R
Ramneek Gupta
Researcher at Technical University of Denmark
Publications - 97
Citations - 12141
Ramneek Gupta is an academic researcher from Technical University of Denmark. The author has contributed to research in topics: Genome-wide association study & Population. The author has an hindex of 34, co-authored 92 publications receiving 10432 citations. Previous affiliations of Ramneek Gupta include The Breast Cancer Research Foundation & Novo Nordisk.
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Prediction of post-translational glycosylation and phosphorylation of proteins from the amino acid sequence.
TL;DR: A new method for kinase‐specific prediction of phosphorylation sites, NetPhosK, is presented, which extends the earlier and more general tool, netPhos, and the issues of underestimation, over‐prediction and strategies for improving prediction specificity are discussed.
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Precision mapping of the human O-GalNAc glycoproteome through SimpleCell technology
Catharina Steentoft,Sergey Y. Vakhrushev,Hiren J. Joshi,Hiren J. Joshi,Yun Kong,Malene Bech Vester-Christensen,Katrine T. Schjoldager,Kirstine Lavrsen,Sally Dabelsteen,Nis Borbye Pedersen,Lara Marcos-Silva,Lara Marcos-Silva,Ramneek Gupta,Eric P. Bennett,Ulla Mandel,Søren Brunak,Søren Brunak,Hans H. Wandall,Steven B. Levery,Henrik Clausen +19 more
TL;DR: A genetic engineering approach using human cell lines to simplify O‐glycosylation (SimpleCells) that enables proteome‐wide discovery of O-glycan sites using ‘bottom‐up’ ETD‐based mass spectrometric analysis and an improved NetOGlyc4.0 model for prediction of O‐ Glycoproteins.
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Prediction, conservation analysis, and structural characterization of mammalian mucin-type O-glycosylation sites
TL;DR: NetOGlyc 3.1 can predict sites for completely new proteins without losing its performance, indicating that mucin-type glycosylation in most cases is a bulk property and not a very site-specific one.
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Analysis and prediction of leucine-rich nuclear export signals
TL;DR: A thorough analysis of nuclear export signals and a prediction server is presented, which shows that the most important properties of NESs are accessibility and flexibility allowing relevant proteins to interact with the signal.
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Ancient human genome sequence of an extinct Palaeo-Eskimo
Morten Rasmussen,Yingrui Li,Stinus Lindgreen,Jakob Skou Pedersen,Anders Albrechtsen,Ida Moltke,Mait Metspalu,Ene Metspalu,Toomas Kivisild,Toomas Kivisild,Ramneek Gupta,Marcelo Bertalan,Kasper Nielsen,M. Thomas P. Gilbert,Yong Wang,Maanasa Raghavan,Maanasa Raghavan,Paula F. Campos,Hanne Munkholm Kamp,Andrew Wilson,Andrew Gledhill,Silvana R. Tridico,Silvana R. Tridico,Michael Bunce,Eline D. Lorenzen,Jonas Binladen,Xiaosen Guo,Jing Zhao,Xiuqing Zhang,Hao Zhang,Zhuo Li,Minfeng Chen,Ludovic Orlando,Karsten Kristiansen,Mads Bak,Niels Tommerup,Christian Bendixen,Tracey Pierre,Bjarne Grønnow,Morten Meldgaard,Claus Andreasen,S. A. Fedorova,S. A. Fedorova,Ludmila P. Osipova,Thomas Higham,Christopher Bronk Ramsey,Thomas Hansen,Finn Cilius Nielsen,Michael H. Crawford,Søren Brunak,Søren Brunak,Thomas Sicheritz-Pontén,Richard Villems,Rasmus Nielsen,Rasmus Nielsen,Anders Krogh,Jun Wang,Eske Willerslev +57 more
TL;DR: This genome sequence of an ancient human obtained from ∼4,000-year-old permafrost-preserved hair provides evidence for a migration from Siberia into the New World some 5,500 years ago, independent of that giving rise to the modern Native Americans and Inuit.