Raoul Belzeaux

TL;DR: The results highlight the importance of studies investigating the tight relationship between peripheral transcriptional changes and the dynamic clinical progression of MDE patients to provide biomarkers of Mde evolution and prognosis.

TL;DR: A new functional magnetic resonance imaging paradigm varying 3 parameters: emotional valence, emotional congruency, and allocation of attention is used to distinguish the functional variation in activity and connectivity between amygdala, anterior cingulate cortex (ACC), and dorsolateral prefrontal cortex (DLPFC).

TL;DR: The validation of a common inpatient satisfaction instrument is a major challenge and recommendations for the future development of satisfaction instruments may include: item generation based exclusively on the patient's point of view; a validation process on a large and representative population; and an instrument combining generic and specific approaches.

TL;DR: PBMCs obtained at different time points during MDE progression represent a promising avenue to discover biological markers for depression, and 5HTT exhibited a strong correlation with clinical score evolution.

TL;DR: Findings suggest that in addition to the deletion conferring a greatly increased risk to schizophrenia, the risk is higher when the 22q11.2 deletion and common polygenic risk factors that contribute to schizophrenia in the general population are both present.