P
Priyanka Rashmi
Researcher at University of California, San Francisco
Publications - 16
Citations - 204
Priyanka Rashmi is an academic researcher from University of California, San Francisco. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 4, co-authored 10 publications receiving 143 citations. Previous affiliations of Priyanka Rashmi include Harvard University.
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Journal ArticleDOI
mTORC2 regulates renal tubule sodium uptake by promoting ENaC activity.
Catherine E. Gleason,Gustavo Frindt,Chih-Jen Cheng,Chih-Jen Cheng,Michael Ng,Atif Kidwai,Atif Kidwai,Priyanka Rashmi,Florian Lang,Michel Baum,Lawrence G. Palmer,David A. Pearce +11 more
TL;DR: It is demonstrated that mTOR regulates kidney tubule ion handling and suggest that m TOR regulates Na+ homeostasis through SGK1-dependent modulation of ENaC activity.
Journal ArticleDOI
Proteasomal degradation of Nck1 but not Nck2 regulates RhoA activation and actin dynamics
Lisa Buvall,Priyanka Rashmi,Priyanka Rashmi,Esther Lopez-Rivera,Svetlana Andreeva,Astrid Weins,Astrid Weins,Hanna Wallentin,Anna Greka,Peter Mundel +9 more
TL;DR: Findings reveal proteasomal regulation as a key factor in the distinct and non-redundant effects of Nck on RhoA-mediated actin dynamics.
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Rescue of tropomyosin deficiency in Drosophila and human cancer cells by synaptopodin reveals a role of tropomyosin α in RhoA stabilization
Jenny Wong,Elizabeth Iorns,Michelle N. Rheault,Toby M. Ward,Priyanka Rashmi,Ursula Weber,Marc E. Lippman,Christian Faul,Marek Mlodzik,Peter Mundel +9 more
TL;DR: It is shown that synaptopodin has a shorter half‐life but shares functional properties with the highly stable tropomyosin, and elucidate RhoA stabilization by structurally unrelated actin‐binding proteins as a conserved mechanism for regulation of stress fibre dynamics and cell motility in a cell type‐specific fashion.
Journal ArticleDOI
Glucocorticoid-induced leucine zipper protein regulates sodium and potassium balance in the distal nephron
TL;DR: Evidence is provided supporting a role for GILZ in modulating the balance of renal sodium and potassium excretion by regulating the sodium-chloride cotransporter (NCC) activity in the distal nephron by inhibiting SPAK phosphorylation.
Journal ArticleDOI
Near-Single-Cell Proteomics Profiling of the Proximal Tubular and Glomerulus of the Normal Human Kidney.
Tara K. Sigdel,Paul D. Piehowski,Sudeshna Roy,Juliane Liberto,Joshua R. Hansen,Adam C. Swensen,Rui Zhao,Ying Zhu,Priyanka Rashmi,Andrew Schroeder,Izabella Damm,Swastika Sur,Jinghui Luo,Yingbao Yang,Wei-Jun Qian,Minnie M. Sarwal +15 more
TL;DR: This pilot study provides the roadmap for application of the near-single-cell proteomics workflow for analysis of other renal micro-compartments, on a larger scale, to unravel perturbations of renal sub-cellular function in the normal kidney as well as different etiologies of acute and chronic kidney disease.