Richard B. Miles

TL;DR: The present study addresses the cellular mechanisms of more prolonged epileptic events, lasting 200 ms and more, that may represent short‐duration seizures.

TL;DR: In this paper, the authors performed non-intrusive measurements of the streamwise velocity in turbulent round jets in air by recording short-time displacements and distorsions of very thin tagging lines written spanwise into the flow.

TL;DR: This study shows that epileptic activities are sustained by excitatory effects of GABA in human peritumoral neocortex, as reported in temporal lobe epilepsies, suggesting that both glutamate and GABA signaling and cellular chloride regulation processes, all also involved in oncogenesis, induce an imbalance between synaptic excitation and inhibition underlying epileptic discharges in glioma patients.

TL;DR: These findings provided evidence of frequent (37%) loss-of-function mutations in DEPDC5 associated with a broad spectrum of focal epilepsies and the implication of a DEP domain–containing protein that may be involved in membrane trafficking and/or G protein signaling opens new avenues for research.

TL;DR: Mechanisms underlying the propagation of synchronous epileptiform activity in disinhibited hippocampal slices were examined in experimental and computer simulation studies and the effects of varying synaptic strength and connectivity on the spread of activity in the model was examined.