Pegah Tootoonchi Afshar

TL;DR: A new method based on the combined analysis of short reads and long reads generated by second- and third-generation sequencing and a custom-designed method for isoform identification and quantification is developed to generate a high-confidence isoform dataset for human embryonic stem cells (hESCs).

TL;DR: An extensive study analysing a broad spectrum of RNA-seq workflows and proposing a comprehensive analysis protocol, named RNACocktail, along with a computational pipeline achieving high accuracy, which could help researchers extract more biologically relevant predictions by broad analysis of the transcriptome.

TL;DR: The results show that IDP-fusion will be useful for unraveling the complexity of multiple fusion splices and fusion isoforms within tumorigenesis-relevant fusion genes.

TL;DR: SomaticSeq is an accurate somatic mutation detection pipeline implementing a stochastic boosting algorithm to produce highly accurate somatics mutation calls for both single nucleotide variants and small insertions and deletions that achieves better overall accuracy than any individual tool incorporated.

TL;DR: In this paper, an energy conserving TDM-PON architecture using sleep mode ONU with fast wake-up capability is demonstrated. But this architecture employs novel just-in-time sleep control scheme to enhance energy conservation and buffering performances.