Peter Goodhand

TL;DR: This work reviews the diversity of approaches and current progress made by national genomic-medicine initiatives in the UK, France, Australia, and US and provides a roadmap for sharing strategies, standards, and data internationally to accelerate implementation.

TL;DR: This data-sharing effort has led to improved variant interpretation and development of treatments for rare diseases and some cancer types, but such benefits will only be available to the general population if researchers and clinicians can access and make comparisons across data from millions of individuals.

TL;DR: The BRCA Challenge has brought together the existing international Evidence-based Network for the Interpretation of Germline Mutant Alleles (ENIGMA) consortium expert panel, along with expert clinicians, diagnosticians, researchers, and database providers, all with a common goal of advancing the understanding of BRC a1 and BRCa2 variation.

TL;DR: The Beacon protocol is described and how it can be used as a model for the federated discovery and sharing of genomic data.

TL;DR: A crude model for estimating the rate of healthcare-funded genomes worldwide is presented that accounts for the preparedness of each country for genomics, and infers a progression of cancer-related sequencing over time.