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Paul L. den Exter
Researcher at Leiden University Medical Center
Publications - 49
Citations - 1866
Paul L. den Exter is an academic researcher from Leiden University Medical Center. The author has contributed to research in topics: Pulmonary embolism & Medicine. The author has an hindex of 14, co-authored 39 publications receiving 1465 citations. Previous affiliations of Paul L. den Exter include Leiden University.
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Journal ArticleDOI
Age-Adjusted D-Dimer Cutoff Levels to Rule Out Pulmonary Embolism: The ADJUST-PE Study
Marc Philip Righini,Josien van Es,Paul L. den Exter,Pierre-Marie Roy,Franck Verschuren,Alexandre Ghuysen,Olivier Thierry Rutschmann,Olivier Sanchez,Morgan Jaffrelot,A Trinh-Duc,Catherine Le Gall,Farès Moustafa,Alessandra Principe,Anja A. van Houten,Marije Ten Wolde,Renée A. Douma,Germa Hazelaar,Petra M. G. Erkens,Klaas W Van Kralingen,Marco J. J. H. Grootenboers,Marc Durian,Y. Whitney Cheung,Guy Meyer,Henri Bounameaux,Menno V. Huisman,Pieter Willem Kamphuisen,Grégoire Le Gal +26 more
TL;DR: The combination of pretest clinical probability assessment with age-adjusted D-dimer cutoff was associated with a larger number of patients in whom PE could be considered ruled out with a low likelihood of subsequent clinical venous thromboembolism.
Journal ArticleDOI
Risk of Recurrent Venous Thromboembolism and Mortality in Patients With Cancer Incidentally Diagnosed With Pulmonary Embolism: A Comparison With Symptomatic Patients
TL;DR: It is suggested that oncology patients diagnosed with and treated for incidental PE, have similar high rates of recurrent venous thromboembolism, bleeding complications, and mortality, as compared with oncologists patients who develop symptomatic PE.
Journal ArticleDOI
Risk profile and clinical outcome of symptomatic subsegmental acute pulmonary embolism
Paul L. den Exter,Josien van Es,Frederikus A. Klok,Lucia J.M. Kroft,Marieke J. H. A. Kruip,Pieter Willem Kamphuisen,Harry R. Büller,Menno V. Huisman +7 more
TL;DR: It is indicated that patients with SSPE mimic those with more proximally located PE in regards to their risk profile and clinical outcome.
Journal ArticleDOI
Wells Rule and D-Dimer Testing to Rule Out Pulmonary Embolism A Systematic Review and Individual-Patient Data Meta-analysis
Nick van Es,Tom van der Hulle,Josien van Es,Paul L. den Exter,Renée A. Douma,Robbert J. Goekoop,Inge C. M. Mos,Javier Galipienzo,Pieter W. Kamphuisen,Menno V. Huisman,Frederikus A. Klok,Harry R. Büller,Patrick M.M. Bossuyt +12 more
TL;DR: A systematic review and IPD meta-analysis combining patient-level data from 6 large, prospective outcome studies in which diagnostic management of clinically suspected PE had been guided by the Wells rule and d-dimer testing is done.
Journal Article
Wells Rule and D-Dimer Testing to Rule Out Pulmonary Embolism
Nick van Es,Tom van der Hulle,Josien van Es,Paul L. den Exter,Renée A. Douma,Robbert J. Goekoop,Inge C. M. Mos,Javier Galipienzo,Pieter W. Kamphuisen,Menno V. Huisman,Frederikus A. Klok,Harry R. Büller,Patrick M.M. Bossuyt +12 more
TL;DR: In this article, a review of the use of the Wells rule with D-dimer testing to make decisions about imaging in patients with suspected pulmonary embolism is presented. But this review is limited to the case of lung cancer.