M
Martin Stangel
Researcher at Hannover Medical School
Publications - 337
Citations - 12014
Martin Stangel is an academic researcher from Hannover Medical School. The author has contributed to research in topics: Remyelination & Multiple sclerosis. The author has an hindex of 54, co-authored 324 publications receiving 9709 citations. Previous affiliations of Martin Stangel include Hochschule Hannover & Ruhr University Bochum.
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Journal ArticleDOI
Contrasting disease patterns in seropositive and seronegative neuromyelitis optica: A multicentre study of 175 patients
Sven Jarius,Klemens Ruprecht,Brigitte Wildemann,Tania Kuempfel,Marius Ringelstein,Christian Geis,Ingo Kleiter,Ingo Kleiter,Christoph Kleinschnitz,Achim Berthele,Johannes Brettschneider,Kerstin Hellwig,Bernhard Hemmer,Ralf A. Linker,Ralf A. Linker,Florian Lauda,Christoph Mayer,Hayrettin Tumani,Arthur Melms,Corinna Trebst,Martin Stangel,Martin Marziniak,Frank Hoffmann,Sven Schippling,Jürgen H. Faiss,Oliver Neuhaus,Barbara Ettrich,Christian Zentner,Kersten Guthke,Ulrich Hofstadt-van Oy,Reinhard Reuss,Hannah L. Pellkofer,Ulf Ziemann,Peter Kern,Klaus Peter Wandinger,Florian Then Bergh,Tobias Boettcher,Stefan Langel,Martin Liebetrau,Paulus S. Rommer,Sabine Niehaus,Christoph Münch,Alexander Winkelmann,Uwe K Zettl U,Imke Metz,Christian Veauthier,Jörn P Sieb,C. Wilke,Hans Hartung,Orhan Aktas,Friedemann Paul +50 more
TL;DR: This study provides an overview of the clinical and paraclinical features of NMOSD in Caucasians and demonstrates a number of distinct disease characteristics in seropositive and seronegative patients.
Journal ArticleDOI
Transferrin receptor internalization sequence YXRF implicates a tight turn as the structural recognition motif for endocytosis
James F. Collawn,Martin Stangel,Leslie A. Kuhn,Victor Esekogwu,Shuqian Jing,Ian S. Trowbridge,John A. Tainer +6 more
TL;DR: Two distinct internalization sequences favor a common structural chemistry and implicate an exposed tight turn as the recognition motif for high efficiency endocytosis.
Journal ArticleDOI
Safety and efficacy of eculizumab in anti-acetylcholine receptor antibody-positive refractory generalised myasthenia gravis (REGAIN): a phase 3, randomised, double-blind, placebo-controlled, multicentre study
James F. Howard,Kimiaki Utsugisawa,Michael Benatar,Hiroyuki Murai,Richard J. Barohn,Isabel Illa,Saiju Jacob,John Vissing,Ted M. Burns,John T. Kissel,Srikanth Muppidi,Richard Nowak,Fanny O'Brien,Jing Jing Wang,Renato Mantegazza,Claudio Mazia,Miguel Wilken,Carolina Ortea,Juliet Saba,Marcelo Rugiero,Mariela Bettini,Gonzalo Vidal,Alejandra Dalila Garcia,Phillipa Lamont,Wai-Kuen Leong,Heidi Boterhoven,Beverly Fyfe,Leslie Roberts,Mahi Jasinarachchi,Natasha Willlems,Julia Wanschitz,Wolfgang