R
Richard N. Bergman
Researcher at Cedars-Sinai Medical Center
Publications - 489
Citations - 97005
Richard N. Bergman is an academic researcher from Cedars-Sinai Medical Center. The author has contributed to research in topics: Insulin & Insulin resistance. The author has an hindex of 130, co-authored 477 publications receiving 91718 citations. Previous affiliations of Richard N. Bergman include University of Southern California & University of California, Los Angeles.
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Journal ArticleDOI
Liver glucose production in health and diabetes
Journal ArticleDOI
Activation of NPRs and UCP1-independent pathway following CB1R antagonist treatment is associated with adipose tissue beiging in fat-fed male dogs.
Malini S. Iyer,Rebecca L. Paszkiewicz,Richard N. Bergman,Joyce M. Richey,Orison O. Woolcott,Isaac Asare-Bediako,Qiang Wu,Stella P. Kim,Darko Stefanovski,Cathryn M. Kolka,Deborah J. Clegg,Morvarid Kabir +11 more
TL;DR: The data suggest that the upregulation of NPRs, β-1R and β-3R, lipolysis, and SERCA2b and RYR2 may be one of the mechanisms by which RIM promotes beiging and overall the improvement of metabolic homeostasis induced by RIM.
Genome-wide physical activity interactions in adiposity. A meta-analysis of 200,452 adults
Mariaelisa Graff,Robert A. Scott,Anne E. Justice,Kristin L. Young,Mary F. Feitosa,Llilda Barata,Thomas W. Winkler,Audrey Y. Chu,Anubha Mahajan,David Hadley,Luting Xue,Tsegaselassie Workalemahu,Nancy L. Heard-Costa,Marcel den Hoed,Tarunveer S. Ahluwalia,Qibin Qi,Julius S. Ngwa,Frida Renström,Lydia Quaye,John D. Eicher,James E. Hayes,Marilyn C. Cornelis,Zoltán Kutalik,Elise Lim,Jian'an Luan,Jennifer E. Huffman,Weihua Zhang,Wei Zhao,Paula J. Griffin,Toomas Haller,Shafqat Ahmad,Pedro Marques-Vidal,Stephanie A. Bien,Loic Yengo,Alexander Teumer,Albert V. Smith,Meena Kumari,Marie Neergaard Harder,Johanne Marie Justesen,Marcus E. Kleber,Mette Hollensted,Kurt Lohman,Natalia V. Rivera,John Whitfield,Jing Hua Zhao,Heather M. Stringham,Leo-Pekka Lyytikäinen,Charlotte Huppertz,Gonneke Willemsen,Wouter J. Peyrot,Ying Wu,Kati Kristiansson,Ayse Demirkan,Myriam Fornage,Maija Hassinen,Lawrence F. Bielak,Gemma Cadby,Toshiko Tanaka,Reedlk Magl,Peter J. van der Most,Anne U. Jackson,Jennifer L. Bragg-Gresham,Veronique Vitart,Jonathan Marten,Pau Navarro,Claire Bellis,Dorota Pasko,Åsa Johansson,Soren Snitker,Yu-Ching Cheng,Joel Eriksson,Unhee Lim,Mette Aadahl,Linda S. Adair,Najaf Amin,Beverley Balkau,Juha Auvinen,John Beilby,Richard N. Bergman,Sven Bergmann,Alain G. Bertoni,John Blangero,Amelle Bonnefond,Lori L. Bonnycastle,Judith B. Borja,Soren Brage,Fabio Busonero,Steve Buyske,Harry Campbell,Peter S. Chines,Francis S. Collins,Tanguy Corre,George Davey Smith,Graciela E. Delgado,Nicole Dueker,Marcus Doerr,Tapani Ebeling,Gudny Eiriksdottir,Tõnu Esko,Jessica D. Faul,Mao Fu,Kristine Færch,Christian Gieger,Sven Glaeser,Jian Gong,Penny Gordon-Larsen,Harald Grallert,Tanja B. Grammer,Niels Grarup,Gerard van Grootheest,Kennet Harald,Nicholas D. Hastie,Aki S. Havulinna,Dena G. Hernandez,Lucia A. Hindorff,Lynne J. Hocking,Oddgeir L. Holmens,Christina Holzapfel,Jouke-Jan Hottenga,Jie Huang,Tao Huang,Jennie Hui,Cornelia Huth,Nina Hutri-Kähönen,Alan James,John-Olov Jansson,Min A. Jhun,Markus Juonala,Leena Kinnunen,Heikki A. Koistinen,Ivana Kolcic,Pirjo Komulainen,Johanna Kuusisto,Kirsti Kvaløy,Mika Kähönen,Timo A. Lakka,Lenore J. Launer,Benjamin Lehne,Cecilia M. Lindgren,Mattias Lorentzon,Robert Luben,Michel Marre,Yuri Milaneschi,Keri