R
Raj K. Kurupati
Researcher at Wistar Institute
Publications - 36
Citations - 1288
Raj K. Kurupati is an academic researcher from Wistar Institute. The author has contributed to research in topics: Vaccination & Influenza vaccine. The author has an hindex of 15, co-authored 35 publications receiving 984 citations. Previous affiliations of Raj K. Kurupati include Council of Scientific and Industrial Research & University of Delhi.
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Journal ArticleDOI
Enhancing CD8 + T Cell Fatty Acid Catabolism within a Metabolically Challenging Tumor Microenvironment Increases the Efficacy of Melanoma Immunotherapy.
Ying Zhang,Ying Zhang,Raj K. Kurupati,Ling Liu,Xiangyang Zhou,Gao Zhang,Abeer Hudaihed,Flavia Filisio,Wynetta Giles-Davis,Xiaowei Xu,Giorgos C. Karakousis,Lynn M. Schuchter,Wei Xu,Ravi K. Amaravadi,Min Xiao,Norah Sadek,Clemens Krepler,Meenhard Herlyn,Gordon J. Freeman,Joshua D. Rabinowitz,Hildegund C.J. Ertl +20 more
TL;DR: Using mouse melanoma models, it is reported that CD8+ TILs enhance peroxisome proliferator-activated receptor (PPAR)-α signaling and catabolism of fatty acids (FAs) when simultaneously subjected to hypoglycemia and hypoxia.
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Circulating CXCR5+PD-1+ Response Predicts Influenza Vaccine Antibody Responses in Young Adults but not Elderly Adults
Ramin S. Herati,Morgan A. Reuter,Douglas V. Dolfi,Kathleen D. Mansfield,Htin Aung,Osama Z. Badwan,Raj K. Kurupati,S. Kannan,Hildegund C.J. Ertl,Kenneth E. Schmader,Michael R. Betts,David H. Canaday,E. John Wherry +12 more
TL;DR: Future rational vaccine design efforts should incorporate Tfh measurement as an immune correlate of protection, particularly in the setting of aging.
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Adenovirus-Based Vaccines: Comparison of Vectors from Three Species of Adenoviridae
Horng-Shen Chen,Zhiquan Xiang,Yan Li,Raj K. Kurupati,B. Jia,B. Jia,Ang Bian,Dongming Zhou,Natalie A. Hutnick,S. Yuan,Clive M. Gray,Jennifer Serwanga,B Auma,Pontiano Kaleebu,Xiangyang Zhou,Michael R. Betts,Hildegund C.J. Ertl +16 more
TL;DR: The results suggest that the potential of AdHu26 as a vaccine vector may suffer from limitations similar to those found for vectors based on other prevalent human Ads.
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A unique and highly efficient non-viral DNA/siRNA delivery system based on PEI-bisepoxide nanoparticles.
TL;DR: A highly efficient delivery system using 1,4-butanediol diglycidyl ether (bisepoxide) crosslinked polyethylenimine (PEI) nanoparticles (PN) was found to deliver siRNA efficiently into HEK cells, resulting in approximately 70% suppression of the targetted gene (GFP).
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Properties of Bacillus anthracis spores prepared under various environmental conditions
Renu B. Baweja,Mohd Saif Zaman,Abid R. Mattoo,Kirti Sharma,Vishwas Tripathi,Anita Aggarwal,Gyanendra P. Dubey,Raj K. Kurupati,Munia Ganguli,Nabo Kumar Chaudhury,Somdutta Sen,Taposh K. Das,W. N. Gade,Yogendra Singh +13 more
TL;DR: Temperature, pH and nutrient availability during sporulation affect properties of B. anthracis spores, and the dipicolinic acid content and germination efficiency was highest in spores formed at 45°C.