R
Richard N. Bergman
Researcher at Cedars-Sinai Medical Center
Publications - 489
Citations - 97005
Richard N. Bergman is an academic researcher from Cedars-Sinai Medical Center. The author has contributed to research in topics: Insulin & Insulin resistance. The author has an hindex of 130, co-authored 477 publications receiving 91718 citations. Previous affiliations of Richard N. Bergman include University of Southern California & University of California, Los Angeles.
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Journal ArticleDOI
An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans
Robert A. Scott,Laura J. Scott,Reedik Mägi,Letizia Marullo,Kyle J. Gaulton,Kyle J. Gaulton,Marika Kaakinen,Natalia Pervjakova,Tune H. Pers,Andrew D. Johnson,John D. Eicher,Anne U. Jackson,Teresa Ferreira,Yeji Lee,Clement Ma,Valgerdur Steinthorsdottir,Gudmar Thorleifsson,Lu Qi,Lu Qi,Natalie R. van Zuydam,Natalie R. van Zuydam,Anubha Mahajan,Han Chen,Peter Almgren,B F Voight,Harald Grallert,Martina Müller-Nurasyid,Janina S. Ried,Nigel W. Rayner,Nigel W. Rayner,Nigel W. Rayner,Neil Robertson,Neil Robertson,Lennart C. Karssen,Elisabeth M. van Leeuwen,Sara M. Willems,Sara M. Willems,Christian Fuchsberger,Phoenix Kwan,Tanya M. Teslovich,Pritam Chanda,Man Li,Yingchang Lu,Christian Dina,Dorothée Thuillier,Loic Yengo,Longda Jiang,Thomas Sparsø,Hans A. Kestler,Hans A. Kestler,Himanshu Chheda,Lewin Eisele,Stefan Gustafsson,Mattias Frånberg,Mattias Frånberg,Mattias Frånberg,Rona J. Strawbridge,Rafn Benediktsson,Astradur B. Hreidarsson,Augustine Kong,Gunnar Sigurðsson,Nicola D. Kerrison,Jian'an Luan,Liming Liang,Thomas Meitinger,Michael Roden,Barbara Thorand,Tõnu Esko,Tõnu Esko,Tõnu Esko,Evelin Mihailov,Caroline S. Fox,Ching-Ti Liu,Denis Rybin,Bo Isomaa,Valeriya Lyssenko,Tiinamaija Tuomi,David Couper,James S. Pankow,Niels Grarup,Christian Theil Have,Marit E. Jørgensen,Torben Jørgensen,Torben Jørgensen,Allan Linneberg,Allan Linneberg,Marilyn C. Cornelis,Rob M. van Dam,Rob M. van Dam,David J. Hunter,Peter Kraft,Qi Sun,Qi Sun,Sarah Edkins,Katharine R. Owen,Katharine R. Owen,John R. B. Perry,Andrew R. Wood,Eleftheria Zeggini,Juan Tajes-Fernandes,Gonçalo R. Abecasis,Lori L. Bonnycastle,Peter S. Chines,Heather M. Stringham,Heikki A. Koistinen,Heikki A. Koistinen,Heikki A. Koistinen,Leena Kinnunen,Leena Kinnunen,Leena Kinnunen,Bengt Sennblad,Bengt Sennblad,Thomas W. Mühleisen,Markus M. Nöthen,Sonali Pechlivanis,Damiano Baldassarre,Karl Gertow,Steve E. Humphries,Elena Tremoli,Norman Klopp,Julia Meyer,Gerald Steinbach,Roman Wennauer,Johan G. Eriksson,Satu Mӓnnistö,Leena Peltonen,Emmi Tikkanen,Guillaume Charpentier,E. Eury,Stéphane Lobbens,Bruna Gigante,Karin Leander,Olga McLeod,Erwin P. Bottinger,Omri Gottesman,Douglas M. Ruderfer,Matthias Blüher,Peter Kovacs,Anke Tönjes,Nisa M. Maruthur,Chiara Scapoli,Raimund Erbel,Karl-Heinz Jöckel,Susanne Moebus,Ulf de Faire,Anders Hamsten,Michael Stumvoll,Panagiotis Deloukas,Panagiotis Deloukas,Peter Donnelly,Peter Donnelly,Timothy M. Frayling,Andrew T. Hattersley,Samuli Ripatti,Veikko Salomaa,Nancy L. Pedersen,Bernhard O. Boehm,Richard N. Bergman,Francis S. Collins,Karen L. Mohlke,Jaakko Tuomilehto,Torben Hansen,Torben Hansen,Oluf Pedersen,Inês Barroso,Inês Barroso,Lars Lannfelt,Erik Ingelsson,Erik Ingelsson,Lars Lind,Cecilia M. Lindgren,Cecilia M. Lindgren,Stéphane Cauchi,Philippe Froguel,Philippe Froguel,Ruth J. F. Loos,Beverley Balkau,Beverley Balkau,Heiner Boeing,Paul W. Franks,Paul W. Franks,Aurelio Barricarte Gurrea,Domenico Palli,Yvonne T. van der Schouw,David Altshuler,Leif Groop,Leif Groop,Claudia Langenberg,Nicholas J. Wareham,Eric J.G. Sijbrands,Cornelia M. van Duijn,Jose C. Florez,Jose C. Florez,James B. Meigs,James B. Meigs,Eric Boerwinkle,Eric Boerwinkle,Christian Gieger,Konstantin Strauch,Andres Metspalu,Andrew D. Morris,Colin N. A. Palmer,Frank B. Hu,Frank B. Hu,Unnur Thorsteinsdottir,Unnur Thorsteinsdottir,Kari Stefansson,Kari Stefansson,Josée Dupuis,Andrew P. Morris,Michael Boehnke,Mark I. McCarthy,Mark I. McCarthy,Mark I. McCarthy,Inga Prokopenko,Inga Prokopenko,Inga Prokopenko +216 more
TL;DR: This article conducted a meta-analysis of genome-wide association data from 26,676 T2D case and 132,532 control subjects of European ancestry after imputation using the 1000 Genomes multiethnic reference panel.