L. Monda,Grant W. Montgomery,Marleen H.M. de Moor,Antonella Mulas,Martina Mueller-Nurasyid,Arthur W. Musk,Reija Männikkö,Satu Männistö,Narisu Narisu,Matthias Nauck,Jennifer A. Nettleton,Ilja M. Nolte,Albertine J. Oldehinkel,Matthias Olden,Ken K. Ong,Sandosh Padmanabhan,Lavinia Paternoster,Jeremiah Perez,Markus Perola,Annette Peters,Ulrike Peters,Patricia A. Peyser,Inga Prokopenko,Hannu Puolijoki,Olli T. Raitakari,Tuomo Rankinen,Laura J. Rasmussen-Torvik,Rajesh Rawal,Paul M. Ridker,Lynda M. Rose,Igor Rudan,Cinzia Sarti,Mark A. Sarzynski,Kai Savonen,William R. Scott,Serena Sanna,Alan R. Shuldiner,Steve Sidney,Guenther Silbernagel,Blair H. Smith,Jennifer A. Smith,Harold Snieder,Alena Stančáková,Barbara Sternfeld,Amy J. Swift,Tuija Tammelin,Sian-Tsung Tan,Barbara Thorand,Dorothée Thuillier,Liesbeth Vandenput,Henrik Vestergaard,Jana V. van Vliet-Ostaptchouk,Marie-Claude Vohl,Uwe Voelker,Gérard Waeber,Mark Walker,Sarah H. Wild,Andrew Wong,Alan F. Wright,M. Carola Zillikens,Niha Zubair,Christopher A. Haiman,Loic LeMarchand,Ulf Gyllensten,Claes Ohlsson,Albert Hofman,Fernando Rivadeneira,André G. Uitterlinden,Louis Pérusse,James F. Wilson,Caroline Hayward,Ozren Polasek,Francesco Cucca,Kristian Hveem,Catharina A. Hartman,Anke Toenjes,Stefania Bandinelli,Lyle J. Palmer,Sharon L.R. Kardia,Rainer Rauramaa,Thorkild I. A. Sørensen,Jaakko Tuomilehto,Veikko Salomaa,Brenda W.J.H. Penninx,Eco J. C. de Geus,Dorret I. Boomsma,Terho Lehtimäki,Massimo Mangino,Markku Laakso,Claude Bouchard,Nicholas G. Martin,Diana Kuh,Yongmei Liu,Allan Linneberg,Winfried Maerz,Konstantin Strauch,Mika Kivimäki,Tamara B. Harris,Vilmundur Gudnason,Henry Voelzke,Lu Qi,Marjo-Riitta Järvelin,John C. Chambers,Jaspal S. Kooner,Philippe Froguel,Charles Kooperberg,Peter Vollenweider,Göran Hallmans,Torben Hansen,Oluf Pedersen,Andres Metspalu,Nicholas J. Wareham,Claudia Langenberg,David R. Weir,David J. Porteous,Eric Boerwinkle,Daniel I. Chasman,Gonçalo R. Abecasis,Inês Barroso,Mark I. McCarthy,Timothy M. Frayling,Jeffrey R. O'Connell,Cornelia M. van Duijn,Michael Boehnke,Iris M. Heid,Karen L. Mohlke,David P. Strachan,Caroline S. Fox,Ching-Ti Liu,Joel N. Hirschhorn,Robert J. Klein,Andrew D. Johnson,Ingrid B. Borecki,Paul W. Franks,Kari E. North,L. Adrienne Cupples,Ruth J. F. Loos,Tuomas O. Kilpeläinen +280 more
TL;DR: This paper performed genome-wide interaction meta-analyses of BMI and BMI-adjusted waist circumference and waist-hip ratio from up to 200,452 adults of European (n = 180,423) or other ancestry.
Journal ArticleDOI
A Peripheral CB1R Antagonist Increases Lipolysis, Oxygen Consumption Rate, and Markers of Beiging in 3T3-L1 Adipocytes Similar to RIM, Suggesting that Central Effects Can Be Avoided.
Rebecca L. Paszkiewicz,Richard N. Bergman,Roberta de Souza Santos,Aaron P. Frank,Orison O. Woolcott,Malini S. Iyer,Darko Stefanovski,Deborah J. Clegg,Morvarid Kabir +8 more
TL;DR: It is shown, for the first time, that AM6545 significantly increases markers of adipose tissue beiging, mitochondrial biogenesis, and lipolysis in 3T3-L1 adipocytes, supporting the importance of focus on peripheral CB1R antagonism pharmacology for reducing the incidence of obesity and T2D.
Journal ArticleDOI
Lack of hepatic "interregulation" during inhibition of glycogenolysis in a canine model.
TL;DR: In conclusion, infusion of DAB inhibited glycogenolysis; however, the absolute contribution of gluconeogenesis to glucose production was not affected, suggesting that inhibition of glycogensolysis could be an effective antidiabetic treatment.