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Richard N. Bergman

Researcher at Cedars-Sinai Medical Center

Publications -  489
Citations -  97005

Richard N. Bergman is an academic researcher from Cedars-Sinai Medical Center. The author has contributed to research in topics: Insulin & Insulin resistance. The author has an hindex of 130, co-authored 477 publications receiving 91718 citations. Previous affiliations of Richard N. Bergman include University of Southern California & University of California, Los Angeles.

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Reduced Insulin Sensitivity in Nondiabetic, HLA-Identical Siblings of Insulin-dependent Diabetic Subjects

TL;DR: The insulin sensitivity index was significantly lower in the HLA-identical siblings compared with their matched controls and was determined after an intravenous glucose tolerance test (IVGTT) using the minimal model of insulin kinetics.
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Oscillations enhance the efficiency and stability of glucose disposal.

TL;DR: It is demonstrated that the presence of coordinated oscillations in glucose and insulin, during glucose infusion, are associated with more efficient disposal of glucose than when oscillations are suppressed, suggesting that oscillations may play an important role in theefficient disposal of administered nutrient and may be an important component of normal glucose tolerance.
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Experimental hyperlipidemia dramatically reduces access of insulin to canine skeletal muscle.

TL;DR: The diversion of insulin from the interstitium under hyperlipidemic conditions may play a role in the insulin resistance observed coincident with elevated nocturnal FFAs as is observed in obesity.