Löscher,Jan De Bleecker,Guy Van den Abeele,Kathy de Koning,Katrien De Mey,Rudy Mercelis,Linda Wagemaekers,Delphine Mahieu,Philip Van Damme,Charlotte Smetcoren,Olivier Stevens,Sarah Verjans,Ann D'Hondt,Petra Tilkin,Alzira Alves de Siqueira Carvalho,Rosa Hasan,Igor Dias Brockhausen,David Feder,Daniel Ambrosio,Ana Paula Melo,Rosana Rocha,Bruno Bezerra Rosa,Thabata Veiga,Luiz Augusto da Silva,Jordana Gonçalves Geraldo,Maria da Penha Morita Ananias,Erica Nogueira Coelho,Gabriel Paiva,Marina Pozo,Natalia Prando,Debora Dada Martineli Torres,Cristiani Fernanda Butinhao,Erica Coelho,Luciana Renata Cubas Volpe,Gustavo Duran,Tamires Cristina Gomes da Silva,Luiz Otavio Maia Gonçalves,Lucas Eduardo Pazetto,Luciana Souza Duca,Tomás Augusto Suriane Fialho,Maurício André Gheller Friedrich,Alexandre Guerreiro,Henrique Mohr,Maurer Pereira Martins,Daiane da Cruz Pacheco,Ana Paula Macagnan,Aline de Cassia Santos,Acary Souza Bulle Oliveira,Ana Carolina Amaral de Andrade,Marcelo Annes,Valeria Cavalcante Lino,Wladimir Bocca Vieira de Rezende Pinto,Carolina Miranda,Fernanda Carrara,Iandra Souza,Angela Genge,Rami Massie,Natasha Campbell,Vera Bril,Hans D. Katzberg,Mehran Soltani,Eduardo Ng,Zaeem A. Siddiqi,Celile Phan,Derrick Blackmore,Stanislav Vohanka,Josef Bednarik,Magda Chmelikova,Marek Čierny,Stanislava Toncrova,Jana Junkerova,Barbora Kurkova,Katarina Reguliova,Olga Zapletalova,Jiri Pitha,Iveta Novakova,Michaela Tyblova,Marcela Wolfova,Ivana Jurajdova,Henning Andersen,Thomas Harbo,Lotte Vinge,Anita Mogensen,Joan Højgaard,Nanna Witting,Anne Mette Ostergaard Autzen,Jane Pedersen,Markus Färkkilä,Sari Atula,Anne Nyrhinen,Juha-Pekka Erälinna,Mikko Laaksonen,Olli Oksaranta,Jaana Eriksson,Tuula Harrison,Claude Desnuelle,Sabrina Sacconi,Marie-Hélène Soriani,Sonia Decressac,Julie Moutarde,Pauline Lahaut,Guilhem Sole,Gwendal Le Masson,Anne-Cécile Wielanek-Bachelet,Morgane Gaboreau,Caroline Moreau,Amy Wilson,Christophe Vial,Francoise Bouhour,Helene Gervais-Bernard,Hélène Merle,Caroline Hourquin,Arnaud Lacour,Olivier Outteryck,Patrick Vermersch,Hélène Zéphir,Edouard Millois,Michel Deneve,Fabienne Deruelle,Benedikt Schoser,Stephan Wenninger,Martin Stangel,Sascha Alvermann,Stefan Gingele,Thomas Skripuletz,Kurt-Wolfram Suehs,C. Trebst,Karin Fricke,Sotirios Papagiannopoulos,Sevasti Bostantzopoulou,Nicholas Vlaikidis,Martha Zampaki,Nikoletta Papadopoulou,Dimos-Dimitrios Mitsikostas,Eleni Kasioti,Efstathia Mitropoulou,Despoina Charalambous,Csilla Rozsa,Melinda Horvath,Gabor Lovas,Judit Matolcsi,Gyorgyi Szabo,Brigitta Szabadosne,László Vécsei,Livia Dezsi,Edina Varga,Monika Konyane,Bella Gross,Olga Azrilin,Nelly Greenbereg,Hila Bali Kuperman,Giovanni Antonini,Matteo Garibaldi,Stefania Morino,Fernanda Troili,Antonella Di Pasquale,Alessandro Filla,Teresa Costabile,Enrico Marano,Francesco