P
Peter S. Jensen
Researcher at Copenhagen University Hospital
Publications - 36
Citations - 866
Peter S. Jensen is an academic researcher from Copenhagen University Hospital. The author has contributed to research in topics: Serotonin transporter & Dopamine transporter. The author has an hindex of 16, co-authored 32 publications receiving 625 citations. Previous affiliations of Peter S. Jensen include Technical University of Denmark & University of Copenhagen.
Papers
More filters
Journal ArticleDOI
Role of Serotonin Transporter Changes in Depressive Responses to Sex-Steroid Hormone Manipulation: A Positron Emission Tomography Study
Vibe G. Frokjaer,Anja Pinborg,Klaus K. Holst,Agnete Overgaard,Susanne Henningsson,Maria Heede,Elisabeth Clare Larsen,Peter S. Jensen,Mikael Agn,Anna P. Nielsen,Dea S. Stenbæk,Sophie da Cunha-Bang,Szabolcs Lehel,Hartwig R. Siebner,Hartwig R. Siebner,Jens D. Mikkelsen,Claus Svarer,Gitte M. Knudsen +17 more
TL;DR: The data imply both serotonergic signaling and estradiol in the mechanisms by which sex-steroid hormone fluctuations provoke depressive symptoms and thus provide a rationale for future preventive strategies in high-risk groups.
Journal ArticleDOI
The Center for Integrated Molecular Brain Imaging (Cimbi) database
Gitte M. Knudsen,Peter S. Jensen,David Erritzoe,William F. C. Baaré,Anders Ettrup,Patrick M. Fisher,Nic Gillings,Hanne D. Hansen,Lars Kai Hansen,Steen G. Hasselbalch,Susanne Henningsson,Matthias M. Herth,Klaus K. Holst,Pernille Iversen,Lars Vedel Kessing,Julian Macoveanu,Kathrine Skak Madsen,Erik Lykke Mortensen,Finn Årup Nielsen,Olaf B. Paulson,Hartwig R. Siebner,Dea S. Stenbæk,Claus Svarer,Terry L. Jernigan,Stephen C. Strother,Vibe G. Frokjaer +25 more
TL;DR: A multimodality neuroimaging containing data from healthy volunteers and patients, acquired within the Lundbeck Foundation Center for Integrated Molecular Brain Imaging (Cimbi) in Copenhagen, Denmark, is described.
Journal ArticleDOI
Serotonin Transporters in Dopamine Transporter Imaging: A Head-to-Head Comparison of Dopamine Transporter SPECT Radioligands 123I-FP-CIT and 123I-PE2I
Morten Ziebell,Signe Holm-Hansen,Gerda Thomsen,Aase Wagner,Peter S. Jensen,Lars H. Pinborg,Gitte M. Knudsen +6 more
TL;DR: 123I-FP-CIT, but not 123I-PE2I, brain images have a highly interindividual but significant signal contribution from SERT, and both radioligands had approximately the same target-to-background ratios, but per injected megabecquerel, 123I/PE/CIT gave rise to 3-fold higher cerebral counting rates.
Journal ArticleDOI
Striatal dopamine transporter binding correlates with serum BDNF levels in patients with striatal dopaminergic neurodegeneration
Morten Ziebell,Usman Khalid,Anders B. Klein,Susana Aznar,Gerda Thomsen,Peter S. Jensen,Gitte M. Knudsen +6 more
TL;DR: It is found that in patients with striatal dopaminergic neurodegeneration serum BDNF levels decrease along with loss in striatal DAT binding, and a positive correlation between serumBDNF levels and striatalDAT availability is found.
Journal ArticleDOI
5-HTTLPR status predictive of neocortical 5-HT4 binding assessed with [(11)C]SB207145 PET in humans.
Patrick M. Fisher,Klaus K. Holst,Brenda Mc Mahon,Mette E. Haahr,Karine Madsen,Nic Gillings,William F. C. Baaré,Peter S. Jensen,Gitte M. Knudsen +8 more
TL;DR: Novel evidence supporting an effect of 5-HTTLPR status on serotonergic neurotransmission in adult humans is provided and this work is consistent with a model wherein the 5- HTTLPR S allele is associated with relatively increased serotonin levels.