R
R Geoffrey Burwell
Researcher at University of Nottingham
Publications - 18
Citations - 1024
R Geoffrey Burwell is an academic researcher from University of Nottingham. The author has contributed to research in topics: Scoliosis & Cobb angle. The author has an hindex of 12, co-authored 18 publications receiving 863 citations. Previous affiliations of R Geoffrey Burwell include Nottingham University Hospitals NHS Trust.
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Journal ArticleDOI
Adolescent idiopathic scoliosis.
Jack C. Y. Cheng,René M. Castelein,Winnie C.W. Chu,Aina J. Danielsson,Aina J. Danielsson,Matthew B. Dobbs,Theodoros B Grivas,Christina A. Gurnett,Keith D. K. Luk,Alain Moreau,Peter O. Newton,Peter O. Newton,Ian A. F. Stokes,Stuart L. Weinstein,R Geoffrey Burwell +14 more
TL;DR: Both the prevention of AIS and the treatment of its direct underlying cause are not possible, because the definite aetiology and aetiopathogenetic mechanisms that underlie AIS are still unclear.
Journal ArticleDOI
Pathogenesis of adolescent idiopathic scoliosis in girls - a double neuro-osseous theory involving disharmony between two nervous systems, somatic and autonomic expressed in the spine and trunk: possible dependency on sympathetic nervous system and hormones with implications for medical therapy
R Geoffrey Burwell,R K Aujla,M.P. Grevitt,Peter Dangerfield,Alan Moulton,Tabitha Randell,Susan I. Anderson +6 more
TL;DR: A speculative pathogenetic theory is formulated that AIS in girls results from developmental disharmony expressed in spine and trunk between autonomic and somatic nervous systems, and implications are discussed for neuroendocrine dysfunctions, osteopontin, sympathoactivation, medical therapy, Rett and Prader-Willi syndromes, infantile idiopathic scoliosis, and human evolution.
Journal ArticleDOI
Adolescent idiopathic scoliosis (AIS), environment, exposome and epigenetics: a molecular perspective of postnatal normal spinal growth and the etiopathogenesis of AIS with consideration of a network approach and possible implications for medical therapy
R Geoffrey Burwell,Peter Dangerfield,Peter Dangerfield,Peter Dangerfield,Alan Moulton,Theodoros B Grivas +5 more
TL;DR: A new term and concept pathophysiologic scoliogenic exposome is proposed for the abnormal processes in molecular pathways particularly of the internal environment currently expressed as etiopathogenetic hypotheses; these are suggested to have deforming effects on the growth plates of vertebrae at cell, tissue, structure and/or organ levels that are considered to be epigenetic.
Journal ArticleDOI
Patient and Parental Perception of Adolescent Idiopathic Scoliosis Before and After Surgery in Comparison with Surface and Radiographic Measurements
TL;DR: Back pain and ODI were unchanged, but concerns regarding scoliosis were reduced, and the preoperative surface asymmetry score correlated with the patients' grading of their rib-hump.
Journal ArticleDOI
Relative shortening and functional tethering of spinal cord in adolescent scoliosis - Result of asynchronous neuro-osseous growth, summary of an electronic focus group debate of the IBSE.
Winnie C.W. Chu,Wynnie Wai-mam Lam,Bobby K. W. Ng,Lam Tze-ping,Kwong Man Lee,Xia Guo,Jack C. Y. Cheng,R Geoffrey Burwell,Peter Dangerfield,Tim Jaspan +9 more
TL;DR: Examining the spinal cord to vertebral growth interaction during adolescence in scoliosis supports and develops the Roth-Porter concept of uncoupled neuro-osseous growth in the pathogenesis of AIS, and responds to five other concepts of pathogenesis for AIS and suggests that relative anterior spinal overgrowth and biomechanical growth modulation may also contribute to AIS pathogenesis.