R
Ralph J. DiLeone
Researcher at Yale University
Publications - 115
Citations - 15894
Ralph J. DiLeone is an academic researcher from Yale University. The author has contributed to research in topics: Nucleus accumbens & Lateral hypothalamus. The author has an hindex of 55, co-authored 109 publications receiving 14363 citations. Previous affiliations of Ralph J. DiLeone include Stanford University & University of Texas Southwestern Medical Center.
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Book ChapterDOI
Primate models of schizophrenia: future possibilities
TL;DR: Primate models may be particularly important in determining the functional impact of genetic changes in patients with schizophrenia, as their effects may be magnified in the extensively connected primate neurons.
Journal ArticleDOI
Innate Fear-Induced Weight Regulation in the C57BL/6J Mouse.
TL;DR: A simplified and robust laboratory model of predation-mediated weight regulation with inbred lab mice and fear-inducing odor is established, and a likely, yet undetermined, metabolic adaptation is suggested as contributing to this response.
Journal ArticleDOI
Down-regulation of miRNAs in the brain and development of diet-induced obesity.
TL;DR: Data show that miR‐155 is physiologically down‐regulated after intake of an obesogenic diet, and that loss of miR-155 increases intake ofAn obesogenically‐induced obesity, and shed light on a potential miRNA‐based mechanism contributing to the development of diet‐induced Obesity.
Vitamin D3: A Role in Dopamine Circuit Regulation, Diet-Induced Obesity, and Drug
Joseph R. Trinko,Benjamin B. Land,W. Solecki,Robert J. Wickham,Luis A. Tellez,Jaime G. Maldonado-Avilés,Ivan E. de Araujo,Nii A. Addy,Ralph J. DiLeone +8 more
TL;DR: It is suggested that reduced dietary D3 may be a contributing environmental factor enhancing DIO as well as drug intake while eating a high fat diet and that dopamine circuits are modulated by D3 signaling, and may serve as direct or indirect targets for exogenous calcitriol.
Journal ArticleDOI
The response to prolonged fasting in hypothalamic serotonin transporter availability is blunted in obesity.
Katy A. van Galen,Jan Booij,Anouk Schrantee,Sofie M. Adriaanse,Unga A. Unmehopa,Eric Fliers,Gary J. Schwartz,Ralph J. DiLeone,Kasper W. ter Horst,Susanne E. la Fleur,Susanne E. la Fleur,Mireille J. Serlie +11 more
TL;DR: In this article, the effects of 12 vs 24h of fasting on SERT and DAT availability in the hypothalamus/thalamic and striatum, respectively, using SPECT imaging in 10 lean men and 10 men with obesity.