P
Pouya Movahed
Researcher at Lund University
Publications - 9
Citations - 1548
Pouya Movahed is an academic researcher from Lund University. The author has contributed to research in topics: TRPV1 & Capsazepine. The author has an hindex of 7, co-authored 9 publications receiving 1459 citations.
Papers
More filters
Journal ArticleDOI
Pungent products from garlic activate the sensory ion channel TRPA1
Diana M. Bautista,Pouya Movahed,Andrew Hinman,Helena E. Axelsson,Olov Sterner,Edward D. Högestätt,David Julius,Sven-Eric Jordt,Peter M. Zygmunt +8 more
TL;DR: It is shown that allicin and DADS excite an allyl isothiocyanate-sensitive subpopulation of sensory neurons and induce vasodilation by activating capsaicin-sensitive perivascular sensory nerve endings, suggesting that garlic excites sensory neurons primarily through activation of TRPA1.
Journal ArticleDOI
The anandamide transport inhibitor AM404 activates vanilloid receptors.
TL;DR: In conclusion, AM404 activates native and cloned vanilloid receptors and causes vasodilation in rat isolated hepatic artery contracted with phenylephrine.
Journal ArticleDOI
Endogenous unsaturated C18 N-acylethanolamines are vanilloid receptor (TRPV1) agonists.
Pouya Movahed,Bo A. G. Jönsson,Bryndis Birnir,Johan Wingstrand,Tino Dyhring Jørgensen,Anna Ermund,Olov Sterner,Peter M. Zygmunt,Edward D. Högestätt +8 more
TL;DR: It is shown that several endogenous non-cannabinoid NAEs, many of which are more abundant than anandamide in rat tissues, activate TRPV1 and thus may play a role as endogenous TRPv1 modulators.
Journal ArticleDOI
Monoacylglycerols Activate TRPV1-A Link between Phospholipase C and TRPV1
Peter M. Zygmunt,Anna Ermund,Pouya Movahed,David Andersson,Charlotte Simonsen,Bo A. G. Jönsson,Anders Blomgren,Bryndis Birnir,Stuart Bevan,Alain Eschalier,Alain Eschalier,Christophe Mallet,Christophe Mallet,Ana Gomis,Edward D. Högestätt +14 more
TL;DR: Results show that intact 2-arachidonoylglycerol and 1-arachesionoyl Glycerol are endogenous TRPV1 activators, contributing to phospholipase C-dependent TRP V1 channel activation and TRPv1-mediated antinociceptive signaling in the brain.
Journal ArticleDOI
Vanilloid receptors on capsaicin-sensitive sensory nerves mediate relaxation to methanandamide in the rat isolated mesenteric arterial bed and small mesenteric arteries.
Vera Ralevic,David A. Kendall,Michael D. Randall,Peter M. Zygmunt,Pouya Movahed,Edward D. Högestätt +5 more
TL;DR: It is shown that vanilloid receptors on capsaicin‐sensitive sensory nerves play an important role in the vasorelaxant action of methanandamide in the rat isolated mesenteric arterial bed and small mesenteri arterial segments.