J
Jeanette Franzenburg
Researcher at University of Kiel
Publications - 6
Citations - 508
Jeanette Franzenburg is an academic researcher from University of Kiel. The author has contributed to research in topics: Internal medicine & Medicine. The author has an hindex of 2, co-authored 3 publications receiving 177 citations.
Papers
More filters
Journal ArticleDOI
Immunogenicity and safety of anti-SARS-CoV-2 mRNA vaccines in patients with chronic inflammatory conditions and immunosuppressive therapy in a monocentric cohort.
Ulf Geisen,Dennis K Berner,Florian Tran,Melike Sümbül,Lena Vullriede,Maria Ciripoi,Hayley M Reid,Annika Schaffarzyk,Ann C Longardt,Jeanette Franzenburg,Paula Hoff,Jan H. Schirmer,R Zeuner,Anette Friedrichs,Andrea Steinbach,Christine Knies,Robert Markewitz,Peter J Morrison,Sascha Gerdes,Stefan Schreiber,Bimba F. Hoyer +20 more
TL;DR: In this paper, the efficacy and safety of anti-SARS-CoV-2 mRNA vaccines in a cohort of immunosuppressed patients as compared with healthy controls were presented for the first time.
Journal ArticleDOI
Longitudinal Multi-omics Analyses Identify Responses of Megakaryocytes, Erythroid Cells, and Plasmablasts as Hallmarks of Severe COVID-19.
Joana P. Bernardes,Neha Mishra,Florian Tran,Thomas Bahmer,Lena Best,Johanna I. Blase,Dora Bordoni,Jeanette Franzenburg,Ulf Geisen,Jonathan Josephs-Spaulding,Philipp Köhler,Axel Künstner,Elisa Rosati,Anna C. Aschenbrenner,Petra Bacher,Nathan Baran,Teide Boysen,Burkhard Brandt,Niklas Bruse,Jonathan Dörr,Andreas Dräger,Gunnar Elke,David Ellinghaus,Julia Fischer,Michael Forster,Andre Franke,Sören Franzenburg,Norbert Frey,Anette Friedrichs,Janina Fuß,Andreas Glück,Jacob Hamm,Finn Hinrichsen,Marc P. Hoeppner,Simon Imm,Ralf Junker,Sina Kaiser,Ying H. Kan,Rainer Knoll,Christoph Lange,Georg Laue,Clemens Lier,Matthias Lindner,Georgios Marinos,Robert Markewitz,Jacob Nattermann,Rainer Noth,Peter Pickkers,Klaus F. Rabe,Alina Renz,Christoph Röcken,Jan Rupp,Annika Schaffarzyk,Alexander Scheffold,Jonas Schulte-Schrepping,Jonas Schulte-Schrepping,Domagoj Schunk,Dirk Skowasch,Thomas Ulas,Thomas Ulas,Klaus-Peter Wandinger,Michael Wittig,Johannes Zimmermann,Hauke Busch,Bimba F. Hoyer,Christoph Kaleta,Jan Heyckendorf,Matthijs Kox,Jan Rybniker,Stefan Schreiber,Joachim L. Schultze,Joachim L. Schultze,Philip Rosenstiel,Nicholas E. Banovich,Tushar J. Desai,Oliver Eickelberg,Muzlifa Haniffa,Peter Horvath,Jonathan A. Kropski,Robert Lafyatis,Joakim Lundeberg,Kerstin B. Meyer,Martijn C. Nawijn,Marko Nikolic,Jose Ordovas Montanes,Dana Pe'er,Purushothama Rao Tata,Emma L. Rawlins,Aviv Regev,Paul A. Reyfman,Christos Samakovlis,Joachim Schultze,Alex K. Shalek,Douglas P. Shepherd,Jason R. Spence,Sarah A. Teichmann,Fabian J. Theis,Alexander M. Tsankov,Maarten van den Berge,Michael von Papen,Jeffrey A. Whitsett,Laure-Emmanuelle Zaragosi,Angel Angelov,Robert Bals,Alexander Bartholomäus,Anke Becker,Daniela Bezdan,Ezio Bonifacio,Peer Bork,Thomas Clavel,Maria Colme-Tatche,Andreas Diefenbach,Alexander T. Dilthey,Nicole Fischer,Konrad U. Förstner,Julia-Stefanie Frick,Julien Gagneur,Alexander Goesmann,Torsten Hain,Michael Hummel,Stefan Janssen,Jörn Kalinowski,René Kallies,Birte Kehr,Andreas Keller,Sarah Kim-Hellmuth,Christoph Klein,Oliver Kohlbacher,Jan O. Korbel,Ingo Kurth,Markus Landthaler,Yang Li,Kerstin U. Ludwig,Oliwia Makarewicz,Manja Marz,Alice C. McHardy,Christian Mertes,Markus M. Nöthen,Peter Nürnberg,Uwe Ohler,Stephan Ossowski,Jörg Overmann,Silke Peter,Klaus Pfeffer,Anna R. Poetsch,Alfred Pühler,Niklaus Rajewsky,Markus Ralser,Olaf Rieß,Stephan Ripke,Ulisses Nunes da Rocha,Antoine-Emmanuel Saliba,Leif E. Sander,Birgit Sawitzki,Philipp H. Schiffer,Eva-Christina Schulte,Alexander Sczyrba,Oliver Stegle,Jens Stoye,Janne Vehreschild,Jörg Vogel,Max von Kleist,Andreas Walker,Jörn Walter,Dagmar Wieczorek,John Ziebuhr +165 more
TL;DR: The study demonstrates broad cellular effects of SARS-CoV-2 infection beyond classical immune cells and may serve as an entry point to develop biomarkers and targeted treatments of patients with COVID-19.