Saccà,Angela Marsil,Giorgia Puorro,Michelangelo Maestri Tassoni,Anna De Rosa,Silvia Bonanno,Carlo Antozzi,Lorenzo Maggi,Angela Campanella,Corrado Angelini,Paola Cudia,Valentina Pegoraro,Elena Pinzan,Francesca Bevilacqua,Daniele Orrico,Domenico Marco Bonifati,Amelia Evoli,Paolo Emilio Alboini,Valentina Damato,Raffaele Iorio,Maurizio Inghilleri,Laura Fionda,Vittorio Frasca,Elena Giacomelli,Maria Cristina Gori,Diego Lopergolo,Emanuela Onesti,Maria Gabriele,Francesco Patti,Andrea Caramma,Silvia Messina,Ester Reggio,Cinzia Caserta,Akiyuki Uzawa,Tetsuya Kanai,Masahiro Mori,Yoko Kaneko,Akiko Kanzaki,Eri Kobayashi,Katsuhisa Masaki,Dai Matsuse,Takuya Matsushita,Taira Uehara,Misa Shimpo,Maki Jingu,Keiko Kikutake,Yumiko Nakamura,Yoshiko Sano,Yuriko Nagane,Ikuko Kamegamori,Yuko Fujii,Kazumi Futono,Tomoko Tsuda,Yuka Saito,Hidekazu Suzuki,Miyuki Morikawa,Makoto Samukawa,Sachiko Kamakura,Hirokazu Shiraishi,Teiichiro Mitazaki,Masakatsu Motomura,Akihiro Mukaino,Shunsuke Yoshimura,Shizuka Asada,Tomomi Kobashikawa,Megumi Koga,Yasuko Maeda,Kazumi Takada,Mihoko Takada Takada,Yumi Yamashita,Seiko Yoshida,Yasushi Suzuki,Tetsuya Akiyama,Koichi Narikawa,Kenichi Tsukita,Fumie Meguro,Yusuke Fukuda,Miwako Sato,Hidenori Matsuo,Takayasu Fukudome,Yuichiro Gondo,Yasuhiro Maeda,Akiko Nagaishi,Shunya Nakane,Yoshinori Okubo,Meinoshin Okumura,Soichiro Funaka,Tomohiro Kawamura,Masayuki Makamori,Masanori Takahashi,Tomoya Hasuike,Eriko Higuchi,Hisako Kobayashi,Kaori Osakada,Namie Taichi,Emiko Tsuda,Takashi Hayashi,Shin Hisahara,Tomihiro Imai,Jun Kawamata,Takashi Murahara,Masaki Saitoh,Shun Shimohama,Shuichiro Suzuki,Daisuke Yamamoto,Shingo Konno,Tomomi Imamura,Masashi Inoue,Mayumi Murata,Hiroshi Nakazora,Ritsu Nakayama,Yasuko Ikeda,Miki Ogawa,Maoko Shirane,Takashi Kanda,M. Kawai,Michiaki Koga,Junichi Ogasawara,Masatoshi Omoto,Yasuteru Sano,Hideki Arima,Sachie Fukui,Shigemi Shimose,Hirokazu Shinozaki,Masanori Watanabe,Chieko Yoshikawa,Anneke J. van der Kooi,Marianne de Visser,Tamar Gibson,Jos Maessen,Marc H. De Baets,Catherine Faber,Maria Johanna Keijzers,Monique Miesen,Anna Kostera-Pruszczyk,Anna Kaminska,Byung Jo Kim,Chang Nyoung Lee,Yong Seo Koo,Hung Youl Seok,Hoo Nam Kang,HyeJin Ra,Byoung Joon Kim,Eun Bin Cho,HyeLim Lee,Ju-Hong Min,Jinmyoung Seok,Da Yoon Koh,JuYoung Kwon,Ji Eun Lee,SangAe Park,Yoon-Ho Hong,Jae-Sung Lim,Miri Kim,Seung Min Kim,Yool-hee Kim,Hyung Seok Lee,Ha Young Shin,Eun Bi Hwang,Miju Shin,Denis Sazonov,Asya Yarmoschuk,Larisa Babenko,Nadezhda Malkova,Anna Melnikova,Denis Korobko,Evgeniya Kosykh,Dmitry Pokhabov,Yulia Nesterova,Vladislav Abramov,Victor Balyazin,Carlos Casasnovas Pons,Maria Antonia Alberti Aguilo,Christian Homedes-Pedret,Natalia Julia Palacios,Ana Lazaro,Exuperio Diez Tejedor,Mireya Fernandez-Fournier,Pedro Lopez Ruiz,Francisco Javier Rodriguez de