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Richard N. Bergman
Researcher at Cedars-Sinai Medical Center
Publications - 489
Citations - 97005
Richard N. Bergman is an academic researcher from Cedars-Sinai Medical Center. The author has contributed to research in topics: Insulin & Insulin resistance. The author has an hindex of 130, co-authored 477 publications receiving 91718 citations. Previous affiliations of Richard N. Bergman include University of Southern California & University of California, Los Angeles.
Papers
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123-LB: Extended Fasting Reveals Effect of Canagliflozin to Mobilize Ketones in Canines
TL;DR: Effect of SGLT2i on ketones is manifest after 24 h of total food restriction, after which reduction in carbohydrate stores switches animals to fat-based metabolism, characterized by increased FFA and ketosis.
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Dapagliflozin prevents abdominal visceral and subcutaneous adipose tissue dysfunction in the insulin‐resistant canine model
Morvarid Kabir,Richard N. Bergman,Darko Stefanovski,Rebecca L. Paszkiewicz,Francesca Piccinini,Orison O. Woolcott,Vs. Gopaul,Linsey Stiles,Cathryn M. Kolka +8 more
TL;DR: In this paper , the effects of the SGLT2i dapagliflozin (DAPA) on subcutaneous (SC) and visceral (VIS) adipose tissue function remain unclear.
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1342-P: Reduction of Glucokinase and Glucokinase Regulatory Protein Expression by siRNA Is Associated with the Reduction of Lactate and Pyruvate Export from Canine Hepatocytes
TL;DR: It is shown that direct suppression of GCK and GKRP genes by siRNA in vitro affects glucose-responsive glycolysis genes, consequently reducing lactate export which can be used as a surrogate for reduced glucokinase activity in hepatocytes.
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365-OR: A Machine-Learning Approach to Estimate Insulin Resistance from Untargeted Metabolomics Data
Nicholette Allred,Fang-Chi Hsu,Shyh-Huei Chen,Maggie C.Y. Ng,Mark O. Goodarzi,Jerome I. Rotter,Lynne E. Wagenknecht,Michael P. Bancks,Richard N. Bergman,Donald W. Bowden +9 more
TL;DR: In this paper , the authors developed estimation models for the dynamic measure of insulin sensitivity (SI) and the basal measure of homeostatic model assessment of IR (HOMAIR) from metabolomics data combined with minimal clinical data, e.g. age, sex, BMI.
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Correction: Paszkiewicz et al. A Peripheral CB1R Antagonist Increases Lipolysis, Oxygen Consumption Rate, and Markers of Beiging in 3T3-L1 Adipocytes Similar to RIM, Suggesting That Central Effects Can Be Avoided. Int. J. Mol. Sci. 2020, 21, 6639.
Rebecca L. Paszkiewicz,Richard N. Bergman,Roberta de Souza Santos,Aaron P. Frank,Orison O. Woolcott,Malini S. Iyer,Darko Stefanovski,Deborah J. Clegg,Morvarid Kabir +8 more