R
Ranajit Pal
Researcher at University of Virginia
Publications - 118
Citations - 5361
Ranajit Pal is an academic researcher from University of Virginia. The author has contributed to research in topics: Simian immunodeficiency virus & Virus. The author has an hindex of 43, co-authored 118 publications receiving 5202 citations. Previous affiliations of Ranajit Pal include National Institutes of Health.
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Journal ArticleDOI
Growth of macrophage-tropic and primary human immunodeficiency virus type 1 (HIV-1) isolates in a unique CD4+ T-cell clone (PM1): failure to downregulate CD4 and to interfere with cell-line-tropic HIV-1.
Paolo Lusso,F. Cocchi,C Balotta,P. D. Markham,A. Louie,P. Farci,Ranajit Pal,Robert C. Gallo,Marvin S. Reitz +8 more
TL;DR: Resistent with the lack of CD4 downregulation, persistent infection of PM1 by HIV-1BaL or HIV-2(573) failed to interfere with HIV-3IIIB superinfection, suggesting that a direct viral interaction may occur in vivo between biologically diverse HIV- 1 strains.
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ALVAC-SIV-gag-pol-env-Based Vaccination and Macaque Major Histocompatibility Complex Class I (A*01) Delay Simian Immunodeficiency Virus SIVmac-Induced Immunodeficiency
Ranajit Pal,David Venzon,Norman L. Letvin,Sampa Santra,David C. Montefiori,N. R. Miller,Elzbieta Tryniszewska,Mark G. Lewis,Thomas C. VanCott,Vanessa M. Hirsch,Ruth A. Woodward,A. Gibson,M. Grace,E. Dobratz,P. D. Markham,Zdeněk Hel,Janos Nacsa,Michel Klein,Jim Tartaglia,Genoveffa Franchini +19 more
TL;DR: It is reported that both inherent, host-dependentimmune responses to SIVmac251 infection and vaccination-induced immune responses to viral antigens were able to reduce virus replication and/or CD4+ T-cell loss.
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Cross-subtype antibody and cellular immune responses induced by a polyvalent DNA prime–protein boost HIV-1 vaccine in healthy human volunteers
Shixia Wang,Jeffrey S. Kennedy,Kim West,David C. Montefiori,Scott Coley,John M. Lawrence,Siyuan Shen,Sharone Green,Alan L. Rothman,Francis A. Ennis,James Arthos,Ranajit Pal,Phillip D. Markham,Shan Lu +13 more
TL;DR: It is demonstrated that the DNA prime-protein boost approach is an effective immunization method to elicit both humoral and cell-mediated immune responses in humans, and that a polyvalent Env formulation could generate broad immune responses against HIV-1 viruses with diverse genetic backgrounds.
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Inhibition of HIV-1 Infection by the β-Chemokine MDC
Ranajit Pal,Alfredo Garzino-Demo,P D Markham,Jennifer M. Burns,Michelle Brown,Robert C. Gallo,Anthony L. DeVico +6 more
TL;DR: In this paper, the β-chemokine macrophage-derived chemokine (MDC) was identified as responsible for a major proportion of HIV-1-specific suppressor activity produced by primary T cells.
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Prevention of vaginal SHIV transmission in macaques by a live recombinant Lactobacillus
Laurel A. Lagenaur,Brigitte E Sanders-Beer,Beda Brichacek,Ranajit Pal,Xiaowen Liu,Yang Liu,Rosa R. Yu,David Venzon,Peter P. Lee,Dean H. Hamer +9 more
TL;DR: A 63% reduction in transmission of a chimeric simian/HIV (SHIVSF162P3) after repeated vaginal challenges of macaques treated with Lactobacillus jensenii expressing the HIV-1 entry inhibitor cyanovirin-N.