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Per E. Schwarze

Researcher at Norwegian Institute of Public Health

Publications -  162
Citations -  10861

Per E. Schwarze is an academic researcher from Norwegian Institute of Public Health. The author has contributed to research in topics: Environmental exposure & Apoptosis. The author has an hindex of 51, co-authored 158 publications receiving 9226 citations.

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Associations between environmental exposures and serum concentrations of Clara cell protein among elderly men in Oslo, Norway.

TL;DR: The present study explored associations between environmental exposures and serum concentrations of lung Clara cell protein 16kDa, a biomarker that has recently been used to assess the integrity of the lung epithelium, and suggested that acute environmental exposures may compromise the integrityof the lung tissue and lead to increased epithelial barrier permeability in the lungs of elderly men.
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Iron release and ROS generation from mineral particles are not related to cytokine release or apoptosis in exposed A549 cells.

TL;DR: Neither iron content nor the ability to induce ROS generation appears to be a prerequisite for the inflammatory potential or cytotoxicity of mineral particles.
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Differential NF-κB and MAPK activation underlies fluoride- and TPA-mediated CXCL8 (IL-8) induction in lung epithelial cells

TL;DR: A strong, rapid, and relatively transient activation of ERK1/2 in combination with NF-kB may be sufficient for a strong induction of CXCL8, which may exceed the effects of a more moderate ERK 1/2 activation in combinationWith activation of p38, JNK1/ 2, and NF-κB.