R
Ricardo U. Sorensen
Researcher at Louisiana State University
Publications - 151
Citations - 10068
Ricardo U. Sorensen is an academic researcher from Louisiana State University. The author has contributed to research in topics: Antibody & Antigen. The author has an hindex of 40, co-authored 151 publications receiving 9370 citations. Previous affiliations of Ricardo U. Sorensen include LSU Health Sciences Center New Orleans & Boston Children's Hospital.
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Journal ArticleDOI
Insertional oncogenesis in 4 patients after retrovirus-mediated gene therapy of SCID-X1
Salima Hacein-Bey-Abina,Alexandrine Garrigue,Gary P. Wang,Jean Soulier,Annick Lim,Estelle Morillon,Emmanuelle Clappier,Laure Caccavelli,Eric Delabesse,Kheira Beldjord,Vahid Asnafi,Elizabeth Macintyre,Liliane Dal Cortivo,Isabelle Radford,Nicole Brousse,François Sigaux,Despina Moshous,Julia Hauer,Arndt Borkhardt,Bernd H. Belohradsky,Uwe Wintergerst,Maria C. Velez,Lily E. Leiva,Ricardo U. Sorensen,NM Wulffraat,Stéphane Blanche,Frederic D. Bushman,Alain Fischer,Marina Cavazzana-Calvo +28 more
TL;DR: These findings functionally specify a genetic network that controls growth in T cell progenitors and led to sustained remission in 3 of the 4 cases of T cell leukemia, but failed in the fourth.
Journal ArticleDOI
Sustained Correction of X-Linked Severe Combined Immunodeficiency by ex Vivo Gene Therapy
Salima Hacein-Bey-Abina,Françoise Le Deist,Frédérique Carlier,Cécile Bouneaud,Christophe Hue,Jean-Pierre de Villartay,Adrian J. Thrasher,NM Wulffraat,Ricardo U. Sorensen,Sophie Dupuis-Girod,Alain Fischer,E. Graham Davies,Wietse Kuis,Lilly Leiva,Marina Cavazzana-Calvo +14 more
TL;DR: Ex vivo gene therapy with gamma(c) can safely correct the immune deficiency of patients with X-linked severe combined immunodeficiency and allow patients to have a normal life.
Journal ArticleDOI
Use of intravenous immunoglobulin in human disease: A review of evidence by members of the Primary Immunodeficiency Committee of the American Academy of Allergy, Asthma and Immunology
Jordan S. Orange,Elham Hossny,Catherine R. Weiler,Mark Ballow,Melvin Berger,Francisco A. Bonilla,Rebecca H. Buckley,Javier Chinen,Yehia El-Gamal,Bruce Mazer,Robert P. Nelson,Dhavalkumar D. Patel,Elizabeth Secord,Ricardo U. Sorensen,Richard L. Wasserman,Charlotte Cunningham-Rundles +15 more
TL;DR: In this review, the evidence underlying a wide variety of IGIV uses is evaluated and specific recommendations on the basis of these data are made.
Journal ArticleDOI
Efficacy of Gene Therapy for X-Linked Severe Combined Immunodeficiency
Salima Hacein-Bey-Abina,Julia Hauer,Annick Lim,Capucine Picard,Gary P. Wang,Charles C. Berry,Chantal Martinache,Frédéric Rieux-Laucat,Sylvain Latour,Bernd H. Belohradsky,Lily E. Leiva,Ricardo U. Sorensen,Marianne Debré,Jean-Laurent Casanova,Stéphane Blanche,Anne Durandy,Frederic D. Bushman,Alain Fischer,Marina Cavazzana-Calvo +18 more
TL;DR: After nearly 10 years of follow-up, gene therapy was shown to have corrected the immunodeficiency associated with SCID-X1 and may be an option for patients who do not have an HLA-identical donor for hematopoietic stem-cell transplantation and for whom the risks are deemed acceptable.
Iconographies supplémentaires de l'article : Practice parameter for the diagnosis and management of primary immunodeficiency
Francisco A. Bonilla,David A. Khan,Zuhair K. Ballas,Javier Chinen,Michael M. Frank,Joyce T. Hsu,Michael D. Keller,Lisa Kobrynski,Hirsh D. Komarow,Bruce Mazer,Robert P. Nelson,Jordan S. Orange,John M. Routes,William T. Shearer,Ricardo U. Sorensen,James W. Verbsky,David I. Bernstein,Joann Blessing-Moore,David Lang,Richard A. Nicklas,John Oppenheimer,Jay M Portnoy,Christopher Randolph,Diane E. Schuller,Sheldon L. Spector,S. Tilles,Dana V. Wallace,D.A. Khan +27 more
TL;DR: This document incorporated the efforts of many participants, and no single individual, including those who served on the Joint Task Force, is authorized to provide an official AAAAI or ACAAI interpretation of these practice parameters.