.
Journal ArticleDOI
Impact of pressure profile and duration of recruitment maneuvers on morphofunctional and biochemical variables in experimental lung injury.
Pedro L. Silva,Lillian Moraes,Raquel S. Santos,Cynthia S. Samary,Debora S. Ornellas,Tatiana Maron-Gutierrez,Marcelo M. Morales,Felipe Saddy,Vera Luiza Capelozzi,Paolo Pelosi,John J. Marini,Marcelo Gama de Abreu,Patricia R. M. Rocco +12 more
TL;DR: Longer-duration RMs with slower airway pressure increase efficiently improved lung function, while minimizing the biological impact on lungs.