Journal ArticleDOI
Free Fatty Acids and Pathogenesis of Type 2 Diabetes Mellitus
Richard N. Bergman,Marilyn Ader +1 more
TL;DR: Overall, effects of FFA can lead to several components of the insulin resistance syndrome and risk for diabetes.
Journal ArticleDOI
Estimation of endogenous glucose production during hyperinsulinemic-euglycemic glucose clamps: comparison of unlabeled and labeled exogenous glucose infusates
TL;DR: The one-compartment, fixed pool volume model of glucose kinetics is inadequate for the estimation of Ra during euglycemic glucose clamps and two new strategies for estimating Ra from the one-Compartment model, the hot GINF protocol and the regression method calculation, yielded more accurate and physiologically plausible estimates of Ra than currently used methodology.
Journal ArticleDOI
The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study
Thomas W. Winkler,Anne E. Justice,Mariaelisa Graff,Llilda Barata,Mary F. Feitosa,Su H. Chu,Jacek Czajkowski,Tõnu Esko,Tove Fall,Tuomas O. Kilpeläinen,Yingchang Lu,Reedik Mägi,Evelin Mihailov,Tune H. Pers,Sina Rüeger,Alexander Teumer,Georg Ehret,Teresa Ferreira,Nancy L. Heard-Costa,Juha Karjalainen,Vasiliki Lagou,Anubha Mahajan,Michael D. Neinast,Inga Prokopenko,Jeannette Simino,Tanya M. Teslovich,Rick Jansen,Harm-Jan Westra,Charles C. White,Devin Absher,Tarunveer S. Ahluwalia,Shafqat Ahmad,Eva Albrecht,Alexessander Couto Alves,Jennifer L. Bragg-Gresham,Anton J. M. de Craen,Joshua C. Bis,Amélie Bonnefond,Gabrielle Boucher,Gemma Cadby,Yu-Ching Cheng,Charleston W. K. Chiang,Graciela Delgado,Ayse Demirkan,Nicole Dueker,Niina Eklund,Gudny Eiriksdottir,Joel Eriksson,Bjarke Feenstra,Krista Fischer,Francesca Frau,Tessel E. Galesloot,Frank Geller,Anuj Goel,Mathias Gorski,Tanja B. Grammer,Stefan Gustafsson,Saskia Haitjema,Jouke-Jan Hottenga,Jennifer E. Huffman,Anne U. Jackson,Kevin B. Jacobs,Åsa Johansson,Marika Kaakinen,Marcus E. Kleber,Jari Lahti,Irene Mateo Leach,Benjamin Lehne,Youfang Liu,Ken Sin Lo,Mattias Lorentzon,Jian'an Luan,Pamela A. F. Madden,Massimo Mangino,Barbara McKnight,Carolina Medina-Gomez,Keri L. Monda,May E. Montasser,Gabriele Müller,Martina Müller-Nurasyid,Ilja M. Nolte,Kalliope Panoutsopoulou,Laura Pascoe,Lavinia Paternoster,Nigel W. Rayner,Frida Renström,Federica Rizzi,Lynda M. Rose,Kathy Ryan,Perttu Salo,Serena Sanna,Hubert Scharnagl,Jianxin Shi,Albert V. Smith,Lorraine Southam,Alena Stančáková,Valgerdur Steinthorsdottir,Rona J. Strawbridge,Yun Ju Sung,Ioanna Tachmazidou,Toshiko Tanaka,Gudmar Thorleifsson,Stella Trompet,Natalia Pervjakova,Jonathan Tyrer,Liesbeth Vandenput,Sander W. van der Laan,Nathalie van der Velde,Jessica van Setten,Jana V. van Vliet-Ostaptchouk,Niek Verweij,Efthymia Vlachopoulou,Lindsay L. Waite,Sophie R. Wang,Zhaoming Wang,Sarah H. Wild,Christina Willenborg,James F. Wilson,Andrew Wong,Jian Yang,Loic Yengo,Laura M. Yerges-Armstrong,Lei Yu,Weihua Zhang,Jing Hua Zhao,Ehm