R
Richard Lathe
Researcher at University of Edinburgh
Publications - 179
Citations - 20987
Richard Lathe is an academic researcher from University of Edinburgh. The author has contributed to research in topics: Gene & Transgene. The author has an hindex of 52, co-authored 172 publications receiving 19962 citations. Previous affiliations of Richard Lathe include Centre national de la recherche scientifique & University of Strasbourg.
Papers
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Journal ArticleDOI
Fatty-acylation target sequence in the ligand-binding domain of vertebrate steroid receptors demarcates evolution from estrogen-related receptors.
Richard Lathe,Douglas R. Houston +1 more
TL;DR: It is reported that target sequences for fatty-acylation (palmitoylation) at a key cysteine residue in helix 8 of the ligand-binding domain accurately demarcate steroid-activated NRs from ERRs.
Journal ArticleDOI
Sex ratios provide evidence for monozygotic twinning in the ring-tailed lemur, Lemur catta.
TL;DR: In this protected species, where twinning is commonplace, the probable existence of frequent MZ twinning has ramifications for breeding programs aimed to maximize genetic diversity, and suggests that twin studies in a species other than human could have potential as a medical research tool.
Patent
Vaccine against rabies and preparation process thereof
TL;DR: Virus of the vaccina characterized in that it comprises all or part of an ADN(I) sequence coding for an antigenic glycoprotein of rabies as discussed by the authors.
Patent
Method for preparing steroids modified by yeast fermentation
TL;DR: In this paper, a method for producing hydroxylated and/or acetylated steroid comprising steps which consist in: culturing yeasts on a medium comprising at least a precursor of such hydroxymated and oracetylated steroids; then isolating the hydroxylated and or acetylate steroids from the medium after bioconversion.
Journal ArticleDOI
Abnormally large, heavy brain with a decreased number of apoptotic cells in CYP7B1 knockout mice
Nobuhiro Sugiyama,Sandra Andersson,Richard Lathe,Xianfeng Fan,Paloma Alonso-Magdalena,Thomas Schwend,Ivan Nalvarte,Margaret Warner,Jan-Åke Gustafsson +8 more
TL;DR: Abnormally large, heavy brain with a decreased number of apoptotic cells in CYP7B1 knockout mice and an increase in the number of mitochondria are observed in knockout mice.