Rivera,Maria Salvado Figueras,Josep Gamez,Maria Salvado,Elena Cortes Vicente,Jordi Díaz-Manera,Luis Antonio Querol Gutierrez,Ricardo Rojas Garcia,Nuria Vidal,Elisabet Arribas-Ibar,Fredrik Piehl,Albert Hietala,Lena Bjarbo,Christopher Lindberg,Daniel Jons,Blanka Andersson,Ihsan Sengun,Pinar Ozcelik,Celal Tuga,Muzeyyen Ugur,Cavit Boz,Didem Altiparmak,Sibel Gazioglu,Cigdem Ozen Aydin,Sevim Erdem-Ozdamar,Can Ebru Bekircan-Kurt,Ezgi Yilmaz,Nazire Pinar Acar,Yagmur Caliskan,Husnu Efendi,Seda Aydinlik,Hakan Cavus,Cansu Semiz,Ozlem Tun,Murat Terzi,Baki Dogan,Musa Kazim Onar,Sedat Sen,Tugce Kirbas Cavdar,Fiona Norwood,Aikaterini Dimitriou,Jakit Gollogly,Mohamed Mahdi-Rogers,Arshira Seddigh,Gal Maier,Faisal Sohail,Sivakumar Sathasivam,Heike Arndt,Debbie Davies,Dave Watling,Michael H. Rivner,J. Edward Hartmann,Brandy Quarles,Nicole Smalley,Anthony A. Amato,Thomas Cochrane,Mohammed Salajegheh,Kristen Roe,Katherine Amato,Shirli Toska,Gil I. Wolfe,Nicholas Silvestri,Kara Patrick,Karen Zakalik,Jonathan S. Katz,Robert G. Miller,Marguerite Engel,Elena Bravver,Benjamin Rix Brooks,Sarah Plevka,Maryanne Burdette,Mohammad Sanjak,Megan Kramer,Joanne Nemeth,Clara Schommer,Vern C. Juel,Jeffrey T. Guptill,Lisa D. Hobson-Webb,Kate Beck,Donna Carnes,John Loor,Amanda Anderson,Dale J. Lange,Eliz Agopian,Jonathan Goldstein,Erin Manning,Lindsay Kaplan,Shara Holzberg,Nicole Kassebaum,Robert M. Pascuzzi,Cynthia Bodkin,John C. Kincaid,Riley Snook,Sandra Guinrich,Angela Micheels,Vinay Chaudhry,Andrea M. Corse,Betsy Mosmiller,Doreen Ho,Jayashri Srinivasan,Michael Vytopil,Nicholas Ventura,Stephanie Scala,Cynthia Carter,Craig Donahue,Carol Herbert,Elaine Weiner,Jonathan McKinnon,Laura Haar,Naya McKinnon,Karan Alcon,Kevin Daniels,Nadia Sattar,Dennis Jeffery,Kaitlyn McKenna,Amanda C. Guidon,William S. David,Christina Dheel,Mark Levine-Weinberg,Catherine Nigro,Ericka Simpson,Stanley H. Appel,Eugene Lai,Luis Lay,Milvia Pleitez,Sharon Halton,Casey Faigle,Lisa Thompson,Mark Sivak,Susan Shin,Joan Bratton,Daniel Jacobs,Gavin Brown,Ibrez Bandukwala,Morris Brown,Jennifer Kane,Ira Blount,Miriam Freimer,J. Chad Hoyle,Julie Agriesti,Julie Khoury,Tessa Marburger,Harpreet Kaur,Diana Dimitrova,Michelle Mellion,George Sachs,Brigid Crabtree,Roseann Keo,Ele Kim Perez,Sandra Taber,James Gilchrist,Angela Andoin,Taylor Darnell,Neelam Goyal,Sarada Sakamuri,Yuen T. So,Lesly Welsh,Ratna Bhavaraju-Sanka,Alejandro Tobon Gonzalez,Floyd Jones,Amy Saklad,Sharon P. Nations,Jaya Trivedi,Steve Hopkins,Mohamed Kazamel,Mohammad Alsharabati,Liang Lu,Sandi Mumfrey-Thomas,Amy Woodall,David P. Richman,Janelle Butters,Molly Lindsay,Tahseen Mozaffar,Tiyonnoh Cash,Namita Goyal,Gulmohor Roy,Veena Mathew,Fatima Maqsood,Brian Minton,H. James Jones,Jeffrey V. Rosenfeld,Rebekah Garcia,Sonia Garcia,Laura Echevarria,Michael Pulley,Shachie