P
Peter Lichtner
Researcher at Technische Universität München
Publications - 195
Citations - 33352
Peter Lichtner is an academic researcher from Technische Universität München. The author has contributed to research in topics: Population & Genome-wide association study. The author has an hindex of 70, co-authored 195 publications receiving 30077 citations. Previous affiliations of Peter Lichtner include Helmholtz Zentrum München & Dresden University of Technology.
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Journal ArticleDOI
Genetic determinants of the humoral immune response in MS.
Christiane Gasperi,Till F. M. Andlauer,Ana Keating,Benjamin Knier,Ana Klein,Verena Pernpeintner,Peter Lichtner,Ralf Gold,Frauke Zipp,Florian Then Bergh,Martin Stangel,Hayrettin Tumani,Brigitte Wildemann,Heinz Wiendl,Antonios Bayas,Tania Kümpfel,Uwe K. Zettl,Ralf A. Linker,Ulf Ziemann,M. Knop,Clemens Warnke,Manuel A. Friese,Friedemann Paul,Björn Tackenberg,Achim Berthele,Bernhard Hemmer +25 more
TL;DR: Although some HLA alleles seem to primarily drive the extent of humoral immune responses in the CNS by increasing CSF B cells and plasmablasts, genetic variants at the Immunoglobulin heavy chain constant locus might regulate intrathecal immunoglobulins levels via different mechanisms.
Journal Article
New loci for restless legs syndrome map to chromosome 4q and 17p
Juliane Winkelmann,Peter Lichtner,David Kemlink,Polo O,Pasquale Montagna,Birgit Högl,Karin Stiasny-Kolster,Georgios M. Hadjigeorgiou,Benno Pütz,Claudia Trenkwalder,Thomas Meitinger,Bertram Müller-Myhsok +11 more
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Blood cis-eQTL analysis fails to identify novel association signals among sub-threshold candidates from genome-wide association studies in restless legs syndrome.
Eva C. Schulte,Katharina Schramm,Claudia Schurmann,Peter Lichtner,Christian Herder,Michael Roden,Christian Gieger,Annette Peters,Claudia Trenkwalder,Birgit Högl,Birgit Frauscher,Klaus Berger,Ingo Fietze,Nadine Gross,Karin Stiasny-Kolster,Wolfgang H. Oertel,Cornelius G. Bachmann,Walter Paulus,Alexander Zimprich,Henry Völzke,Ulf Schminke,Matthias Nauck,Thomas Illig,Thomas Meitinger,Bertram Müller-Myhsok,Holger Prokisch,Juliane Winkelmann +26 more
TL;DR: Assessment of the 332 best-associated SNPs from the genome-wide phase of the to date largest RLS GWAS for cis-eQTL effects in peripheral blood from individuals of European descent was unable to identify new genetic susceptibility factor for RLS by adding this novel level of functional assessment to RLS data.
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Complete form of X-linked congenital stationary night blindness: refined mapping and evidence of genetic homogeneity.
Carsten M. Pusch,Johannes Maurer,Juliane Ramser,Jürgen Tomiuk,Helene Achatz,Katrin Pesch,Peter Lichtner,Eckart Apfelstedt-Sylla,Felix K. Jacobi,Wolfgang Berger,Alfons Meindl,Bernd Wissinger +11 more
TL;DR: Evidence of genetic homogeneity in the disorder is provided after subsequent mutation analyses in CSNB1 patients revealed no pathogenic sequence alterations in DFFRX and CASK genes, but retain candidates for other diseases mapping to that region.
Journal ArticleDOI
Epsilon-sarcoglycan is not involved in sporadic Gilles de la Tourette syndrome.
Friedrich Asmus,Sarah Schoenian,Peter Lichtner,Marita Munz,Petra Mayer,Bertram Müller-Myhsok,Alexander Zimprich,Helmut Remschmidt,Johannes Hebebrand,Oliver Bandmann,Thomas Gasser +10 more
TL;DR: Screening 83 sporadic childhood-onset GTS patients for an involvement of epsilon-sarcoglycan gene at chromosome 7q21.3 found variant peak patterns for exon 3 could be explained by a polymorphic CA repeat 38 bp F.