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Paula Hoff
Researcher at Humboldt University of Berlin
Publications - 69
Citations - 1745
Paula Hoff is an academic researcher from Humboldt University of Berlin. The author has contributed to research in topics: Bone healing & Medicine. The author has an hindex of 18, co-authored 58 publications receiving 1220 citations. Previous affiliations of Paula Hoff include Leibniz Association & Charité.
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Journal ArticleDOI
Immunogenicity and safety of anti-SARS-CoV-2 mRNA vaccines in patients with chronic inflammatory conditions and immunosuppressive therapy in a monocentric cohort.
Ulf Geisen,Dennis K Berner,Florian Tran,Melike Sümbül,Lena Vullriede,Maria Ciripoi,Hayley M Reid,Annika Schaffarzyk,Ann C Longardt,Jeanette Franzenburg,Paula Hoff,Jan H. Schirmer,R Zeuner,Anette Friedrichs,Andrea Steinbach,Christine Knies,Robert Markewitz,Peter J Morrison,Sascha Gerdes,Stefan Schreiber,Bimba F. Hoyer +20 more
TL;DR: In this paper, the efficacy and safety of anti-SARS-CoV-2 mRNA vaccines in a cohort of immunosuppressed patients as compared with healthy controls were presented for the first time.
Journal ArticleDOI
Inflammatory phase of bone healing initiates the regenerative healing cascade
Katharina Schmidt-Bleek,Hanna Schell,Norma Schulz,Paula Hoff,Carsten Perka,Frank Buttgereit,Hans-Dieter Volk,Jasmin Lienau,Georg N. Duda +8 more
TL;DR: This study suggests that there are unfavorable immune cells and factors participating in the initial healing phase and identifying beneficial aspects may lead to promising therapeutical approaches that might benefit further by eliminating the unfavorable factors.
Journal ArticleDOI
Hypoxia Promotes Osteogenesis but Suppresses Adipogenesis of Human Mesenchymal Stromal Cells in a Hypoxia-Inducible Factor-1 Dependent Manner
Markus Wagegg,Timo Gaber,Ferenz Leonard Lohanatha,M. Hahne,C. Strehl,Monique Fangradt,Cam Loan Tran,K Schönbeck,Paula Hoff,Andrea Ode,Carsten Perka,Georg N. Duda,Frank Buttgereit +12 more
TL;DR: It is concluded that the effects of hypoxia are crucial for effective bone healing, which may potentially lead to the development of novel therapeutic approaches.
Journal ArticleDOI
Initial immune reaction and angiogenesis in bone healing
Katharina Schmidt-Bleek,Hanna Schell,Jasmin Lienau,Norma Schulz,Paula Hoff,Michael Pfaff,Gregor Schmidt,Claudia Martin,Carsten Perka,Frank Buttgereit,Hans-Dieter Volk,Georg N. Duda +11 more
TL;DR: Prolonged pro‐inflammatory signaling occurring in a delayed bone‐healing model supports the finding that timely termination of inflammation furthers the regenerative process.
Journal ArticleDOI
Osteoarthritis synovial fluid activates pro-inflammatory cytokines in primary human chondrocytes
Paula Hoff,Frank Buttgereit,Gerd-Rüdiger Burmester,M. Jakstadt,Timo Gaber,Kristin Andreas,Georg Matziolis,Carsten Perka,Eric Röhner +8 more
TL;DR: Activation of pro- inflammatory cytokines of human chondrocytes by synovial fluids of OA patient supports a pro-inflammatory process in the pathogenesis of O a.