Aranke,Alan R. Berger,Jaimin Shah,Yasmeen Shabbir,Lisa Smith,Mary Varghese,Laurie Gutmann,Ludwig Gutmann,Andrea Swenson,Heena Olalde,Charlene Hafer-Macko,Justin Y. Kwan,Lindsay Zilliox,Karen Callison,Beth DiSanzo,Kerry Naunton,Martin Bilsker,Khema Sharma,Eliana Reyes,Anne Cooley,Sara-Claude Michon,Julie Steele,Chafic Karam,Manisha Chopra,Shawn J. Bird,Jacob Kaufman,Nichole Gallatti,Tuan Vu,Lara Katzin,Terry McClain,Brittany Harvey,Adam Hart,Kristin Huynh,Said R. Beydoun,Amaiak Chilingaryan,Brian Droker,Frank Lin,Akshay Shah,Anh Tran,Salma Akhter,Ali Malekniazi,Rup Tandan,Michael K. Hehir,Waqar Waheed,Shannon Lucy,Michael D. Weiss,Jane Distad,Sharon Downing,Susan Strom,Robert P. Lisak,Evanthia Bernitsas,Omar Khan,Shitiz Kumar Sriwastava,Alexandros Tselis,Kelly Jia,Tulio E. Bertorini,Thomas Arnold,Kendrick Henderson,Rekha Pillai,Ye Liu,Lauren Wheeler,Jasmine Hewlett,Mollie Vanderhook,Daniel DiCapua,Benison Keung,Aditya Kumar,Huned S. Patwa,Kimberly Robeson,Joan Nye,Hong Vu +623 more
TL;DR: A phase 3, randomised, double-blind, placebo-controlled, multicentre study in 76 hospitals and specialised clinics across North America, Latin America, Europe, and Asia to assess the efficacy and safety of eculizumab in patients with refractory myasthenia gravis.
Journal ArticleDOI
Neuromyelitis optica: Evaluation of 871 attacks and 1,153 treatment courses.
Ingo Kleiter,Anna Gahlen,Nadja Borisow,Katrin Fischer,Klaus-Dieter Wernecke,Brigitte Wegner,Kerstin Hellwig,Florence Pache,Klemens Ruprecht,Joachim Havla,Markus Krumbholz,Tania Kümpfel,Orhan Aktas,Hans-Peter Hartung,Marius Ringelstein,Christian Geis,Christoph Kleinschnitz,Achim Berthele,Bernhard Hemmer,Klemens Angstwurm,Jan-Patrick Stellmann,Simon Schuster,Martin Stangel,Florian Lauda,Hayrettin Tumani,Christoph Mayer,Lena Zeltner,Ulf Ziemann,Ralf A. Linker,Matthias Schwab,Martin Marziniak,Florian Then Bergh,Ulrich Hofstadt-van Oy,Oliver Neuhaus,Alexander Winkelmann,Wael Marouf,Jürgen H. Faiss,Brigitte Wildemann,Friedemann Paul,Sven Jarius,Corinna Trebst +40 more
TL;DR: The frequency, sequence, and efficacy of therapies used for NMO attacks are analyzed and it is shown that certain therapies are more effective than others in cases of severe N MO attacks.
Journal ArticleDOI
Astrocytes regulate myelin clearance through recruitment of microglia during cuprizone-induced demyelination
Thomas Skripuletz,Diane Hackstette,Katharina Bauer,Viktoria Gudi,Refik Pul,Elke Voss,Katharina Berger,Markus Kipp,Wolfgang Baumgärtner,Martin Stangel +9 more
TL;DR: Data demonstrate for the first time in vivo that astrocytes provide the signal environment that forms the basis for the recruitment of microglia to clear myelin debris, a process required for subsequent repair mechanisms in demyelinating diseases such as multiple sclerosis.