R
Ram Malladi
Researcher at Queen Elizabeth Hospital Birmingham
Publications - 75
Citations - 1663
Ram Malladi is an academic researcher from Queen Elizabeth Hospital Birmingham. The author has contributed to research in topics: Transplantation & Medicine. The author has an hindex of 16, co-authored 60 publications receiving 1071 citations. Previous affiliations of Ram Malladi include University Hospitals Birmingham NHS Foundation Trust & University of Birmingham.
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Journal ArticleDOI
Azacitidine augments expansion of regulatory T cells after allogeneic stem cell transplantation in patients with acute myeloid leukemia (AML)
Oliver Goodyear,Michael Dennis,Nadira Y. Jilani,Nadira Y. Jilani,Justin Loke,Shamyla Siddique,Shamyla Siddique,Gordon B. Ryan,Jane Nunnick,Jane Nunnick,Rahela Khanum,Manoj Raghavan,Manoj Raghavan,Mark Cook,John A. Snowden,Mike Griffiths,Nigel H. Russell,John A. Liu Yin,Charles Crawley,Gordon Cook,Paresh Vyas,Paul Moss,Ram Malladi,Ram Malladi,Charles Craddock,Charles Craddock +25 more
TL;DR: Data support the further examination of AZA after transplantation as a mechanism of augmenting a GVL effect without a concomitant increase in GVHD.
Journal ArticleDOI
Prophylaxis and management of graft versus host disease after stem-cell transplantation for haematological malignancies: updated consensus recommendations of the European Society for Blood and Marrow Transplantation
Olaf Penack,Monia Marchetti,Tapani Ruutu,Mahmoud Aljurf,Andrea Bacigalupo,Francesca Bonifazi,Fabio Ciceri,Jan J. Cornelissen,Ram Malladi,Rafael F. Duarte,Sebastian Giebel,Hildegard T. Greinix,Ernst Holler,Anita Lawitschka,Stephan Mielke,Mohamad Mohty,Mutlu Arat,Arnon Nagler,Jakob Passweg,Hélène Schoemans,Gérard Socié,Carlos Solano,Radovan Vrhovac,Robert Zeiser,Nicolaus Kröger,Grzegorz W. Basak +25 more
TL;DR: Key updates to these recommendations include a broader use of rabbit anti-T-cell globulin; lower steroid doses for the management of grade 2 acute GVHD with isolated skin or upper gastrointestinal tract manifestations; fluticasone, azithromycin, and montelukast should be used for bronchiolitis obliterans syndrome; and the addition of newer treatment options for resteroid-refractory acute and chronic GV HD.
Journal ArticleDOI
Tolerability and Clinical Activity of Post-Transplantation Azacitidine in Patients Allografted for Acute Myeloid Leukemia Treated on the RICAZA Trial
Charles Craddock,Charles Craddock,Nadira Y. Jilani,Nadira Y. Jilani,Shamyla Siddique,Shamyla Siddique,Christina Yap,Christina Yap,Josephine Khan,Sandeep Nagra,Janice Ward,Paul Ferguson,Paul Ferguson,Peter Hazlewood,Peter Hazlewood,Richard Buka,Paresh Vyas,Oliver Goodyear,Eleni Tholouli,Charles Crawley,Nigel H. Russell,Jenny Byrne,Ram Malladi,Ram Malladi,John A. Snowden,Michael Dennis +25 more
TL;DR: AZA is well tolerated after transplantation and appears to have the capacity to reduce the relapse risk in patients who demonstrate a CD8+ T cell response to tumor antigens, although these observations require confirmation in a prospective clinical trial.
Journal ArticleDOI
The role of extracorporeal photopheresis in the management of cutaneous T-cell lymphoma, graft-versus-host disease and organ transplant rejection: a consensus statement update from the UK Photopheresis Society
Arun Alfred,Peter C. Taylor,Fiona L Dignan,Khaled El-Ghariani,James E. Griffin,Andrew R. Gennery,Denise Bonney,Emma Das-Gupta,Sarah Lawson,Ram Malladi,Kenneth W. Douglas,Tracey Maher,J Guest,Laura Hartlett,Andrew J. Fisher,Fiona Child,Julia Scarisbrick +16 more
TL;DR: This consensus statement updates the previous statement from 2007 on the treatment of CTCL and GvHD with ECP using evidence based medicine and best medical practise and includes guidelines for both children and adults.
Journal ArticleDOI
Augmented Reduced-Intensity Regimen Does Not Improve Postallogeneic Transplant Outcomes in Acute Myeloid Leukemia.
Charles Craddock,Charles Craddock,Aimee Jackson,Justin Loke,Shamyla Siddique,Andrea Hodgkinson,John Mason,Georgia Andrew,Sandeep Nagra,Ram Malladi,Andrew Peniket,Maria H. Gilleece,Rahuman Salim,Eleni Tholouli,Victoria T Potter,Charles Crawley,Keith Wheatley,Rachel Protheroe,Paresh Vyas,Ann Hunter,Anne Parker,Keith G. Wilson,Jiri Pavlu,Jenny Byrne,Richard Dillon,Naeem Khan,Nicholas I. McCarthy,Sylvie D. Freeman +27 more
TL;DR: In this paper, the curative potential of allogeneic stem-cell transplantation to older adults with high-risk acute myeloid leukemia (AML) and mye...