P
Pei-Ju Liao
Researcher at National University of Singapore
Publications - 9
Citations - 226
Pei-Ju Liao is an academic researcher from National University of Singapore. The author has contributed to research in topics: Cancer cell & Cancer. The author has an hindex of 6, co-authored 9 publications receiving 184 citations. Previous affiliations of Pei-Ju Liao include Chung Shan Medical University.
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Journal ArticleDOI
Identification of mutations in members of the connexin gene family as a cause of nonsyndromic deafness in Taiwan.
TL;DR: This study provides information for understanding the importance of genetic factors in nonsyndromic deafness of the Taiwanese and may be of use in the improvement of genetic diagnosis of hearing loss in Taiwan.
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Dual blockade of the lipid kinase PIP4Ks and mitotic pathways leads to cancer-selective lethality.
Mayumi Kitagawa,Pei-Ju Liao,Kyunghee Lee,Jasmine Wong,See Cheng Shang,Noriaki Minami,Oltea Sampetrean,Hideyuki Saya,Dai Lingyun,Nayana Prabhu,Go Ka Diam,Radoslaw M. Sobota,Andreas Larsson,Pär Nordlund,Pär Nordlund,Pär Nordlund,Frank McCormick,Sujoy Ghosh,Sujoy Ghosh,David M. Epstein,Brian W. Dymock,Sang Hyun Lee +21 more
TL;DR: A molecule a131 with dual-inhibitory properties is identified, which targets PI5P4K and mitosis, and it is involved in Ras/Raf/MEK/ERK and PI3K/Akt/mTOR crosstalk, thereby causing reversible growth arrest in normal cells and cell death of tumor cells.
Journal ArticleDOI
Opposing Activities of Aurora B Kinase and B56-PP2A Phosphatase on MKlp2 Determine Abscission Timing
TL;DR: Abscission is determined by the balance of Aurora B and B56-PP2A activities on MKlp2 S878 within the LAM, which establishes a key mechanism for Aurora B regulation of abscission in mammalian cells.
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Expression patterns of connexin 29 (GJE1) in mouse and rat cochlea
TL;DR: A comprehensive and detailed pattern of Cx29 gene expression in the mouse and rat cochlea is provided, which allows the identification of candidate genes for deafness and provides important insight into mechanisms that lead to deafness due to mutations in CX29 gene.
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The Tumor Suppressor Cdkn3 Is Required for Maintaining the Proper Number of Centrosomes by Regulating the Centrosomal Stability of Mps1
TL;DR: It is suggested that Mps1 and Cdkn3 form a self-regulated feedback loop at centrosomes to tightly control the centrosomal levels of MPS1, which prevents centrosome overduplication in human cells.