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Richard M. Weinshilboum

Researcher at Mayo Clinic

Publications -  571
Citations -  33641

Richard M. Weinshilboum is an academic researcher from Mayo Clinic. The author has contributed to research in topics: Pharmacogenetics & Thiopurine methyltransferase. The author has an hindex of 86, co-authored 529 publications receiving 31166 citations. Previous affiliations of Richard M. Weinshilboum include University of Rochester & Royal Hallamshire Hospital.

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Journal ArticleDOI

Citalopram and escitalopram plasma drug and metabolite concentrations: genome-wide associations

Yuan Ji, +13 more
- 01 Aug 2014 - 
TL;DR: Genome-wide significant associations were observed for S-CT concentration with SNPs in or near the CYP2C19 gene on chromosome 10, supporting the important role of these cytochrome P450 (CYP) enzymes in biotransformation of citalopram and novel genomic loci that will require future replication and functional validation are identified.
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Human platelet phenol sulphotransferase: Assay procedure, substrate and tissue correlations

Robert J. Anderson, +3 more
- 05 Mar 1981 - 
TL;DR: The possibility that human platelet PST activity measured with 3-methoxy-4-hydroxyphenylglycol as substrate might reflect the enzyme activity in other tissues and the degree of sulfate conjugation of a variety of substrates is raised.
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Electronic Medical Record-Integrated Pharmacogenomics and Related Clinical Decision Support Concepts.

Pedro J. Caraballo, +3 more
- 01 Aug 2017 - 
TL;DR: Current strategies to implement PGx using EHR‐CDS functionalities are reviewed, with a focus on integrating clinical decision support tools in the EHR for translating PGx into clinical practice.
Journal ArticleDOI

Human Brain Phenol Sulfotransferase: Biochemical Properties and Regional Localization

William F. Young, +3 more
- 01 Sep 1984 - 
TL;DR: It is found that the human brain contains at least two forms of PST, forms that are similar to the platelet TS and TL forms of the enzyme with respect to substrate specificity, apparent Km constants, thermal stability, and sensitivity to inhibitors.
Journal Article

Erratum: Olsalazine and 6-mercaptopurine-related bone marrow suppression: A possible drug-drug interaction (Clinical Pharmacology and Therapeutics (1997) 62 (464-475))

L. D. Lewis, +6 more
- 01 Jan 2000 -