A. Andersson,Stephan J. L. Bakker,Damiano Baldassarre,Karina Banasik,Matteo Barcella,Cristina Barlassina,Claire Bellis,Paola Benaglio,John Blangero,Matthias Blüher,Fabrice Bonnet,Lori L. Bonnycastle,Heather A. Boyd,Marcel Bruinenberg,Aron S. Buchman,Harry Campbell,Yii-Der Ida Chen,Peter S. Chines,Simone Claudi-Boehm,John B. Cole,Francis S. Collins,Eco J. C. de Geus,Lisette C. P. G. M. de Groot,Maria Dimitriou,Jubao Duan,Stefan Enroth,Elodie Eury,Aliki-Eleni Farmaki,Nita G. Forouhi,Nele Friedrich,Pablo V. Gejman,Bruna Gigante,Nicola Glorioso,Alan S. Go,Omri Gottesman,Jürgen Gräßler,Harald Grallert,Niels Grarup,Yu Mei Gu,Linda Broer,Annelies C. Ham,Torben Hansen,Tamara B. Harris,Catharina A. Hartman,Maija Hassinen,Nicholas D. Hastie,Andrew T. Hattersley,Andrew C. Heath,Anjali K. Henders,Dena G. Hernandez,Hans L. Hillege,Oddgeir L. Holmen,Kees Hovingh,Jennie Hui,Lise Lotte N. Husemoen,Nina Hutri-Kähönen,Pirro G. Hysi,Thomas Illig,Philip L. De Jager,Shapour Jalilzadeh,Torben Jørgensen,J. Wouter Jukema,Markus Juonala,Stavroula Kanoni,Maria Karaleftheri,Kay-Tee Khaw,Leena Kinnunen,Steven J. Kittner,Wolfgang Koenig,Ivana Kolcic,Peter Kovacs,Nikolaj T. Krarup,Wolfgang Kratzer,Janine Krüger,Diana Kuh,Meena Kumari,Theodosios Kyriakou,Claudia Langenberg,Lars Lannfelt,Chiara Lanzani,Vaneet Lotay,Lenore J. Launer,Karin Leander,Jaana Lindström,Allan Linneberg,Yan Ping Liu,Stéphane Lobbens,Robert Luben,Valeriya Lyssenko,Satu Männistö,Patrik K. E. Magnusson,Wendy L. McArdle,Cristina Menni,Sigrun Merger,Lili Milani,Grant W. Montgomery,Andrew P. Morris,Narisu Narisu,Mari Nelis,Ken K. Ong,Aarno Palotie,Louis Pérusse,Irene Pichler,Maria Grazia Pilia,Anneli Pouta,Myriam Rheinberger,Rasmus Ribel-Madsen,Marcus Richards,Kenneth Rice,Treva Rice,Carlo Rivolta,Veikko Salomaa,Alan R. Sanders,Mark A. Sarzynski,Salome Scholtens,Robert A. Scott,William R. Scott,Sylvain Sebert,Sebanti Sengupta,Bengt Sennblad,Thomas Seufferlein,Angela Silveira,P. Eline Slagboom,Jan Smit,Thomas Sparsø,Kathleen Stirrups,Ronald P. Stolk,Heather M. Stringham,Morris A. Swertz,Amy J. Swift,Ann-Christine Syvänen,Sian Tsung Tan,Barbara Thorand,Anke Tönjes,Angelo Tremblay,Emmanouil Tsafantakis,Peter J. van der Most,Uwe Völker,Marie-Claude Vohl,Judith M. Vonk,Melanie Waldenberger,Ryan W. Walker,Roman Wennauer,Elisabeth Widen,Gonneke Willemsen,Tom Wilsgaard,Alan F. Wright,M. Carola Zillikens,Suzanne C. van Dijk,Natasja M. van Schoor,Folkert W. Asselbergs,Paul I.W. de Bakker,Jacques S. Beckmann,John Beilby,David A. Bennett,Richard N. Bergman,Sven Bergmann,Carsten A. Böger,Bernhard O. Boehm,Eric Boerwinkle,Dorret I. Boomsma,Stefan R. Bornstein,Erwin P. Bottinger,Claude Bouchard,John C. Chambers,Stephen J. Chanock,Daniel I. Chasman,Francesco Cucca,Daniele Cusi,George Dedoussis,Jeanette Erdmann,Johan G. Eriksson,Denis A. Evans,Ulf de Faire,Martin Farrall,Luigi Ferrucci,Ian Ford,Lude Franke,Paul W. Franks,Philippe Froguel,Ron T. Gansevoort,Christian