P
Ping Wei
Researcher at Fudan University
Publications - 54
Citations - 3234
Ping Wei is an academic researcher from Fudan University. The author has contributed to research in topics: Metastasis & Carcinogenesis. The author has an hindex of 26, co-authored 45 publications receiving 2283 citations. Previous affiliations of Ping Wei include University of Texas MD Anderson Cancer Center.
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Journal ArticleDOI
FoxM1 Promotes β-Catenin Nuclear Localization and Controls Wnt Target-Gene Expression and Glioma Tumorigenesis
Nu Zhang,Nu Zhang,Ping Wei,Ping Wei,Aihua Gong,Wen Tai Chiu,Hsueh Te Lee,Howard Colman,He Huang,Jianfei Xue,Mingguang Liu,Yong Wang,Raymond Sawaya,Keping Xie,Keping Xie,W. K. Alfred Yung,René H. Medema,Xi He,Suyun Huang,Suyun Huang +19 more
TL;DR: FoxM1 is a downstream component of Wnt signaling and is critical for β-catenin transcriptional function in tumor cells, and Wnt3a increases the level and nuclear translocation of FoxM1, which binds directly to β- catenin and enhances β-Catenin nuclear localization and transcriptional activity.
Journal ArticleDOI
A peptide encoded by circular form of LINC-PINT suppresses oncogenic transcriptional elongation in glioblastoma
Maolei Zhang,Kun Zhao,Xiaoping Xu,Yibing Yang,Sheng Yan,Sheng Yan,Ping Wei,Hui Liu,Jianbo Xu,Feizhe Xiao,Huangkai Zhou,Xuesong Yang,Nunu Huang,Jinglei Liu,Kejun He,Keping Xie,Gong Zhang,Suyun Huang,Nu Zhang +18 more
TL;DR: A 87-amino-acid peptide encoded by the circular form of the long intergenic non-protein-coding RNA p53-induced transcript (LINC-PINT) is identified that can reduce glioblastoma proliferation via interaction with PAF1 which sequentially inhibits the transcriptional elongation of some oncogenes.
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Tumor-derived exosomal miR-934 induces macrophage M2 polarization to promote liver metastasis of colorectal cancer
Senlin Zhao,Yushuai Mi,Bingjie Guan,Binbin Zheng,Ping Wei,Yanzi Gu,Zhengxiang Zhang,Sanjun Cai,Ye Xu,Xinxiang Li,Xuefeng He,Xinyang Zhong,Guichao Li,Zhiyu Chen,Dawei Li +14 more
TL;DR: A tumor and TAM interaction in the metastatic microenvironment mediated by tumor-derived exosomes that affects colorectal cancer liver metastasis and the present study provides a theoretical basis for secondary liver cancer.
Journal ArticleDOI
The lncRNA NEAT1 activates Wnt/β-catenin signaling and promotes colorectal cancer progression via interacting with DDX5.
Meng Zhang,Weiwei Weng,Qiongyan Zhang,Yong Wu,Shujuan Ni,Cong Tan,Midie Xu,Hui Sun,Chenchen Liu,Ping Wei,Xiang Du +10 more
TL;DR: The findings indicated that NEAT1 activated Wnt signaling to promote colorectal cancer progression and metastasis and theNEAT1/DDX5/Wnt/β-catenin axis could be a potential therapeutic target of pharmacological strategies.
Journal ArticleDOI
A Positive Feedback Loop of lncRNA-PVT1 and FOXM1 Facilitates Gastric Cancer Growth and Invasion.
Midie Xu,Yiqin Wang,Weiwei Weng,Ping Wei,Peng Qi,Qiongyan Zhang,Cong Tan,Shu Juan Ni,Lei Dong,Yusi Yang,Wanrun Lin,Qinghua Xu,Dan Huang,Zhaohui Huang,Yuqing Ma,Wei Zhang,Weiqi Sheng,Xiang Du +17 more
TL;DR: PVT1 may be a valuable prognostic predictor for gastric cancer, and the positive feedback loop of PVT1-FOXM1 could be a therapeutic target in pharmacologic strategies.