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Pierre Bouchelouche

Researcher at University of Copenhagen

Publications -  27
Citations -  1570

Pierre Bouchelouche is an academic researcher from University of Copenhagen. The author has contributed to research in topics: Interstitial cystitis & Detrusor muscle. The author has an hindex of 13, co-authored 27 publications receiving 1456 citations.

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Identification of Tyrosine Residues in the Intracellular Domain of the Growth Hormone Receptor Required for Transcriptional Signaling and Stat5 Activation

TL;DR: It is demonstrated that specific tyrosines in the GH receptor are required for transcriptional signaling possibly by their role in the activation of transcription factor Stat5.
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Growth hormone receptor C-terminal domains required for growth hormone-induced intracellular free Ca2+ oscillations and gene transcription.

TL;DR: Findings indicate that the GHR can initiate two independent signaling pathways, one requiring the box 1 region and the other requiring the region between amino acids 454 and 506, and suggest that both of these pathways are required for GH-induced gene transcription.
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Human detrusor smooth muscle cells release interleukin-6, interleukin-8, and RANTES in response to proinflammatory cytokines interleukin-1β and tumor necrosis factor-α

TL;DR: It is demonstrated for the first time that HDSMCs release IL-8, IL-6, and RANTES in response to IL-1beta and TNF-alpha, suggesting that the human detrusor may contribute to mast cell infiltration into the bladder interstitium.