Gieger,Henrik Grönberg,Vilmundur Gudnason,Ulf Gyllensten,Per Hall,Anders Hamsten,Pim van der Harst,Caroline Hayward,Markku Heliövaara,Christian Hengstenberg,Andrew A. Hicks,Aroon D. Hingorani,Albert Hofman,Frank B. Hu,Heikki V. Huikuri,Kristian Hveem,Alan L. James,Joanne M. Jordan,Antti Jula,Mika Kähönen,Eero Kajantie,Sekar Kathiresan,Lambertus A. Kiemeney,Mika Kivimäki,Paul Knekt,Heikki A. Koistinen,Jaspal S. Kooner,Seppo Koskinen,Johanna Kuusisto,Winfried Maerz,Nicholas G. Martin,Markku Laakso,Timo A. Lakka,Terho Lehtimäki,Guillaume Lettre,Douglas F. Levinson,Lars Lind,Marja-Liisa Lokki,Pekka Mäntyselkä,Mads Melbye,Andres Metspalu,Braxton D. Mitchell,Frans L. Moll,Jeffrey C. Murray,Arthur W. Musk,Markku S. Nieminen,Inger Njølstad,Claes Ohlsson,Albertine J. Oldehinkel,Ben A. Oostra,Lyle J. Palmer,James S. Pankow,Gerard Pasterkamp,Nancy L. Pedersen,Oluf Pedersen,Brenda W.J.H. Penninx,Markus Perola,Annette Peters,Ozren Polasek,Peter P. Pramstaller,Bruce M. Psaty,Lu Qi,Thomas Quertermous,Olli T. Raitakari,Tuomo Rankinen,Rainer Rauramaa,Paul M. Ridker,John D. Rioux,Fernando Rivadeneira,Jerome I. Rotter,Igor Rudan,Hester M. den Ruijter,Juha Saltevo,Naveed Sattar,Heribert Schunkert,Peter Schwarz,Alan R. Shuldiner,Juha Sinisalo,Harold Snieder,Thorkild I. A. Sørensen,Tim D. Spector,Jan A. Staessen,Bandinelli Stefania,Unnur Thorsteinsdottir,Michael Stumvoll,Jean-Claude Tardif,Elena Tremoli,Jaakko Tuomilehto,André G. Uitterlinden,Matti Uusitupa,André L. M. Verbeek,Sita H. Vermeulen,Jorma Viikari,Veronique Vitart,Henry Völzke,Peter Vollenweider,Gérard Waeber,Mark Walker,Henri Wallaschofski,Nicholas J. Wareham,Hugh Watkins,Eleftheria Zeggini,Aravinda Chakravarti,Deborah J. Clegg,L. Adrienne Cupples,Penny Gordon-Larsen,Cashell E. Jaquish,Dabeeru C. Rao,Gonçalo R. Abecasis,Themistocles L. Assimes,Inês Barroso,Sonja I. Berndt,Michael Boehnke,Panos Deloukas,Caroline S. Fox,Leif Groop,David J. Hunter,Erik Ingelsson,Robert C. Kaplan,Mark I. McCarthy,Karen L. Mohlke,Jeffrey R. O'Connell,David Schlessinger,David P. Strachan,Kari Stefansson,Cornelia M. van Duijn,Joel N. Hirschhorn,Cecilia M. Lindgren,Iris M. Heid,Kari E. North,Ingrid B. Borecki,Zoltán Kutalik,Ruth J. F. Loos +438 more
TL;DR: In this paper, the authors performed meta-analyses of 114 studies with genome-wide chip and/or Metabochip data by the Genetic Investigation of Anthropometric Traits (GIANT) Consortium.
Journal ArticleDOI
The insulin resistance atherosclerosis study (IRAS) objectives, design, and recruitment results.
Lynne E. Wagenknecht,Elizabeth J. Mayer,Marian Rewers,Steven M. Haffner,Joseph V. Selby,Gerald M. Borok,Leora Henkin,George Howard,Peter J. Savage,Mohammed F. Saad,Richard N. Bergman,Richard F. Hamman +11 more
TL;DR: Forthcoming cross-sectional analyses will help to disentangle the association between insulin resistance and CVD, apart from the concomitant hyperinsulinemia and related CVD risk factors.