R
Raquel Mejías-Luque
Researcher at Technische Universität München
Publications - 48
Citations - 1661
Raquel Mejías-Luque is an academic researcher from Technische Universität München. The author has contributed to research in topics: Helicobacter pylori & Immune system. The author has an hindex of 21, co-authored 37 publications receiving 1263 citations. Previous affiliations of Raquel Mejías-Luque include Ludwig Maximilian University of Munich.
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Journal ArticleDOI
Helicobacter pylori adhesin HopQ engages in a virulence-enhancing interaction with human CEACAMs
Anahita Javaheri,Tobias Kruse,Kristof Moonens,Raquel Mejías-Luque,Ayla Debraekeleer,Carmen Isabell Asche,Nicole Tegtmeyer,Behnam Kalali,Nina C. Bach,Stephan A. Sieber,Darryl J. Hill,Verena Königer,Christof R. Hauck,Roman Andriiovych Moskalenko,Rainer Haas,Dirk H. Busch,Esther Klaile,Hortense Slevogt,Alexej Schmidt,Alexej Schmidt,Steffen Backert,Han Remaut,Bernhard B. Singer,Markus Gerhard +23 more
TL;DR: The data suggest the HopQ–CEACAM1 interaction to be a potentially promising novel therapeutic target to combat H. pylori-associated diseases.
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Effect of Helicobacter pylori on gastrointestinal microbiota: a population-based study in Linqu, a high-risk area of gastric cancer
Yang Guo,Yang Zhang,Markus Gerhard,Juan-Juan Gao,Raquel Mejías-Luque,Lian Zhang,Michael Vieth,Jun-Ling Ma,Monther Bajbouj,Stepan Suchanek,Wei-Dong Liu,Kurt Ulm,Michael Quante,Zhe-Xuan Li,Tong Zhou,Roland M. Schmid,Meinhard Classen,Wen-Qing Li,Wei-Cheng You,Kai-Feng Pan +19 more
TL;DR: It is revealed that the dysbiotic microbiota in H. pylori positive mucosa was associated with advanced gastric lesions and could be reversed by eradication and shows beneficial effects on gut microbiota.
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SOX2 expression correlates with lymph-node metastases and distant spread in right-sided colon cancer.
Jens Neumann,Fiorina Bahr,David Horst,David Horst,Lydia Kriegl,Jutta Engel,Raquel Mejías-Luque,Markus Gerhard,Thomas Kirchner,Andreas Jung +9 more
TL;DR: It is demonstrated that increased expression of either SOX2 or nuclear β-catenin are associated with distant metastases in right-sided CC andSOX2 is also associated with lymph-node metastases, highlighting the importance of stemness-associated markers for the identification of CC with high risk for distant spread.
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Helicobacter pylori–Induced IL-1β Secretion in Innate Immune Cells Is Regulated by the NLRP3 Inflammasome and Requires the Cag Pathogenicity Island
Raphaela P. Semper,Raquel Mejías-Luque,Christina J. Groß,Florian Anderl,Anne Müller,Michael Vieth,Dirk H. Busch,Clarissa Prazeres da Costa,Jürgen Ruland,Olaf Groß,Markus Gerhard +10 more
TL;DR: In vivo experiments indicate an important role for the inflammasome in the onset and establishment of H. pylori infection and in the subsequent inflammatory response of the host.
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H. pylori Virulence Factors: Influence on Immune System and Pathology
TL;DR: In this article, a review aims to pinpoint some potentially important angles, which have to be considered mutually when studying H. pylori's pathogenicity, and discuss the recent experimental proofs of the "hygiene hypothesis" in correlation with Helicobacter's infection, which adds another aspect of complexity to this infection.