R
Richard B. Miles
Researcher at Texas A&M University
Publications - 790
Citations - 27199
Richard B. Miles is an academic researcher from Texas A&M University. The author has contributed to research in topics: Laser & Rayleigh scattering. The author has an hindex of 78, co-authored 759 publications receiving 25239 citations. Previous affiliations of Richard B. Miles include Pierre-and-Marie-Curie University & Langley Research Center.
Papers
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Journal ArticleDOI
Differences between somatic and dendritic inhibition in the hippocampus
Richard B. Miles,Katalin Tóth,Katalin Tóth,Attila I. Gulyás,Attila I. Gulyás,Norbert Hájos,Tamás F. Freund +6 more
TL;DR: Hippocampal synaptic inhibition is mediated by distinct groups of inhibitory cells that may differentially control dendritic electrogenesis and axonal output of hippocampal pyramidal cells.
Journal ArticleDOI
On the origin of interictal activity in human temporal lobe epilepsy in vitro.
TL;DR: A spontaneous, rhythmic activity initiated in the subiculum of slices from patients with temporal lobe epilepsy was described, similar to interictal discharges of patient electroencephalograms.
Book
Neuronal Networks of the Hippocampus
Roger D. Traub,Richard B. Miles +1 more
TL;DR: Using a combined experimental-theoretical approach unique in neuroscience, the authors present important new techniques for the physiological reconstruction of a large biological neuronal network in the CA3 hippocampal region in vitro.
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A model of a CA3 hippocampal pyramidal neuron incorporating voltage-clamp data on intrinsic conductances.
TL;DR: After these alterations, tonic depolarization of the soma leads to adapting repetitive firing, whereas stimulation of the distal dendrites leads to bursting, and a critical set of parameters concerns the regulation of the pool of intracellular [Ca2+] that interacts with membrane channels (gK(C) and gK(AHP)), particularly in the dendrite.
Journal ArticleDOI
Perturbed Chloride Homeostasis and GABAergic Signaling in Human Temporal Lobe Epilepsy
Gilles Huberfeld,Lucia Wittner,Stéphane Clemenceau,Michel Baulac,Kai Kaila,Richard B. Miles,Claudio Rivera +6 more
TL;DR: It is observed that all cells that were hyperpolarized during interictal events were immunopositive for KCC2, whereas the majority of depolarized cells were immunonegative.