Patrick W. Goodwill

TL;DR: This paper derives the 1-D MPI signal, resolution, bandwidth requirements, signal-to-noise ratio (SNR), specific absorption rate, and slew rate limitations, and concludes with experimental data measuring the point spread function for commercially available SPIO nanoparticles.

TL;DR: In vivo results are presented showing that an emerging imaging modality, magnetic particle imaging (MPI), can be combined with magnetic hyperthermia into an image-guided theranostic platform, and quantitative MPI image guidance for treatment planning and use of the MPI gradients for spatial localization of magnetichyperthermia to arbitrarily selected regions.

TL;DR: X-space MPI provides a powerful framework for optimizing the size and magnetic properties of the iron oxide nanoparticle tracers used in MPI, which predicts that larger nanoparticles could enable up to 250 micrometer resolution imaging, which would represent a major breakthrough in safe imaging for CKD patients.

TL;DR: It is demonstrated both theoretically and experimentally that multidimensional MPI is a linear shift-invariant imaging system with an analytic point spread function and a fast image reconstruction method that obtains the intrinsic MPI image with high signal-to-noise ratio via a simple gridding operation in x-space.

TL;DR: Magnetic Particle Imaging shows great potential for an exciting array of applications, including stem cell tracking in vivo, first-pass contrast studies to diagnose or stage cancer, and inflammation imaging in vivo.