K
Kjersti S. Rønningen
Researcher at Norwegian Institute of Public Health
Publications - 96
Citations - 7506
Kjersti S. Rønningen is an academic researcher from Norwegian Institute of Public Health. The author has contributed to research in topics: Linkage disequilibrium & Population. The author has an hindex of 41, co-authored 95 publications receiving 7313 citations.
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Journal ArticleDOI
Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease
H Ueda,Howson Jmm.,Laura Esposito,Joanne M. Heward,Hywel Snook,Giselle Chamberlain,Dan Rainbow,Hunter Kmd.,Anne Smith,G Di Genova,G Di Genova,Mathias H. Herr,Mathias H. Herr,Ingrid Dahlman,Ingrid Dahlman,F Payne,Deborah J. Smyth,Christopher E. Lowe,Twells Rcj.,Sarah Howlett,Barry C. Healy,Sarah Nutland,Helen E. Rance,Vincent H. Everett,Luc J. Smink,A C Lam,Heather J. Cordell,Neil Walker,C Bordin,John S. Hulme,Costantino Motzo,Francesco Cucca,J F Hess,Michael L. Metzker,Michael L. Metzker,Jane Rogers,Simon G. Gregory,Amit Allahabadia,Amit Allahabadia,R Nithiyananthan,Eva Tuomilehto-Wolf,Jaakko Tuomilehto,Polly J. Bingley,Kathleen M Gillespie,Dag E. Undlien,Kjersti S. Rønningen,Cristian Guja,Constantin Ionescu-Tirgoviste,David A. Savage,Alexander P. Maxwell,Dennis Carson,Christopher Patterson,Jayne A. Franklyn,David Clayton,Laurence B. Peterson,Linda S. Wicker,John A. Todd,Gough Scl. +57 more
TL;DR: In this article, the authors identify polymorphisms of the cytotoxic T lymphocyte antigen 4 gene (CTLA4) as candidates for primary determinants of risk of the common autoimmune disorders Graves' disease, autoimmune hypothyroidism and type 1 diabetes.
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Remapping the insulin gene/IDDM2 locus in type 1 diabetes.
Bryan J. Barratt,Felicity Payne,Christopher E. Lowe,Robert Hermann,Barry C. Healy,Denise Harold,Patrick Concannon,Neda Gharani,Mark I. McCarthy,Mark Olavesen,Rose McCormack,Cristian Guja,Constantin Ionescu-Tirgoviste,Dag E. Undlien,Kjersti S. Rønningen,Kathleen M Gillespie,Eva Tuomilehto-Wolf,Jaakko Tuomilehto,Simon T. Bennett,David Clayton,Heather J. Cordell,John A. Todd +21 more
TL;DR: Mapping results using robust regression methods show how precisely a variant for a common disease can be mapped, even within a region of strong LD, and specifically that IDDM2 maps to one or more of three common variants in a approximately 2-kb region of chromosome 11p15.
Journal ArticleDOI
Linkage disequilibrium mapping of a type 1 diabetes susceptibility gene (IDDM7) to chromosome 2q31-q33.
J B Copeman,Francesco Cucca,C M Hearne,Richard J. Cornall,Peter W. Reed,Kjersti S. Rønningen,Dag E. Undlien,Lorenza Nisticò,Raffaella Buzzetti,Roberto Tosi +9 more
TL;DR: The utility of polymorphic microsatellites for linkage disequilibrium mapping of genes for complex diseases is demonstrated, with evidence localizes a new diabetes susceptibility gene, IDDM7, to within two centiMorgans of D2S152.
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The biobank of the Norwegian mother and child cohort Study: A resource for the next 100 years
Kjersti S. Rønningen,Liv Paltiel,Helle Margrete Meltzer,Rannveig Nordhagen,Kari Kveim Lie,Ragnhild Hovengen,Margaretha Haugen,Wenche Nystad,Per Magnus,Jane A. Hoppin +9 more
TL;DR: With the unique combination of biological specimens and questionnaire data, the MoBa Study will constitute a resource for many future investigations of the separate and combined effects of genetic, environmental factors on pregnancy outcome and on human morbidity, mortality and health in general.
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Particular HLA-DQ molecules play a dominant role in determining susceptibility or resistance to Type 1 (insulin-dependent) diabetes mellitus
TL;DR: Genes in the HLA complex are by far the most important in determining genetic predisposition or resistance to Type 1 (insulin-dependent) diabetes mellitus, and evidence is presented that theHLA genes mainly involved are those encoding some particular HLA-DQ molecules.