Journal ArticleDOI
Analysis of the Seasonal Fluctuation of γδ T Cells and Its Potential Relation with Vitamin D3
Birthe Bernicke,Nils Engelbogen,Katharina Klein,Jeanette Franzenburg,Christoph Borzikowsky,Christian J. Peters,Ottmar Janssen,Ralf Junker,Rubén Hernández Serrano,Dieter Kabelitz +9 more
TL;DR: Novel insights are revealed into the seasonal fluctuation of γδ T cells and the immunomodulatory effects of vitamin D3 and the active metabolite 1α,25(OH)2D3 inhibited the in vitro activation ofγε T cells at the level of proliferation, cytotoxicity, and interferon-γ production.
Posted ContentDOI
Longitudinal multi-omics analysis identifies responses of megakaryocytes, erythroid cells and plasmablasts as hallmarks of severe COVID-19 trajectories
Joana P. Bernardes,Neha Mishra,Florian Tran,Thomas Bahmer,Lena Best,Johanna I. Blase,Dora Bordoni,Jeanette Franzenburg,Ulf Geisen,Jonathan Josephs-Spaulding,Philipp Koehler,Axel Kuenstner,Elisa Rosati,Anna C. Aschenbrenner,Petra Bacher,Nathan Baran,Teide Boysen,Burkhard Brandt,Niklas Bruse,Jonathan Doerr,Andreas Draeger,Gunnar Elke,David Ellinghaus,Julia Fischer,Michael Forster,Andre Franke,Soeren Franzenburg,Norbert Frey,Anette Friedrichs,Janina Fuss,Andreas Glueck,Jacob Hamm,Finn Hinrichsen,Marc P. Hoeppner,Simon Imm,Ralf Juenker,Sina Kaiser,Ying H. Kan,Rainer Knoll,Christoph Lange,Georg Laue,Clemes Lier,Matthias Lindner,Georgios Marinos,Robert Markewitz,Jacob Nattermann,Rainer Noth,Peter Pickkers,Klaus F. Rabe,Alina Renz,Christoph Roecken,Jan Rupp,Annika Schaffarzyk,Alexander Scheffold,Jonas Schulte-Schrepping,Domagoj Schunck,Dirk Skowasch,Thomas Ulas,Klaus-Peter Wandinger,Michael Wittig,Johannes Zimmermann,Hauke Busch,Bimba F. Hoyer,Christoph Kaleta,Jan Heyckendorf,Matthijs Kox,Jan Rybniker,Stefan Schreiber,Joachim L. Schultze,Joachim L. Schultze,Philip Rosenstiel,Deutsche Covid Omics Initiative +71 more
TL;DR: A longitudinal multi-omics study demonstrates distinct cellular and gene expression dynamics upon SARS-CoV-2 infection, which point to metabolic shifts of circulating immune cells, and reveals changes in megakaryocytes and increased erythropoiesis as important outcome indicators in severe COVID-19 patients.
Journal ArticleDOI
Increased protease-activated receptor 1 autoantibodies are associated with severe COVID-19
Florian Tran,Danielle M Harris,A. Scharmacher,Hanna Grasshoff,Kristina Sterner,Susanne Schinke,Nadja Käding,Jens Y Humrich,Otavio Cabral-Marques,Joana P. Bernardes,Neha Mishra,Thomas Bahmer,Jeanette Franzenburg,Bimba F. Hoyer,Andreas Glück,Martina Guggeis,Alexander Ossysek,Andre Küller,Derk Frank,Christoph Lange,Jan Rupp,Jan Heyckendorf,Karoline I. Gaede,Howard Amital,Philip Rosenstiel,Yehuda Shoenfeld,Gilad Halpert,Avi Z. Rosenberg,K Schulze-Forster,Harald Heidecke,Gabriela Riemekasten,Stefan Schreiber +31 more
TL;DR: A systematic screening for abs confirmed induction of diverse functional abs in SARS-CoV-2 infection, targeting several immunomodulatory proteins, including cytokines/chemokines and their respective G-protein coupled receptors (GPCR).